Bİyopotansiyel işaretlerin ikinci nesil akım taşıyıcılar ile işlenmesi ve yeni bir EKG devresi tasarımı

06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması, Düzenlenmesi ve Erişime Açılmasına İlişkin Yönerge” gereğince tam metin erişime açılmıştır.Anahtar kelimeler: CCII, ikinci nesil akım taşıyıcılar, filtre, EKG Bu çalışmada bir EKG cihazı tasarlanmış ve bu cihaz ikinci nesil akım taşıyıcılar ile gerçekleştirilmiştir. Bu EKG devresinde ikinci nesil akım taşıyıcılar filtre olarak kullanılmıştır. Bu cihazın doğruluğunu kontrol edebilmek ve karşılaştırmasını yapabilmek için Sakarya Üniversitesi Elektrik-Elektronik Mühendisliği'ne ait olan BIOPAC Systems Inc. şirketinin imal ettiği MP36 EKG cihazı ile ölçümler eş zamanlı olarak yapılmıştır. Ayrıca OPAMP'larla tasarlanan bir EKG devresi de gerçekleştirilmiş ve sonuçları değerlendirilmiştir. OPAMP'larla gerçekleştirilen bu devre ikinci nesil akım taşıyıcılarla yeniden dizayn edilmiş ve gerçekleştirilerek sonuçları değerlendirilmiştir. Böylece OPAMP'larla gerçekleştirilmiş bir EKG devresi, ikinci nesil akım taşıyıcılarla yeniden dizayn edilmiş bir EKG devresi, bu çalışmada tasarlanmış ve ikinci nesil akım taşıyıcılarla tasarlanmış bir EKG devresi, MP36 devresi ve daha önce literatürde gerçekleştirilmiş EKG devrelerinin kıyaslaması yapılmıştır. Ayrıca biyomedikal cihazlarda sıklıkla kullanılan filtreler, yükselteçler ve bazı devreler simule edilmiştir. CCII tabanlı olan devrede gürültüler minimuma inmiş ve çok net EKG ölçümü yapılabilmiştir. EKG devresi 9,5*9,5 cm2 boyutlarına kadar indirgenebilmiştir. Entegrelerin ve diğer elemanların SMD türlerinin kullanılması ile daha da küçültülebilmesi mümkündür. Gerçeklenen devre maliyet açısından da avantajlıdır. 4 adet kalem pille çalışabilir olması da bir diğer avantajıdır. CMRR oranı, frekans aralığı, yükseltme oranı ve uygulanabilme kolaylığı açısından CCII tabanlı olan EKG devrelerinin daha avantajlı olduğu sonucu ortaya çıkmaktadır. Ayrıca bu çalışmada rezonans frekansını ayarlamak ve daha iyi sonuç elde edebilmek için CCII yapısına ayarlı dirençler eklenmesi sebebiyle 5 Hz ile 100 MHz arasında bir kesim frekansına sahip bir filtre yapısı öne sürüldü ve bu devrede kullanılabilir olduğu gözlemlendi.Keywords: CCII, second generation current conveyors, filter, ECG In this study, an ECG device was designed and this device was carried out with second generation current carriers. Second generation current carriers were used as filters in this ECG circuit. Measurements were simultaneously performed with MP36 ECG device produced by BIOPAC Systems Inc. that is belong to Sakarya University Electrical and Electronics Engineering Department in order to be able to check and compare accuracy of this device. An ECG circuit designed with OPAMPs was also carried out and results were evaluated. This circuit, which was realized with OPAMPs, was redesigned with second generation current carriers and results were evaluated by performing. Thus, an ECG circuit realized with OPAMPs, a redesigned ECG circuit with second generation current carriers were designed in this study, and an ECG circuit with second generation current carriers, MP36 circuit and previous circuits in literature were compared. In addition, filters, amplifiers and some circuits, which are frequently used in biomedical devices are simulated. Noises were reduced to minimum in CCII-based circuit and very clear ECG measurements was done. ECG circuit can be reduced to size of 9.5 * 9.5 cm2. It is possible to further reduce integrals and other elements by use of SMD types. Performed circuit is also advantageous in terms of cost. Another advantage is that it can work with 4 batteries. It was concluded that CCII based ECG circuits are more advantageous in terms of CMRR ratio, frequency range, amplification rate and ease of application. Also, in this study, a filter structure having a cut-off frequency between 5 Hz to 100 MHz was proposed because of adding adjusted resistors to CCII structure to adjust resonance frequency and achieve better results, and it was observed to be usable in this circuit

Low Voltage Low Power Analogue Circuits Design

Disertační práce je zaměřena na výzkum nejběžnějších metod, které se využívají při návrhu analogových obvodů s využití nízkonapěťových (LV) a nízkopříkonových (LP) struktur. Tyto LV LP obvody mohou být vytvořeny díky vyspělým technologiím nebo také využitím pokročilých technik návrhu. Disertační práce se zabývá právě pokročilými technikami návrhu, především pak nekonvenčními. Mezi tyto techniky patří využití prvků s řízeným substrátem (bulk-driven - BD), s plovoucím hradlem (floating-gate - FG), s kvazi plovoucím hradlem (quasi-floating-gate - QFG), s řízeným substrátem s plovoucím hradlem (bulk-driven floating-gate - BD-FG) a s řízeným substrátem s kvazi plovoucím hradlem (quasi-floating-gate - BD-QFG). Práce je také orientována na možné způsoby implementace známých a moderních aktivních prvků pracujících v napěťovém, proudovém nebo mix-módu. Mezi tyto prvky lze začlenit zesilovače typu OTA (operational transconductance amplifier), CCII (second generation current conveyor), FB-CCII (fully-differential second generation current conveyor), FB-DDA (fully-balanced differential difference amplifier), VDTA (voltage differencing transconductance amplifier), CC-CDBA (current-controlled current differencing buffered amplifier) a CFOA (current feedback operational amplifier). Za účelem potvrzení funkčnosti a chování výše zmíněných struktur a prvků byly vytvořeny příklady aplikací, které simulují usměrňovací a induktanční vlastnosti diody, dále pak filtry dolní propusti, pásmové propusti a také univerzální filtry. Všechny aktivní prvky a příklady aplikací byly ověřeny pomocí PSpice simulací s využitím parametrů technologie 0,18 m TSMC CMOS. Pro ilustraci přesného a účinného chování struktur je v disertační práci zahrnuto velké množství simulačních výsledků.The dissertation thesis is aiming at examining the most common methods adopted by analog circuits' designers in order to achieve low voltage (LV) low power (LP) configurations. The capability of LV LP operation could be achieved either by developed technologies or by design techniques. The thesis is concentrating upon design techniques, especially the non–conventional ones which are bulk–driven (BD), floating–gate (FG), quasi–floating–gate (QFG), bulk–driven floating–gate (BD–FG) and bulk–driven quasi–floating–gate (BD–QFG) techniques. The thesis also looks at ways of implementing structures of well–known and modern active elements operating in voltage–, current–, and mixed–mode such as operational transconductance amplifier (OTA), second generation current conveyor (CCII), fully–differential second generation current conveyor (FB–CCII), fully–balanced differential difference amplifier (FB–DDA), voltage differencing transconductance amplifier (VDTA), current–controlled current differencing buffered amplifier (CC–CDBA) and current feedback operational amplifier (CFOA). In order to confirm the functionality and behavior of these configurations and elements, they have been utilized in application examples such as diode–less rectifier and inductance simulations, as well as low–pass, band–pass and universal filters. All active elements and application examples have been verified by PSpice simulator using the 0.18 m TSMC CMOS parameters. Sufficient numbers of simulated plots are included in this thesis to illustrate the precise and strong behavior of structures.

Utilizing Unconventional CMOS Techniques for Low Voltage Low Power Analog Circuits Design for Biomedical Applications

Tato disertační práce se zabývá navržením nízkonapěťových, nízkopříkonových analogových obvodů, které používají nekonvenční techniky CMOS. Lékařská zařízení na bateriové napájení, jako systémy pro dlouhodobý fyziologický monitoring, přenosné systémy, implantovatelné systémy a systémy vhodné na nošení, musí být male a lehké. Kromě toho je nutné, aby byly tyto systémy vybaveny baterií s dlouhou životností. Z tohoto důvodu převládají v biomedicínských aplikacích tohoto typu nízkopříkonové integrované obvody. Nekonvenční techniky jako např. využití transistorů s řízeným substrátem (Bulk-Driven “BD”), s plovoucím hradlem (Floating-Gate “FG”), s kvazi plovoucím hradlem (Quasi-Floating-Gate “QFG”), s řízeným substrátem s plovoucím hradlem (Bulk-Driven Floating-Gate “BD-FG”) a s řízeným substrátem s kvazi plovoucím hradlem (Bulk-Driven Quasi-Floating-Gate “BD-QFG”), se v nedávné době ukázaly jako efektivní prostředek ke zjednodušení obvodového zapojení a ke snížení velikosti napájecího napětí směrem k prahovému napětí u tranzistorů MOS (MOST). V práci jsou podrobně představeny nejdůležitější charakteristiky nekonvenčních technik CMOS. Tyto techniky byly použity pro vytvoření nízko napěťových a nízko výkonových CMOS struktur u některých aktivních prvků, např. Operational Transconductance Amplifier (OTA) založené na BD, FG, QFG, a BD-QFG techniky; Tunable Transconductor založený na BD MOST; Current Conveyor Transconductance Amplifier (CCTA) založený na BD-QFG MOST; Z Copy-Current Controlled-Current Differencing Buffered Amplifier (ZC-CC-CDBA) založený na BD MOST; Winner Take All (WTA) and Loser Take All (LTA) založený na BD MOST; Fully Balanced Four-Terminal Floating Nullor (FBFTFN) založený na BD-QFG technice. Za účelem ověření funkčnosti výše zmíněných struktur, byly tyto struktury použity v několika aplikacích. Výkon navržených aktivních prvků a příkladech aplikací je ověřován prostřednictvím simulačních programů PSpice či Cadence za použití technologie 0.18 m CMOS.This doctoral thesis deals with designing ultra-low-voltage (LV) low-power (LP) analog circuits utilizing the unconventional CMOS techniques. Battery powered medical devices such as; long term physiological monitoring, portable, implantable, and wearable systems need to be small and lightweight. Besides, long life battery is essential need for these devices. Thus, low-power integrated circuits are always paramount in such biomedical applications. Recently, unconventional CMOS techniques i.e. Bulk-Driven (BD), Floating-Gate (FG), Quasi-Floating-Gate (QFG), Bulk-Driven Floating-Gate (BD-FG) and Bulk-Driven Quasi-Floating-Gate (BD-QFG) MOS transistors (MOSTs) have revealed as effective devices to reduce the circuit complexity and push the voltage supply of the circuit towards threshold voltage of the MOST. In this work, the most important features of the unconventional CMOS techniques are discussed in details. These techniques have been utilized to perform ultra-LV LP CMOS structures of several active elements i.e. Operational Transconductance Amplifier (OTA) based on BD, FG, QFG, and BD-QFG techniques; Tunable Transconductor based on BD MOST; Current Conveyor Transconductance Amplifier (CCTA) based on BD-QFG MOST; Z Copy-Current Controlled-Current Differencing Buffered Amplifier (ZC-CC-CDBA) based on BD MOST; Winner Take All (WTA) and Loser Take All (LTA) based on BD MOST; Fully Balanced Four-Terminal Floating Nullor (FBFTFN) based on BD-QFG technique. Moreover, to verify the workability of the proposed structures, they were employed in several applications. The performance of the proposed active elements and their applications were investigated through PSpice or Cadence simulation program using 0.18 m CMOS technology.

Low-power Wearable Healthcare Sensors

Advances in technology have produced a range of on-body sensors and smartwatches that can be used to monitor a wearer’s health with the objective to keep the user healthy. However, the real potential of such devices not only lies in monitoring but also in interactive communication with expert-system-based cloud services to offer personalized and real-time healthcare advice that will enable the user to manage their health and, over time, to reduce expensive hospital admissions. To meet this goal, the research challenges for the next generation of wearable healthcare devices include the need to offer a wide range of sensing, computing, communication, and human–computer interaction methods, all within a tiny device with limited resources and electrical power. This Special Issue presents a collection of six papers on a wide range of research developments that highlight the specific challenges in creating the next generation of low-power wearable healthcare sensors

CMOS Design of Reconfigurable SoC Systems for Impedance Sensor Devices

La rápida evolución en el campo de los sensores inteligentes, junto con los avances en las tecnologías de la computación y la comunicación, está revolucionando la forma en que recopilamos y analizamos datos del mundo físico para tomar decisiones, facilitando nuevas soluciones que desempeñan tareas que antes eran inconcebibles de lograr.La inclusión en un mismo dado de silicio de todos los elementos necesarios para un proceso de monitorización y actuación ha sido posible gracias a los avances en micro (y nano) electrónica. Al mismo tiempo, la evolución de las tecnologías de procesamiento y micromecanizado de superficies de silicio y otros materiales complementarios ha dado lugar al desarrollo de sensores integrados compatibles con CMOS, lo que permite la implementación de matrices de sensores de alta densidad. Así, la combinación de un sistema de adquisición basado en sensores on-Chip, junto con un microprocesador como núcleo digital donde se puede ejecutar la digitalización de señales, el procesamiento y la comunicación de datos proporciona características adicionales como reducción del coste, compacidad, portabilidad, alimentación por batería, facilidad de uso e intercambio inteligente de datos, aumentando su potencial número de aplicaciones.Esta tesis pretende profundizar en el diseño de un sistema portátil de medición de espectroscopía de impedancia de baja potencia operado por batería, basado en tecnologías microelectrónicas CMOS, que pueda integrarse con el sensor, proporcionando una implementación paralelizable sin incrementar significativamente el tamaño o el consumo, pero manteniendo las principales características de fiabilidad y sensibilidad de un instrumento de laboratorio. Esto requiere el diseño tanto de la etapa de gestión de la energía como de las diferentes celdas que conforman la interfaz, que habrán de satisfacer los requisitos de un alto rendimiento a la par que las exigentes restricciones de tamaño mínimo y bajo consumo requeridas en la monitorización portátil, características que son aún más críticas al considerar la tendencia actual hacia matrices de sensores.A nivel de celdas, se proponen diferentes circuitos en un proceso CMOS de 180 nm: un regulador de baja caída de voltaje como unidad de gestión de energía, que proporciona una alimentación de 1.8 V estable, de bajo ruido, precisa e independiente de la carga para todo el sistema; amplificadores de instrumentación con una aproximación completamente diferencial, que incluyen una etapa de entrada de voltaje/corriente configurable, ganancia programable y ancho de banda ajustable, tanto en la frecuencia de corte baja como alta; un multiplicador para conformar la demodulación dual, que está embebido en el amplificador para optimizar consumo y área; y filtros pasa baja totalmente integrados, que actúan como extractores de magnitud de DC, con frecuencias de corte ajustables desde sub-Hz hasta cientos de Hz.<br /

Design and implementation of a multi-modal sensor with on-chip security

With the advancement of technology, wearable devices for fitness tracking, patient monitoring, diagnosis, and disease prevention are finding ways to be woven into modern world reality. CMOS sensors are known to be compact, with low power consumption, making them an inseparable part of wireless medical applications and Internet of Things (IoT). Digital/semi-digital output, by the translation of transmitting data into the frequency domain, takes advantages of both the analog and digital world. However, one of the most critical measures of communication, security, is ignored and not considered for fabrication of an integrated chip. With the advancement of Moore\u27s law and the possibility of having a higher number of transistors and more complex circuits, the feasibility of having on-chip security measures is drawing more attention. One of the fundamental means of secure communication is real-time encryption. Encryption/ciphering occurs when we encode a signal or data, and prevents unauthorized parties from reading or understanding this information. Encryption is the process of transmitting sensitive data securely and with privacy. This measure of security is essential since in biomedical devices, the attacker/hacker can endanger users of IoT or wearable sensors (e.g. attacks at implanted biosensors can cause fatal harm to the user). This work develops 1) A low power and compact multi-modal sensor that can measure temperature and impedance with a quasi-digital output and 2) a low power on-chip signal cipher for real-time data transfer

Interface Circuits for Microsensor Integrated Systems

ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Recent advances in sensing technologies, especially those for Microsensor Integrated Systems, have led to several new commercial applications. Among these, low voltage and low power circuit architectures have gained growing attention, being suitable for portable long battery life devices. The aim is to improve the performances of actual interface circuits and systems, both in terms of voltage mode and current mode, in order to overcome the potential problems due to technology scaling and different technology integrations. Related problems, especially those concerning parasitics, lead to a severe interface design attention, especially concerning the analog front-end and novel and smart architecture must be explored and tested, both at simulation and prototype level. Moreover, the growing demand for autonomous systems gets even harder the interface design due to the need of energy-aware cost-effective circuit interfaces integrating, where possible, energy harvesting solutions. The objective of this Special Issue is to explore the potential solutions to overcome actual limitations in sensor interface circuits and systems, especially those for low voltage and low power Microsensor Integrated Systems. The present Special Issue aims to present and highlight the advances and the latest novel and emergent results on this topic, showing best practices, implementations and applications. The Guest Editors invite to submit original research contributions dealing with sensor interfacing related to this specific topic. Additionally, application oriented and review papers are encouraged.

Electronics for Sensors

The aim of this Special Issue is to explore new advanced solutions in electronic systems and interfaces to be employed in sensors, describing best practices, implementations, and applications. The selected papers in particular concern photomultiplier tubes (PMTs) and silicon photomultipliers (SiPMs) interfaces and applications, techniques for monitoring radiation levels, electronics for biomedical applications, design and applications of time-to-digital converters, interfaces for image sensors, and general-purpose theory and topologies for electronic interfaces