1,135,295 research outputs found

    Current singularities at finitely compressible three-dimensional magnetic null points

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    The formation of current singularities at line-tied two- and three-dimensional (2D and 3D, respectively) magnetic null points in a nonresistive magnetohydrodynamic environment is explored. It is shown that, despite the different separatrix structures of 2D and 3D null points, current singularities may be initiated in a formally equivalent manner. This is true no matter whether the collapse is triggered by flux imbalance within closed, line-tied null points or driven by externally imposed velocity fields in open, incompressible geometries. A Lagrangian numerical code is used to investigate the finite amplitude perturbations that lead to singular current sheets in collapsing 2D and 3D null points. The form of the singular current distribution is analyzed as a function of the spatial anisotropy of the null point, and the effects of finite gas pressure are quantified. It is pointed out that the pressure force, while never stopping the formation of the singularity, significantly alters the morphology of the current distribution as well as dramatically weakening its strength. The impact of these findings on 2D and 3D magnetic reconnection models is discussed

    A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses

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    Background. Glioblastoma (GBM) is the most common primary brain tumor, with dismal prognosis. The failure of drug–radiation combinations with promising preclinical data to translate into effective clinical treatments may relate to the use of simplified 2-dimensional in vitro GBM cultures. Methods. We developed a customized 3D GBM culture system based on a polystyrene scaffold (Alvetex) that recapitulates key histological features of GBM and compared it with conventional 2D cultures with respect to their response to radiation and to molecular targeted agents for which clinical data are available. Results. In 3 patient-derived GBM lines, no difference in radiation sensitivity was observed between 2D and 3D cultures, as measured by clonogenic survival. Three different molecular targeted agents, for which robust clinical data are available were evaluated in 2D and 3D conditions: (i) temozolomide, which improves overall survival and is standard of care for GBM, exhibited statistically significant effects on clonogenic survival in both patient-derived cell lines when evaluated in the 3D model compared with only one cell line in 2D cells; (ii) bevacizumab, which has been shown to increase progression-free survival when added to standard chemoradiation in phase III clinical trials, exhibited marked radiosensitizing activity in our 3D model but had no effect on 2D cells; and (iii) erlotinib, which had no efficacy in clinical trials, displayed no activity in our 3D GBM model, but radiosensitized 2D cells. Conclusions. Our 3D model reliably predicted clinical efficacy, strongly supporting its clinical relevance and potential value in preclinical evaluation of drug–radiation combinations for GBM

    CLASP Constraints on the Magnetization and Geometrical Complexity of the Chromosphere-Corona Transition Region

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    The Chromospheric Lyman-Alpha Spectro-Polarimeter (CLASP) is a suborbital rocket experiment that on 3rd September 2015 measured the linear polarization produced by scattering processes in the hydrogen Ly-α\alpha line of the solar disk radiation, whose line-center photons stem from the chromosphere-corona transition region (TR). These unprecedented spectropolarimetric observations revealed an interesting surprise, namely that there is practically no center-to-limb variation (CLV) in the Q/IQ/I line-center signals. Using an analytical model, we first show that the geometrical complexity of the corrugated surface that delineates the TR has a crucial impact on the CLV of the Q/IQ/I and U/IU/I line-center signals. Secondly, we introduce a statistical description of the solar atmosphere based on a three-dimensional (3D) model derived from a state-of-the-art radiation magneto-hydrodynamic simulation. Each realization of the statistical ensemble is a 3D model characterized by a given degree of magnetization and corrugation of the TR, and for each such realization we solve the full 3D radiative transfer problem taking into account the impact of the CLASP instrument degradation on the calculated polarization signals. Finally, we apply the statistical inference method presented in a previous paper to show that the TR of the 3D model that produces the best agreement with the CLASP observations has a relatively weak magnetic field and a relatively high degree of corrugation. We emphasize that a suitable way to validate or refute numerical models of the upper solar chromosphere is by confronting calculations and observations of the scattering polarization in ultraviolet lines sensitive to the Hanle effect.Comment: Accepted for publication in The Astrophysical Journal Letter

    IRIS: A Generic Three-Dimensional Radiative Transfer Code

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    We present IRIS, a new generic three-dimensional (3D) spectral radiative transfer code that generates synthetic spectra, or images. It can be used as a diagnostic tool for comparison with astrophysical observations or laboratory astrophysics experiments. We have developed a 3D short-characteristic solver that works with a 3D nonuniform Cartesian grid. We have implemented a piecewise cubic, locally monotonic, interpolation technique that dramatically reduces the numerical diffusion effect. The code takes into account the velocity gradient effect resulting in gradual Doppler shifts of photon frequencies and subsequent alterations of spectral line profiles. It can also handle periodic boundary conditions. This first version of the code assumes Local Thermodynamic Equilibrium (LTE) and no scattering. The opacities and source functions are specified by the user. In the near future, the capabilities of IRIS will be extended to allow for non-LTE and scattering modeling. IRIS has been validated through a number of tests. We provide the results for the most relevant ones, in particular a searchlight beam test, a comparison with a 1D plane-parallel model, and a test of the velocity gradient effect. IRIS is a generic code to address a wide variety of astrophysical issues applied to different objects or structures, such as accretion shocks, jets in young stellar objects, stellar atmospheres, exoplanet atmospheres, accretion disks, rotating stellar winds, cosmological structures. It can also be applied to model laboratory astrophysics experiments, such as radiative shocks produced with high power lasers.Comment: accepted for publication in A&A; 17 pages, 9 figures, 2 table

    Distortion of Magnetic Fields in a Starless Core II: 3D Magnetic Field Structure of FeSt 1-457

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    Three dimensional (3D) magnetic field information on molecular clouds and cores is important for revealing their kinematical stability (magnetic support) against gravity which is fundamental for studying the initial conditions of star formation. In the present study, the 3D magnetic field structure of the dense starless core FeSt 1-457 is determined based on the near-infrared polarimetric observations of the dichroic polarization of background stars and simple 3D modeling. With an obtained angle of line-of-sight magnetic inclination axis θinc\theta_{\rm inc} of 45±1045^{\circ}\pm10^{\circ} and previously determined plane-of-sky magnetic field strength BpolB_{\rm pol} of 23.8±12.123.8\pm12.1 μG\mu{\rm G}, the total magnetic field strength for FeSt 1-457 is derived to be 33.7±18.033.7\pm18.0 μG\mu{\rm G}. The critical mass of FeSt 1-457, evaluated using both magnetic and thermal/turbulent support is Mcr=3.70±0.92{M}_{\rm cr} = 3.70\pm0.92 M{\rm M}_{\odot}, which is identical to the observed core mass, Mcore=3.55±0.75M_{\rm core}=3.55\pm0.75 M{\rm M}_{\odot}. We thus conclude that the stability of FeSt 1-457 is in a condition close to the critical state. Without infalling gas motion and no associated young stars, the core is regarded to be in the earliest stage of star formation, i.e., the stage just before the onset of dynamical collapse following the attainment of a supercritical condition. These properties would make FeSt 1-457 one of the best starless cores for future studies of the initial conditions of star formation.Comment: Accepted to the Astrophysical Journal (ApJ

    On Tetrahedralisations Containing Knotted and Linked Line Segments

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    This paper considers a set of twisted line segments in 3d such that they form a knot (a closed curve) or a link of two closed curves. Such line segments appear on the boundary of a family of 3d indecomposable polyhedra (like the Schönhardt polyhedron) whose interior cannot be tetrahedralised without additional vertices added. On the other hand, a 3d (non-convex) polyhedron whose boundary contains such line segments may still be decomposable as long as the twist is not too large. It is therefore interesting to consider the question: when there exists a tetrahedralisation contains a given set of knotted or linked line segments? In this paper, we studied a simplified question with the assumption that all vertices of the line segments are in convex position. It is straightforward to show that no tetrahedralisation of 6 vertices (the three-line-segments case) can contain a trefoil knot. Things become interesting when the number of line segments increases. Since it is necessary to create new interior edges to form a tetrahedralisation. We provided a detailed analysis for the case of a set of 4 line segments. This leads to a crucial condition on the orientation of pairs of new interior edges which determines whether this set is decomposable or not. We then prove a new theorem about the decomposability for a set of n (n ≥ 3) knotted or linked line segments. This theorem implies that the family of polyhedra generalised from the Schonhardt polyhedron by Rambau [1] are all indecomposable

    The three-dimensional structure of the Eta Carinae Homunculus

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    We investigate, using the modeling code SHAPE, the three-dimensional structure of the bipolar Homunculus nebula surrounding Eta Carinae, as mapped by new ESO VLT/X-Shooter observations of the H2 λ=2.12125\lambda=2.12125 micron emission line. Our results reveal for the first time important deviations from the axisymmetric bipolar morphology: 1) circumpolar trenches in each lobe positioned point-symmetrically from the center and 2) off-planar protrusions in the equatorial region from each lobe at longitudinal (~55 degrees) and latitudinal (10-20 degrees) distances from the projected apastron direction of the binary orbit. The angular distance between the protrusions (~110 degrees) is similar to the angular extent of each polar trench (~130 degrees) and nearly equal to the opening angle of the wind-wind collision cavity (~110 degrees). As in previous studies, we confirm a hole near the centre of each polar lobe and no detectable near-IR H2 emission from the thin optical skirt seen prominently in visible imagery. We conclude that the interaction between the outflows and/or radiation from the central binary stars and their orientation in space has had, and possibly still has, a strong influence on the Homunculus. This implies that prevailing theoretical models of the Homunculus are incomplete as most assume a single star origin that produces an axisymmetric nebula. We discuss how the newly found features might be related to the Homunculus ejection, the central binary and the interacting stellar winds. We also include a 3D printable version of our Homunculus model.Comment: 14 pages, 7 color figures, 1 interactive 3D figure (Figure 5, requires Adobe Reader), published in MNRAS. A 3D printable version of our Homunculus model can be downloaded from http://svs.gsfc.nasa.gov/vis/a010000/a011500/a011568/Eta_Car_Homunuculus_3D_model.zip or from the 'Supporting Information' link in the electronic version of the MNRAS articl
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