Hyperspectral colon tissue cell classification

A novel algorithm to discriminate between normal and malignant tissue cells of the human colon is presented. The microscopic level images of human colon tissue cells were acquired using hyperspectral imaging technology at contiguous wavelength intervals of visible light. While hyperspectral imagery data provides a wealth of information, its large size normally means high computational processing complexity. Several methods exist to avoid the so-called curse of dimensionality and hence reduce the computational complexity. In this study, we experimented with Principal Component Analysis (PCA) and two modifications of Independent Component Analysis (ICA). In the first stage of the algorithm, the extracted components are used to separate four constituent parts of the colon tissue: nuclei, cytoplasm, lamina propria, and lumen. The segmentation is performed in an unsupervised fashion using the nearest centroid clustering algorithm. The segmented image is further used, in the second stage of the classification algorithm, to exploit the spatial relationship between the labeled constituent parts. Experimental results using supervised Support Vector Machines (SVM) classification based on multiscale morphological features reveal the discrimination between normal and malignant tissue cells with a reasonable degree of accuracy

Improving acoustic vehicle classification by information fusion

We present an information fusion approach for ground vehicle classification based on the emitted acoustic signal. Many acoustic factors can contribute to the classification accuracy of working ground vehicles. Classification relying on a single feature set may lose some useful information if its underlying sound production model is not comprehensive. To improve classification accuracy, we consider an information fusion diagram, in which various aspects of an acoustic signature are taken into account and emphasized separately by two different feature extraction methods. The first set of features aims to represent internal sound production, and a number of harmonic components are extracted to characterize the factors related to the vehicle’s resonance. The second set of features is extracted based on a computationally effective discriminatory analysis, and a group of key frequency components are selected by mutual information, accounting for the sound production from the vehicle’s exterior parts. In correspondence with this structure, we further put forward a modifiedBayesian fusion algorithm, which takes advantage of matching each specific feature set with its favored classifier. To assess the proposed approach, experiments are carried out based on a data set containing acoustic signals from different types of vehicles. Results indicate that the fusion approach can effectively increase classification accuracy compared to that achieved using each individual features set alone. The Bayesian-based decision level fusion is found fusion is found to be improved than a feature level fusion approac

The Use of Features Extracted from Noisy Samples for Image Restoration Purposes

An important feature of neural networks is the ability they have to learn from their environment, and, through learning to improve performance in some sense. In the following we restrict the development to the problem of feature extracting unsupervised neural networks derived on the base of the biologically motivated Hebbian self-organizing principle which is conjectured to govern the natural neural assemblies and the classical principal component analysis (PCA) method used by statisticians for almost a century for multivariate data analysis and feature extraction. The research work reported in the paper aims to propose a new image reconstruction method based on the features extracted from the noise given by the principal components of the noise covariance matrix.feature extraction, PCA, Generalized Hebbian Algorithm, image restoration, wavelet transform, multiresolution support set

An automated pattern recognition system for the quantification of inflammatory cells in hepatitis-C-infected liver biopsies

This paper presents an automated system for the quantification of inflammatory cells in hepatitis-C-infected liver biopsies. Initially, features are extracted from colour-corrected biopsy images at positions of interest identified by adaptive thresholding and clump decomposition. A sequential floating search method and principal component analysis are used to reduce dimensionality. Manually annotated training images allow supervised training. The performance of Gaussian parametric and mixture models is compared when used to classify regions as either inflammatory or healthy. The system is optimized using a response surface method that maximises the area under the receiver operating characteristic curve. This system is then tested on images previously ranked by a number of observers with varying levels of expertise. These results are compared to the automated system using Spearman rank correlation. Results show that this system can rank 15 test images, with varying degrees of inflammation, in strong agreement with five expert pathologists