An Architecture forRepresenting Biological Processes based on Networks of Bio-inspired Processors

n this paper we propose the use of Networks of Bio-inspired Processors (NBP) to model some biological phenomena within a computational framework. In particular, we propose the use of an extension of NBP named Network Evolutionary Processors Transducers to simulate chemical transformations of substances. Within a biological process, chemical transformations of substances are basic operations in the change of the state of the cell. Previously, it has been proved that NBP are computationally complete, that is, they are able to solve NP complete problems in linear time, using massively parallel computations. In addition, we propose a multilayer architecture that will allow us to design models of biological processes related to cellular communication as well as their implications in the metabolic pathways. Subsequently, these models can be applied not only to biological-cellular instances but, possibly, also to configure instances of interactive processes in many other fields like population interactions, ecological trophic networks, in dustrial ecosystems, etc

Generating networks of genetic processors

[EN] The Networks of Genetic Processors (NGPs) are non-conventional models of computation based on genetic operations over strings, namely mutation and crossover operations as it was established in genetic algorithms. Initially, they have been proposed as acceptor machines which are decision problem solvers. In that case, it has been shown that they are universal computing models equivalent to Turing machines. In this work, we propose NGPs as enumeration devices and we analyze their computational power. First, we define the model and we propose its definition as parallel genetic algorithms. Once the correspondence between the two formalisms has been established, we carry out a study of the generation capacity of the NGPs under the research framework of the theory of formal languages. We investigate the relationships between the number of processors of the model and its generative power. Our results show that the number of processors is important to increase the generative capability of the model up to an upper bound, and that NGPs are universal models of computation if they are formulated as generation devices. This allows us to affirm that parallel genetic algorithms working under certain restrictions can be considered equivalent to Turing machines and, therefore, they are universal models of computation.This research was partially supported by TAILOR, a project funded by EU Horizon 2020 research and innovation programme under GA No 952215.Campos Frances, M.; Sempere Luna, JM. (2022). Generating networks of genetic processors. Genetic Programming and Evolvable Machines. 23(1):133-155. https://doi.org/10.1007/s10710-021-09423-713315523

Index to 1984 NASA Tech Briefs, volume 9, numbers 1-4

Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This index for 1984 Tech B Briefs contains abstracts and four indexes: subject, personal author, originating center, and Tech Brief Number. The following areas are covered: electronic components and circuits, electronic systems, physical sciences, materials, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences

Power system applications of fiber optics

Power system applications of optical systems, primarily using fiber optics, are reviewed. The first section reviews fibers as components of communication systems. The second section deals with fiber sensors for power systems, reviewing the many ways light sources and fibers can be combined to make measurements. Methods of measuring electric field gradient are discussed. Optical data processing is the subject of the third section, which begins by reviewing some widely different examples and concludes by outlining some potential applications in power systems: fault location in transformers, optical switching for light fired thyristors and fault detection based on the inherent symmetry of most power apparatus. The fourth and final section is concerned with using optical fibers to transmit power to electric equipment in a high voltage situation, potentially replacing expensive high voltage low power transformers. JPL has designed small photodiodes specifically for this purpose, and fabricated and tested several samples. This work is described

All-optical logic circuits based on the polarization properties of non-degenerate four-wave mixing

This thesis investigates a new class of all-optical logic circuits that are based on the polarization properties of non-degenerate Four-Wave Mixing. Such circuits would be used in conjunction with a data modulation format where the information is coded on the states of polarization of the electric field. Schemes to perform multiple triple-product logic functions are discussed and it is shown that higher-level Boolean operations involving several bits can be implemented without resorting to the standard 2-input gates that are based on some form of switching. Instead, an entire hierarchy of more complex Boolean functions can be derived based on the selection rules of multi-photon scattering processes that can form a new class of primitive building blocks for digital circuits. Possible applications of these circuits could involve some front-end signal processing to be performed all-optically in shared computer back-planes. As a simple illustration of this idea, a circuit performing error correction on a (3,1) Hamming Code is demonstrated. Error-free performance (Bit Error Rate of < 10^-9) at 2.5 Gbit/s is achieved after single-error correction on the Hamming word with 50 percent errors. The bit-rate is only limited by the bandwidth of available resources. Since Four-Wave Mixing is an ultrafast nonlinearity, these circuits offer the potential of computing at several terabits per second. Furthermore, it is shown that several Boolean functions can be performed in parallel in the same set of devices using different multi-photon scattering processes. The main objective of this thesis is to motivate a new paradigm of thought in digital circuit design. Challenges pertaining to the feasibility of these ideas are discusse

Real life applications of bio-inspired computing models: EAP and NEPs

Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Escuela Politécnica Superior, Departamento de Ingeniería Informática. Fecha de lectura: 04-07-201

Poly(A) RNA sequencing reveals age-related differences in the prefrontal cortex of dogs

Dogs may possess a unique translational potential to investigate neural aging and dementia because they are prone to age-related cognitive decline, including an Alzheimer’s disease–like pathological condition. Yet very little is known about the molecular mechanisms underlying canine cognitive decline. The goal of the current study was to explore the transcriptomic differences between young and old dogs’ frontal cortex, which is a brain region often affected by various forms of age-related dementia in humans. RNA isolates from the frontal cortical brain area of 13 pet dogs, which represented 7 different breeds and crossbreds, were analyzed. The dogs were euthanized for medical reasons, and their bodies had been donated by their owners for scientific purposes. The poly(A) tail RNA subfraction of the total transcriptome was targeted in the sequencing analysis. Cluster analyses, differential gene expression analyses, and gene ontology analyses were carried out to assess which genes and genetic regulatory mechanisms were mostly affected by aging. Age was the most prominent factor in the clustering of the animals, indicating the presence of distinct gene expression patterns related to aging in a genetically variable population. A total of 3436 genes were found to be differentially expressed between the age groups, many of which were linked to neural function, immune system, and protein synthesis. These findings are in accordance with previous human brain aging RNA sequencing studies. Some genes were found to behave more similarly to humans than to rodents, further supporting the applicability of dogs in translational aging research. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11357-022-00533-3