R-local Delaunay inhibition model

Let us consider the local specification system of Gibbs point process with inhib ition pairwise interaction acting on some Delaunay subgraph specifically not con taining the edges of Delaunay triangles with circumscribed circle of radius grea ter than some fixed positive real value $R$. Even if we think that there exists at least a stationary Gibbs state associated to such system, we do not know yet how to prove it mainly due to some uncontrolled "negative" contribution in the expression of the local energy needed to insert any number of points in some large enough empty region of the space. This is solved by introducing some subgraph, called the $R$-local Delaunay graph, which is a slight but tailored modification of the previous one. This kind of model does not inherit the local stability property but satisfies s ome new extension called $R$-local stability. This weakened property combined with the local property provides the existence o f Gibbs state.Comment: soumis \`{a} Journal of Statistical Physics 27 page

The dynamics of individual nucleosomes controls the chromatin condensation pathway: direct AFM visualization of variant chromatin

Chromatin organization and dynamics is studied in this work at scales ranging from single nucleosome to nucleosomal array by using a unique combination of biochemical assays, single molecule imaging technique and numerical modeling. We demonstrate that a subtle modification in the nucleosome structure induced by the histone variant H2A.Bbd drastically modifies the higher order organization of the nucleosomal arrays. Importantly, as directly visualized by AFM, conventional H2A nucleosomal arrays exhibit specific local organization, in contrast to H2A.Bbd arrays, which show "beads on a string" structure. The combination of systematic image analysis and theoretical modeling allows a quantitative description relating the observed gross structural changes of the arrays to their local organization. Our results strongly suggest that higher-order organization of H1-free nucleosomal arrays is mainly determined by the fluctuation properties of individual nucleosomes. Moreover, numerical simulations suggest the existence of attractive interactions between nucleosomes to provide the degree of compaction observed for conventional chromatin fibers.Comment: Biophys J. in pres

Asymmetric simple exclusion process on a ring conditioned on enhanced flux

We show that in the asymmetric simple exclusion process (ASEP) on a ring, conditioned on carrying a large flux, the particle experience an effective long-range potential which in the limit of very large flux takes the simple form $U= -2\sum_{i\neq j}\log|\sin\pi(n_{i}/L-n_{j}/L)|$, where $n_{1}n_{2},\ldots n_{N}$ are the particle positions, similar to the effective potential between the eigenvalues of the circular unitary ensemble in random matrices. Effective hopping rates and various quasistationary probabilities under such a conditioning are found analytically using the Bethe ansatz and determinantal free fermion techniques. Our asymptotic results extend to the limit of large current and large activity for a family of reaction-diffusion processes with on-site exclusion between particles. We point out an intriguing generic relation between classical stationary probability distributions for conditioned dynamics and quantum ground state wave functions, in particular, in the case of exclusion processes, for free fermions.Comment: submitted to J. Stat. Mec