A stochastic large deformation model for computational anatomy

In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for incorporating random variations into the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework. By accounting for randomness in a particular setup which is crafted to fit the geometrical properties of LDDMM, we formulate the template estimation problem for landmarks with noise and give two methods for efficiently estimating the parameters of the noise fields from a prescribed data set. One method directly approximates the time evolution of the variance of each landmark by a finite set of differential equations, and the other is based on an Expectation-Maximisation algorithm. In the second method, the evaluation of the data likelihood is achieved without registering the landmarks, by applying bridge sampling using a stochastically perturbed version of the large deformation gradient flow algorithm. The method and the estimation algorithms are experimentally validated on synthetic examples and shape data of human corpora callosa

Planogram Compliance Checking Based on Detection of Recurring Patterns

In this paper, a novel method for automatic planogram compliance checking in retail chains is proposed without requiring product template images for training. Product layout is extracted from an input image by means of unsupervised recurring pattern detection and matched via graph matching with the expected product layout specified by a planogram to measure the level of compliance. A divide and conquer strategy is employed to improve the speed. Specifically, the input image is divided into several regions based on the planogram. Recurring patterns are detected in each region respectively and then merged together to estimate the product layout. Experimental results on real data have verified the efficacy of the proposed method. Compared with a template-based method, higher accuracies are achieved by the proposed method over a wide range of products.Comment: Accepted by MM (IEEE Multimedia Magazine) 201

Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates

The study of cerebral anatomy in developing neonates is of great importance for the understanding of brain development during the early period of life. This dissertation therefore focuses on three challenges in the modelling of cerebral anatomy in neonates during brain development. The methods that have been developed all use Magnetic Resonance Images (MRI) as source data. To facilitate study of vascular development in the neonatal period, a set of image analysis algorithms are developed to automatically extract and model cerebral vessel trees. The whole process consists of cerebral vessel tracking from automatically placed seed points, vessel tree generation, and vasculature registration and matching. These algorithms have been tested on clinical Time-of- Flight (TOF) MR angiographic datasets. To facilitate study of the neonatal cortex a complete cerebral cortex segmentation and reconstruction pipeline has been developed. Segmentation of the neonatal cortex is not effectively done by existing algorithms designed for the adult brain because the contrast between grey and white matter is reversed. This causes pixels containing tissue mixtures to be incorrectly labelled by conventional methods. The neonatal cortical segmentation method that has been developed is based on a novel expectation-maximization (EM) method with explicit correction for mislabelled partial volume voxels. Based on the resulting cortical segmentation, an implicit surface evolution technique is adopted for the reconstruction of the cortex in neonates. The performance of the method is investigated by performing a detailed landmark study. To facilitate study of cortical development, a cortical surface registration algorithm for aligning the cortical surface is developed. The method first inflates extracted cortical surfaces and then performs a non-rigid surface registration using free-form deformations (FFDs) to remove residual alignment. Validation experiments using data labelled by an expert observer demonstrate that the method can capture local changes and follow the growth of specific sulcus

Investigating Full-Waveform Lidar Data for Detection and Recognition of Vertical Objects

A recent innovation in commercially-available topographic lidar systems is the ability to record return waveforms at high sampling frequencies. These “full-waveform” systems provide up to two orders of magnitude more data than “discrete-return” systems. However, due to the relatively limited capabilities of current processing and analysis software, more data does not always translate into more or better information for object extraction applications. In this paper, we describe a new approach for exploiting full waveform data to improve detection and recognition of vertical objects, such as trees, poles, buildings, towers, and antennas. Each waveform is first deconvolved using an expectation-maximization (EM) algorithm to obtain a train of spikes in time, where each spike corresponds to an individual laser reflection. The output is then georeferenced to create extremely dense, detailed X,Y,Z,I point clouds, where I denotes intensity. A tunable parameter is used to control the number of spikes in the deconvolved waveform, and, hence, the point density of the output point cloud. Preliminary results indicate that the average number of points on vertical objects using this method is several times higher than using discrete-return lidar data. The next steps in this ongoing research will involve voxelizing the lidar point cloud to obtain a high-resolution volume of intensity values and computing a 3D wavelet representation. The final step will entail performing vertical object detection/recognition in the wavelet domain using a multiresolution template matching approach