Thoracic Disease Identification and Localization with Limited Supervision

Accurate identification and localization of abnormalities from radiology images play an integral part in clinical diagnosis and treatment planning. Building a highly accurate prediction model for these tasks usually requires a large number of images manually annotated with labels and finding sites of abnormalities. In reality, however, such annotated data are expensive to acquire, especially the ones with location annotations. We need methods that can work well with only a small amount of location annotations. To address this challenge, we present a unified approach that simultaneously performs disease identification and localization through the same underlying model for all images. We demonstrate that our approach can effectively leverage both class information as well as limited location annotation, and significantly outperforms the comparative reference baseline in both classification and localization tasks.Comment: Conference on Computer Vision and Pattern Recognition 2018 (CVPR 2018). V1: CVPR submission; V2: +supplementary; V3: CVPR camera-ready; V4: correction, update reference baseline results according to their latest post; V5: minor correction; V6: Identification results using NIH data splits and various image model

Stratified decision forests for accurate anatomical landmark localization in cardiac images

Accurate localization of anatomical landmarks is an important step in medical imaging, as it provides useful prior information for subsequent image analysis and acquisition methods. It is particularly useful for initialization of automatic image analysis tools (e.g. segmentation and registration) and detection of scan planes for automated image acquisition. Landmark localization has been commonly performed using learning based approaches, such as classifier and/or regressor models. However, trained models may not generalize well in heterogeneous datasets when the images contain large differences due to size, pose and shape variations of organs. To learn more data-adaptive and patient specific models, we propose a novel stratification based training model, and demonstrate its use in a decision forest. The proposed approach does not require any additional training information compared to the standard model training procedure and can be easily integrated into any decision tree framework. The proposed method is evaluated on 1080 3D highresolution and 90 multi-stack 2D cardiac cine MR images. The experiments show that the proposed method achieves state-of-theart landmark localization accuracy and outperforms standard regression and classification based approaches. Additionally, the proposed method is used in a multi-atlas segmentation to create a fully automatic segmentation pipeline, and the results show that it achieves state-of-the-art segmentation accuracy

A Review of Codebook Models in Patch-Based Visual Object Recognition

The codebook model-based approach, while ignoring any structural aspect in vision, nonetheless provides state-of-the-art performances on current datasets. The key role of a visual codebook is to provide a way to map the low-level features into a fixed-length vector in histogram space to which standard classifiers can be directly applied. The discriminative power of such a visual codebook determines the quality of the codebook model, whereas the size of the codebook controls the complexity of the model. Thus, the construction of a codebook is an important step which is usually done by cluster analysis. However, clustering is a process that retains regions of high density in a distribution and it follows that the resulting codebook need not have discriminant properties. This is also recognised as a computational bottleneck of such systems. In our recent work, we proposed a resource-allocating codebook, to constructing a discriminant codebook in a one-pass design procedure that slightly outperforms more traditional approaches at drastically reduced computing times. In this review we survey several approaches that have been proposed over the last decade with their use of feature detectors, descriptors, codebook construction schemes, choice of classifiers in recognising objects, and datasets that were used in evaluating the proposed methods