MildInt: Deep Learning-Based Multimodal Longitudinal Data Integration Framework

As large amounts of heterogeneous biomedical data become available, numerous methods for integrating such datasets have been developed to extract complementary knowledge from multiple domains of sources. Recently, a deep learning approach has shown promising results in a variety of research areas. However, applying the deep learning approach requires expertise for constructing a deep architecture that can take multimodal longitudinal data. Thus, in this paper, a deep learning-based python package for data integration is developed. The python package deep learning-based multimodal longitudinal data integration framework (MildInt) provides the preconstructed deep learning architecture for a classification task. MildInt contains two learning phases: learning feature representation from each modality of data and training a classifier for the final decision. Adopting deep architecture in the first phase leads to learning more task-relevant feature representation than a linear model. In the second phase, linear regression classifier is used for detecting and investigating biomarkers from multimodal data. Thus, by combining the linear model and the deep learning model, higher accuracy and better interpretability can be achieved. We validated the performance of our package using simulation data and real data. For the real data, as a pilot study, we used clinical and multimodal neuroimaging datasets in Alzheimer's disease to predict the disease progression. MildInt is capable of integrating multiple forms of numerical data including time series and non-time series data for extracting complementary features from the multimodal dataset

Learning Social Image Embedding with Deep Multimodal Attention Networks

Learning social media data embedding by deep models has attracted extensive research interest as well as boomed a lot of applications, such as link prediction, classification, and cross-modal search. However, for social images which contain both link information and multimodal contents (e.g., text description, and visual content), simply employing the embedding learnt from network structure or data content results in sub-optimal social image representation. In this paper, we propose a novel social image embedding approach called Deep Multimodal Attention Networks (DMAN), which employs a deep model to jointly embed multimodal contents and link information. Specifically, to effectively capture the correlations between multimodal contents, we propose a multimodal attention network to encode the fine-granularity relation between image regions and textual words. To leverage the network structure for embedding learning, a novel Siamese-Triplet neural network is proposed to model the links among images. With the joint deep model, the learnt embedding can capture both the multimodal contents and the nonlinear network information. Extensive experiments are conducted to investigate the effectiveness of our approach in the applications of multi-label classification and cross-modal search. Compared to state-of-the-art image embeddings, our proposed DMAN achieves significant improvement in the tasks of multi-label classification and cross-modal search

BLOCK: Bilinear Superdiagonal Fusion for Visual Question Answering and Visual Relationship Detection

Multimodal representation learning is gaining more and more interest within the deep learning community. While bilinear models provide an interesting framework to find subtle combination of modalities, their number of parameters grows quadratically with the input dimensions, making their practical implementation within classical deep learning pipelines challenging. In this paper, we introduce BLOCK, a new multimodal fusion based on the block-superdiagonal tensor decomposition. It leverages the notion of block-term ranks, which generalizes both concepts of rank and mode ranks for tensors, already used for multimodal fusion. It allows to define new ways for optimizing the tradeoff between the expressiveness and complexity of the fusion model, and is able to represent very fine interactions between modalities while maintaining powerful mono-modal representations. We demonstrate the practical interest of our fusion model by using BLOCK for two challenging tasks: Visual Question Answering (VQA) and Visual Relationship Detection (VRD), where we design end-to-end learnable architectures for representing relevant interactions between modalities. Through extensive experiments, we show that BLOCK compares favorably with respect to state-of-the-art multimodal fusion models for both VQA and VRD tasks. Our code is available at https://github.com/Cadene/block.bootstrap.pytorch