Analysis of Dynamic Brain Imaging Data

Modern imaging techniques for probing brain function, including functional Magnetic Resonance Imaging, intrinsic and extrinsic contrast optical imaging, and magnetoencephalography, generate large data sets with complex content. In this paper we develop appropriate techniques of analysis and visualization of such imaging data, in order to separate the signal from the noise, as well as to characterize the signal. The techniques developed fall into the general category of multivariate time series analysis, and in particular we extensively use the multitaper framework of spectral analysis. We develop specific protocols for the analysis of fMRI, optical imaging and MEG data, and illustrate the techniques by applications to real data sets generated by these imaging modalities. In general, the analysis protocols involve two distinct stages: `noise' characterization and suppression, and `signal' characterization and visualization. An important general conclusion of our study is the utility of a frequency-based representation, with short, moving analysis windows to account for non-stationarity in the data. Of particular note are (a) the development of a decomposition technique (`space-frequency singular value decomposition') that is shown to be a useful means of characterizing the image data, and (b) the development of an algorithm, based on multitaper methods, for the removal of approximately periodic physiological artifacts arising from cardiac and respiratory sources.Comment: 40 pages; 26 figures with subparts including 3 figures as .gif files. Originally submitted to the neuro-sys archive which was never publicly announced (was 9804003

Fractional biorthogonal partners in channel equalization and signal interpolation

The concept of biorthogonal partners has been introduced recently by the authors. The work presented here is an extension of some of these results to the case where the upsampling and downsampling ratios are not integers but rational numbers, hence, the name fractional biorthogonal partners. The conditions for the existence of stable and of finite impulse response (FIR) fractional biorthogonal partners are derived. It is also shown that the FIR solutions (when they exist) are not unique. This property is further explored in one of the applications of fractional biorthogonal partners, namely, the fractionally spaced equalization in digital communications. The goal is to construct zero-forcing equalizers (ZFEs) that also combat the channel noise. The performance of these equalizers is assessed through computer simulations. Another application considered is the all-FIR interpolation technique with the minimum amount of oversampling required in the input signal. We also consider the extension of the least squares approximation problem to the setting of fractional biorthogonal partners

Communication Theoretic Data Analytics

Widespread use of the Internet and social networks invokes the generation of big data, which is proving to be useful in a number of applications. To deal with explosively growing amounts of data, data analytics has emerged as a critical technology related to computing, signal processing, and information networking. In this paper, a formalism is considered in which data is modeled as a generalized social network and communication theory and information theory are thereby extended to data analytics. First, the creation of an equalizer to optimize information transfer between two data variables is considered, and financial data is used to demonstrate the advantages. Then, an information coupling approach based on information geometry is applied for dimensionality reduction, with a pattern recognition example to illustrate the effectiveness. These initial trials suggest the potential of communication theoretic data analytics for a wide range of applications.Comment: Published in IEEE Journal on Selected Areas in Communications, Jan. 201