Deep learning assisted MRI guided attenuation correction in PET

This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University LondonPositron emission tomography (PET) is a unique imaging modality that provides physiological and functional details of the tissue at the molecular level. However, the acquired PET images have some limitations such as the attenuation. PET attenuation correction is an essential step to obtain the full potential of PET quantification. With the wide use of hybrid PET/MR scanners, magnetic resonance (MR) images are used to address the problem of PET attenuation correction. The MR images segmentation is one simple and robust approach to create pseudo computed tomography (CT) images, which are used to generate attenuation coefficient maps to correct the PET attenuation. Recently, deep learning has been proposed and used as a promising technique to efficiently perform MR and various medical images segmentation. In this research work, deep learning guided segmentation approaches have been proposed to enhance the bone class segmentation of MR brain images in order to generate accurate pseudo-CT images. The first approach has introduced the combination of handcrafted features with deep learning features to enrich the set of features. Multiresolution analysis techniques, which generate multiscale and multidirectional coefficients of an image such as contourlet and shearlet transforms, are applied and combined with deep convolutional neural network (CNN) features. Different experiments have been conducted to investigate the number of selected coefficients and the insertion location of the handcrafted features. The second approach aims at reducing the segmentation algorithm’s complexity while maintaining the segmentation performance. An attention based convolutional encode-decoder network has been proposed to adaptively recalibrate the deep network features. This attention based network consists of two different squeeze and excitation blocks that excite the features spatially and channel wise. The two blocks are combined sequentially to decrease the number of network’s parameters and reduces the model complexity. The third approach has been focuses on the application of transfer learning from different MR sequences such as T1 weighted (T1-w) and T2 weighted (T2-w) images. A pretrained model with T1-w MR sequences is fine tuned to perform the segmentation of T2-w images. Multiple fine tuning approaches and experiments have been conducted to study the best fine tuning mechanism that is able to build an efficient segmentation model for both T1-w and T2-w segmentation. Clinical datasets of fifty patients with different conditions and diagnosis have been used to carry an objective evaluation to measure the segmentation performance of the results obtained by the three proposed methods. The first and second approaches have been validated with other studies in the literature that applied deep network based segmentation technique to perform MR based attenuation correction for PET images. The proposed methods have shown an enhancement in the bone segmentation with an increase of dice similarity coefficient (DSC) from 0.6179 to 0.6567 using an ensemble of CNNs with an improvement percentage of 6.3%. The proposed excitation-based CNN has decreased the model complexity by decreasing the number of trainable parameters by more than 46% where less computing resources are required to train the model. The proposed hybrid transfer learning method has shown its superiority to build a multi-sequences (T1-w and T2-w) segmentation approach compared to other applied transfer learning methods especially with the bone class where the DSC is increased from 0.3841 to 0.5393. Moreover, the hybrid transfer learning approach requires less computing time than transfer learning using open and conservative fine tuning

Advances in Deep Learning Towards Fire Emergency Application : Novel Architectures, Techniques and Applications of Neural Networks

Paper IV is not published yet.With respect to copyright paper IV and paper VI was excluded from the dissertation.Deep Learning has been successfully used in various applications, and recently, there has been an increasing interest in applying deep learning in emergency management. However, there are still many significant challenges that limit the use of deep learning in the latter application domain. In this thesis, we address some of these challenges and propose novel deep learning methods and architectures. The challenges we address fall in these three areas of emergency management: Detection of the emergency (fire), Analysis of the situation without human intervention and finally Evacuation Planning. In this thesis, we have used computer vision tasks of image classification and semantic segmentation, as well as sound recognition, for detection and analysis. For evacuation planning, we have used deep reinforcement learning.publishedVersio

Deep learning in food category recognition

Integrating artificial intelligence with food category recognition has been a field of interest for research for the past few decades. It is potentially one of the next steps in revolutionizing human interaction with food. The modern advent of big data and the development of data-oriented fields like deep learning have provided advancements in food category recognition. With increasing computational power and ever-larger food datasets, the approach’s potential has yet to be realized. This survey provides an overview of methods that can be applied to various food category recognition tasks, including detecting type, ingredients, quality, and quantity. We survey the core components for constructing a machine learning system for food category recognition, including datasets, data augmentation, hand-crafted feature extraction, and machine learning algorithms. We place a particular focus on the field of deep learning, including the utilization of convolutional neural networks, transfer learning, and semi-supervised learning. We provide an overview of relevant studies to promote further developments in food category recognition for research and industrial applicationsMRC (MC_PC_17171)Royal Society (RP202G0230)BHF (AA/18/3/34220)Hope Foundation for Cancer Research (RM60G0680)GCRF (P202PF11)Sino-UK Industrial Fund (RP202G0289)LIAS (P202ED10Data Science Enhancement Fund (P202RE237)Fight for Sight (24NN201);Sino-UK Education Fund (OP202006)BBSRC (RM32G0178B8

Advances in Object and Activity Detection in Remote Sensing Imagery

The recent revolution in deep learning has enabled considerable development in the fields of object and activity detection. Visual object detection tries to find objects of target classes with precise localisation in an image and assign each object instance a corresponding class label. At the same time, activity recognition aims to determine the actions or activities of an agent or group of agents based on sensor or video observation data. It is a very important and challenging problem to detect, identify, track, and understand the behaviour of objects through images and videos taken by various cameras. Together, objects and their activity recognition in imaging data captured by remote sensing platforms is a highly dynamic and challenging research topic. During the last decade, there has been significant growth in the number of publications in the field of object and activity recognition. In particular, many researchers have proposed application domains to identify objects and their specific behaviours from air and spaceborne imagery. This Special Issue includes papers that explore novel and challenging topics for object and activity detection in remote sensing images and videos acquired by diverse platforms

Machine Learning Methods for Image Analysis in Medical Applications, from Alzheimer\u27s Disease, Brain Tumors, to Assisted Living

Healthcare has progressed greatly nowadays owing to technological advances, where machine learning plays an important role in processing and analyzing a large amount of medical data. This thesis investigates four healthcare-related issues (Alzheimer\u27s disease detection, glioma classification, human fall detection, and obstacle avoidance in prosthetic vision), where the underlying methodologies are associated with machine learning and computer vision. For Alzheimer’s disease (AD) diagnosis, apart from symptoms of patients, Magnetic Resonance Images (MRIs) also play an important role. Inspired by the success of deep learning, a new multi-stream multi-scale Convolutional Neural Network (CNN) architecture is proposed for AD detection from MRIs, where AD features are characterized in both the tissue level and the scale level for improved feature learning. Good classification performance is obtained for AD/NC (normal control) classification with test accuracy 94.74%. In glioma subtype classification, biopsies are usually needed for determining different molecular-based glioma subtypes. We investigate non-invasive glioma subtype prediction from MRIs by using deep learning. A 2D multi-stream CNN architecture is used to learn the features of gliomas from multi-modal MRIs, where the training dataset is enlarged with synthetic brain MRIs generated by pairwise Generative Adversarial Networks (GANs). Test accuracy 88.82% has been achieved for IDH mutation (a molecular-based subtype) prediction. A new deep semi-supervised learning method is also proposed to tackle the problem of missing molecular-related labels in training datasets for improving the performance of glioma classification. In other two applications, we also address video-based human fall detection by using co-saliency-enhanced Recurrent Convolutional Networks (RCNs), as well as obstacle avoidance in prosthetic vision by characterizing obstacle-related video features using a Spiking Neural Network (SNN). These investigations can benefit future research, where artificial intelligence/deep learning may open a new way for real medical applications

Advanced Fault Diagnosis and Health Monitoring Techniques for Complex Engineering Systems

Over the last few decades, the field of fault diagnostics and structural health management has been experiencing rapid developments. The reliability, availability, and safety of engineering systems can be significantly improved by implementing multifaceted strategies of in situ diagnostics and prognostics. With the development of intelligence algorithms, smart sensors, and advanced data collection and modeling techniques, this challenging research area has been receiving ever-increasing attention in both fundamental research and engineering applications. This has been strongly supported by the extensive applications ranging from aerospace, automotive, transport, manufacturing, and processing industries to defense and infrastructure industries