195 research outputs found
TelsNet: temporal lesion network embedding in a transformer model to detect cervical cancer through colposcope images
Cervical cancer ranks as the fourth most prevalent malignancy among women globally. Timely identification and intervention in cases of cervical cancer hold the potential for achieving complete remission and cure. In this study, we built a deep learning model based on self-attention mechanism using transformer architecture to classify the cervix images to help in diagnosis of cervical cancer. We have used techniques like an enhanced multivariate gaussian mixture model optimized with mexican axolotl algorithm for segmenting the colposcope images prior to the Temporal Lesion Convolution Neural Network (TelsNet) classifying the images. TelsNet is a transformer-based neural network that uses temporal convolutional neural networks to identify cancerous regions in colposcope images. Our experiments show that TelsNet achieved an accuracy of 92.7%, with a sensitivity of 73.4% and a specificity of 82.1%. We compared the performance of our model with various state-of-the-art methods, and our results demonstrate that TelsNet outperformed the other methods. The findings have the potential to significantly simplify the process of detecting and accurately classifying cervical cancers at an early stage, leading to improved rates of remission and better overall outcomes for patients globally
Data fusion techniques for biomedical informatics and clinical decision support
Data fusion can be used to combine multiple data sources or modalities to facilitate enhanced visualization, analysis, detection, estimation, or classification. Data fusion can be applied at the raw-data, feature-based, and decision-based levels. Data fusion applications of different sorts have been built up in areas such as statistics, computer vision and other machine learning aspects. It has been employed in a variety of realistic scenarios such as medical diagnosis, clinical decision support, and structural health monitoring. This dissertation includes investigation and development of methods to perform data fusion for cervical cancer intraepithelial neoplasia (CIN) and a clinical decision support system. The general framework for these applications includes image processing followed by feature development and classification of the detected region of interest (ROI). Image processing methods such as k-means clustering based on color information, dilation, erosion and centroid locating methods were used for ROI detection. The features extracted include texture, color, nuclei-based and triangle features. Analysis and classification was performed using feature- and decision-level data fusion techniques such as support vector machine, statistical methods such as logistic regression, linear discriminant analysis and voting algorithms --Abstract, page iv
Edge-variational Graph Convolutional Networks for Uncertainty-aware Disease Prediction
There is a rising need for computational models that can complementarily
leverage data of different modalities while investigating associations between
subjects for population-based disease analysis. Despite the success of
convolutional neural networks in representation learning for imaging data, it
is still a very challenging task. In this paper, we propose a generalizable
framework that can automatically integrate imaging data with non-imaging data
in populations for uncertainty-aware disease prediction. At its core is a
learnable adaptive population graph with variational edges, which we
mathematically prove that it is optimizable in conjunction with graph
convolutional neural networks. To estimate the predictive uncertainty related
to the graph topology, we propose the novel concept of Monte-Carlo edge
dropout. Experimental results on four databases show that our method can
consistently and significantly improve the diagnostic accuracy for Autism
spectrum disorder, Alzheimer's disease, and ocular diseases, indicating its
generalizability in leveraging multimodal data for computer-aided diagnosis.Comment: Accepted to MICCAI 202
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