16,042 research outputs found
Strategic perspectives on modularity
In this paper we argue that the debate on modularity has come to a point where a consensus is slowly emerging. However, we also contend that this consensus is clearly technology driven. In particular, no room is left for firm strategies. Typically, technology is considered as an exogenous variable to which firms have no choices but to adapt. Taking a slightly different perspective, our main objective is to offer a conceptual framework enabling to shed light on the role of corporate strategies in the process of modularization. From interviews with academic design engineers, we show that firms often consider product architecture as a critical variable to fit their strategic requirements. Based on design sciences, we build an original approach to product modularity. This approach, which leaves an important space for firms' strategic choices, proves also to seize a large part of the industrial reality of modularity. Our framework, which is a first step towards the consideration of strategies within the framework of modularity, gives an account for the diversity of industrial logics related to product modularization.product modularity ; corporate strategy ; technological determinism
Desiderata for domain reference ontologies in biomedicine
AbstractDomain reference ontologies represent knowledge about a particular part of the world in a way that is independent from specific objectives, through a theory of the domain. An example of reference ontology in biomedical informatics is the Foundational Model of Anatomy (FMA), an ontology of anatomy that covers the entire range of macroscopic, microscopic, and subcellular anatomy. The purpose of this paper is to explore how two domain reference ontologiesâthe FMA and the Chemical Entities of Biological Interest (ChEBI) ontology, can be used (i) to align existing terminologies, (ii) to infer new knowledge in ontologies of more complex entities, and (iii) to manage and help reasoning about individual data. We analyze those kinds of usages of these two domain reference ontologies and suggest desiderata for reference ontologies in biomedicine. While a number of groups and communities have investigated general requirements for ontology design and desiderata for controlled medical vocabularies, we are focusing on application purposes. We suggest five desirable characteristics for reference ontologies: good lexical coverage, good coverage in terms of relations, compatibility with standards, modularity, and ability to represent variation in reality
Flora robotica -- An Architectural System Combining Living Natural Plants and Distributed Robots
Key to our project flora robotica is the idea of creating a bio-hybrid system
of tightly coupled natural plants and distributed robots to grow architectural
artifacts and spaces. Our motivation with this ground research project is to
lay a principled foundation towards the design and implementation of living
architectural systems that provide functionalities beyond those of orthodox
building practice, such as self-repair, material accumulation and
self-organization. Plants and robots work together to create a living organism
that is inhabited by human beings. User-defined design objectives help to steer
the directional growth of the plants, but also the system's interactions with
its inhabitants determine locations where growth is prohibited or desired
(e.g., partitions, windows, occupiable space). We report our plant species
selection process and aspects of living architecture. A leitmotif of our
project is the rich concept of braiding: braids are produced by robots from
continuous material and serve as both scaffolds and initial architectural
artifacts before plants take over and grow the desired architecture. We use
light and hormones as attraction stimuli and far-red light as repelling
stimulus to influence the plants. Applied sensors range from simple proximity
sensing to detect the presence of plants to sophisticated sensing technology,
such as electrophysiology and measurements of sap flow. We conclude by
discussing our anticipated final demonstrator that integrates key features of
flora robotica, such as the continuous growth process of architectural
artifacts and self-repair of living architecture.Comment: 16 pages, 12 figure
Cosmotic, Aquatic. Exploring the potential of computational design in the preservation of aquatic ecotones
This paper looks at the possible role of computational design ecologically in the fight against the loss of the aquatic Ecotone. As climate change keeps altering all the natural aspects of our planet, and as our kind continues to sabotage its ecologies, coral reefs come in focus. Aquatically, coral reefs count as a fertile zone for biodiversity. Usually being the Ecotone between land and sea, these barriers host many species and riches. However, due to the excessive abuse caused by human activity be it world-wide pollution or direct human contact, these reefs are constantly bleaching and breaking. In 2016, the Architecture Association gathered a group of international architecture students and professionals in a visiting school in Jordan titled âHyperbolic Reefsâ looking at the possibility of recruiting new computational methods to preserve and possibly regenerate the Ecotone. It was considered that new simulation techniques along with parametric design could contribute into the assessment and prevention of the catastrophic results.
The two-week event was divided into chapters and was initiated by a series of lectures and discussions conducted by worldwide leading architects and experts who presented an important material to build upon. Then, the participants underwent a site visit to the coral reef of Al-Aqaba, collecting data, samples and media and recording insights and local testimonies. The third step of the experience was to assimilate the material and data and discuss openly the ways that computation could lead to a better coral life. Several software and tools were assigned to produce a design that would help attenuate the compromise of the coral reef through computation. An archive of data was produced and exhibited to the public.
The results of this brief exercise was a number of suggestions and future aspirations triggered solely towards revitalizing the Ecotone. Issues such as the abundance of irresponsible snorkeling and diving, many governmentsâ indifferent policies towards the coral reefs, global warming, climate change, coral bleaching and aquatic architecture were confronted through parametric projects ranging from purely architectural to abstract human capsules. Computational tools allowed the reproduction of the whole system digitally, the precise tracing of the coralsâ patterns, dimensions and colors, simulation software predicted the role of light and heat in certain zones, and parametric programs provided an incomparable flexibility in the designing process, going completely in sync with the fragile and intricate aspect of a coral unit. 3D printing was also an integral factor in the presentation and study of the presented models.
This studyâs scope was to expand the use of computation in a theoretical way to reach new and creative prospects, and to raise awareness to the situation of the coral reef and the risks facing its degradation
On the foundations of cancer modelling: selected topics, speculations, & perspectives
This paper presents a critical review of selected topics related to the modelling of cancer onset, evolution and growth, with the aim of illustrating, to a wide applied mathematical readership, some of the novel mathematical problems in the field. This review attempts to capture, from the appropriate literature, the main issues involved in the modelling of phenomena related to cancer dynamics at all scales which characterise this highly complex system: from the molecular scale up to that of tissue. The last part of the paper discusses the challenge of developing a mathematical biological theory of tumour onset and evolution
Opportunities for Dutch Biorefineries
Deze Roadmap Bioraffinage beschrijft een aantal mogelijke routes naar de ontwikkeling en implementatie van een bioraffinage-gerelateerde Bio-based Economy in Nederland. De Roadmap combineert korte- en middellange termijn mogelijkheden (commerciĂŤle implementatie, demonstratie plants, pilot plants en gerelateerd toegepast onderzoek) met strategisch onderzoek voor de langere termijn. Tevens zijn vier z.g. Moonshots uitgewerkt, als voorziene bioraffinagestrategieĂŤn met een grote potentie voor de Nederlandse economi
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