Reconciling scientific approaches for organic farming research: Part I- Reflection on research methods in organic grassland and animal production at the Louis Bolk Institute, The Netherlands

This dissertation focuses on the research question: what is peculiar to agricultural research when its purpose is to support the conscious development of organic agriculture?What approaches, designs and methods are used for such research? Since the 1990s the Louis Bolk Institute has become one of the important actors in the field of organic research and development. The author analysed the methodological aspects of seven case studies,each following the same format: background of the project, methods used, a reflection on the methods and, to a limited extent, agronomic results. Each of these sheds light on an aspect of the Louis Bolk Institute’s approach to research. Organic farming is experienced as a new paradigm and its research methods need to do justice to it. Three criteria were formulated for this purpose: the self regulation of farming systems, the involvement of farmers and the respect for the integrity of life. Two conceptual frameworks are used to analyse the research methods: (1) a four-quadrant matrix. Epistemological, ontological and methodological changes in the way of thinking are relevant in discussions about holism versus reductionism and positivism versus constructivism. The second framework is (2) a triangle which can show the relationship between the underlying values, the involvement of the actors and the nature of the scientific process. The scientific position which is defended in this dissertation can ultimately best be described as a ‘radical holistic research strategy’. Research approaches applied in the case studies are: interdisciplinary search, experiential science and mutual learning, farmer-to-farmer learning, exploring tacit knowledge, bio-ethical evaluation, Goethean science and systemic development. In the four quadrant matrix two new additional research methods are positioned: (1) Goethean science is included as a holistic counterpart to multidisciplinary system ecology; (2) experiential science is included for comparison with mono-disciplinary experimental research. The constructivist character of both Goethean science and experiential science particularly distinguishes these methods from mainstream science. The meta-reflection on the research showed some important new elements of research. There was a systemic orientation in terms of a cohesive set of management measures and actions. This systemic orientation also encompasses holism in terms of Goethean science. In addition there is the experiential science based on intuitive action and pattern recognition.The reflection on the methods made it clear that their acceptance was influenced by the underlying scientific philosophy. The entire research strategy is thus based on two different interpretations of knowledge. Experiential science focuses on the actions of the farmer and is based on the epistemology of action. In addition there is an epistemology of knowledge, where it relates to interdisciplinary research and Goethean science. There are barriers to the acceptance of these scientific methods in the current lack of suitable statistical evaluation methods,and also in the absence of accepted methods for explicitly exploring reality as constructed by people

A meta-framework for sustainability assessment

This paper addresses the distinction between integrated assessment and sustainability assessment (SA), and, using a systemic approach, outlines how to move from integrated assessment to SA. The fundamental differences may be identified at three levels: ontological, methodological and epistemological. We present a novel methodological framework for SA, based on a literature meta-review of multi-scale and multi-purpose appraisal methodologies and related methods, models, and indicators. SA is considered as a structured procedure encompassing different field-specific analytical methods and models, depending on the specific application and decision context. External inputs to the methodology are the “values” to be considered in the analysis and the (political) boundaries defined for them, including also the sustainability framework in which the analysis is carried out . Internal elements of the methodology comprise the choice of the approach (e.g. “what-if” vs. “what-to”), the scenario settings and the possible analytical tools and indicators for the numerical analysis. Uncertainty quantification tools are then key elements of the assessment framework. We discuss the relevance of and challenges for the development of SA, with a specific focus on applicability in specific decision contexts, highlighted.JRC.H.8-Sustainability Assessmen

A contingency view to novelty: The role of product-service strategy, sensing capability and environmental turbulence

Purpose: The aim of this study is to examine (i) the impact of the fit between product-service strategy and sensing capability on novelty, and (ii) the potential moderating impact of contextual factors (i.e. technological and market turbulence) on novelty. Design/methodology/approach: In line with the aim of the study, a quantitative approach was adopted and a multi-item scale survey was designed to collect primary data. Using a mixed mode survey, a total number of 491 questionnaires were collected from a sample of UK-based telecommunications firms. Multiple regression was employed to test the hypotheses and predict the outcomes. Findings: The results support the positive contribution of a contingency approach to the study of the impact of the fit between product-service strategy and sensing dynamic capability on novelty. The results also partially confirm the reinforcing impact of technological and market turbulence on novelty. Originality/value: The current study extends research on product-service strategy and sensing capability by adopting a contingency view which intends to serve two purposes: (i)to complement the existing reductionistic explanations, and (ii) to explore how the relationship between product-service strategy and sensing capability could create novelty as well as the degree to which this relationship could be moderated in light of the external contextual factors

Assessment of fundamental strategic issues in structural change in United Kingdom and South African ports by systemic scenarios

The future complexity of strategic issues in international structural change was demonstrated by UK and SA ports. This arose from the likely extent of structural constraints and the effects of stakeholder power. From a review of emerging Advanced Systems Theory a new Boundary -spanning perspective of strategy was developed, that led to the specification of conceptual circumstances of potential outcomes of change. Since existing systems methodologies could not accommodate future power relationships, a new methodology and data collection technique was developed. The circumstances were developed into multiple scenarios which were judged by international decision-makers. These judgements were subjected to quantitative and qualitative analysis from a Strategic Choice Perspective. The outcome was a Boundary -spanning 'Long-term Strategic Service Industry' model which proposed the outlines of the future strategy and organisational structure that ought to be adopted to meet 'public interest' constraints. A dual subject and methodological contribution was made

Elucidating the Relationship between Chinese Medicine and Systems Biology: A Multi-Sited Ethnography

Ever since Chinese medicine encountered modern science in the late nineteenth century, the relationship between the two traditions has been extremely one-sided. At best, scientists perceived Chinese medicine as an archive of primitive knowledge from which potentially useful drugs could be extracted. Chinese medicine practitioners themselves, meanwhile, began a long struggle throughout the twentieth century to modernise their medicine with the help of Western theories and technology. At the turn of the twenty-first century, the involvement of systems biologists in Chinese medicine research created a new encounter, however, that, at least in the rhetoric of its actors, promised a very different kind of relationship: a match of two systems brought together by a shared interest in understanding life, health, illness and medicine as intrinsically complex and not amenable to the reductionist approaches of mainstream science. This research empirically investigates the nature of this relationship and how it emerged. It aims to contribute to the contemporary history of Chinese medicine by exploring the relationship between Chinese medicine and systems biology. This thesis argues that a heterogeneous network evolved, which is composed of human and nonhuman actors and their interactions created globally distributed research projects on Chinese medicine and systems biology. For the purpose of this research, a multi-sited ethnography was conducted over a period of eleven months and a literature survey was employed to trace the start and the development of this heterogeneous network. Ethnographic data reveals in four chapters on the rhetoric and perceptions of the actors, their involvement in Chinese medicine research, their laboratory practice, and the networks and political ties, which developed into a heterogeneous network of Chinese medicine and systems biology research. This research concludes that in the 2000s, a heterogeneous network emerged through the shared ideologies of systems thinking and holism. The shared ideologies set the groundwork for systems biologists to engage with Chinese medicine on its own terms, and created scientific practices, co-operation and funding opportunities between Europe and China

Design Ltd.: Renovated Myths for the Development of Socially Embedded Technologies

This paper argues that traditional and mainstream mythologies, which have been continually told within the Information Technology domain among designers and advocators of conceptual modelling since the 1960s in different fields of computing sciences, could now be renovated or substituted in the mould of more recent discourses about performativity, complexity and end-user creativity that have been constructed across different fields in the meanwhile. In the paper, it is submitted that these discourses could motivate IT professionals in undertaking alternative approaches toward the co-construction of socio-technical systems, i.e., social settings where humans cooperate to reach common goals by means of mediating computational tools. The authors advocate further discussion about and consolidation of some concepts in design research, design practice and more generally Information Technology (IT) development, like those of: task-artifact entanglement, universatility (sic) of End-User Development (EUD) environments, bricolant/bricoleur end-user, logic of bricolage, maieuta-designers (sic), and laissez-faire method to socio-technical construction. Points backing these and similar concepts are made to promote further discussion on the need to rethink the main assumptions underlying IT design and development some fifty years later the coming of age of software and modern IT in the organizational domain.Comment: This is the peer-unreviewed of a manuscript that is to appear in D. Randall, K. Schmidt, & V. Wulf (Eds.), Designing Socially Embedded Technologies: A European Challenge (2013, forthcoming) with the title "Building Socially Embedded Technologies: Implications on Design" within an EUSSET editorial initiative (www.eusset.eu/

CoCoNet: towards coast to coast networks of marine protected areas (from the shore to the high and deep sea), coupled with sea-based wind energy potential

This volume contains the main results of the EC FP7 “The Ocean of Tomorrow” Project CoCoNet, divided in two sections: 1) a set of guidelines to design networks of Marine Protected Areas in the Mediterranean and the Black Seas; 2) a smart wind chart that will allow evaluating the possibility of installing Offshore Wind Farms in both seas. The concept of Cells of Ecosystem Functioning, based on connectivity, is introduced to define natural units of management and conservation. The definition of Good Environmental Status, as defined in the Marine Strategy Framework Directive, is fully embraced to set the objectives of the project, by adopting a holistic approach that integrates a full set of disciplines, ranging from physics to bio-ecology, economics, engineering and many sub-disciplines. The CoCoNet Consortium involved scientist sfrom 22 states, based in Africa, Asia, and Europe, contributing to build a coherent scientific community.peer-reviewe

CoCoNet: towards coast to coast networks of Marine Protected Areas (from the shore to the high and deep sea), coupled with sea-based wind energy potential.

Abstract This volume contains the main results of the EC FP7 “The Ocean of Tomorrow” Project CoCoNet, divided in two sections: 1) a set of guidelines to design networks of Marine Protected Areas in the Mediterranean and the Black Seas; 2) a smart wind chart that will allow evaluating the possibility of installing Offshore Wind Farms in both seas. The concept of Cells of Ecosystem Functioning, based on connectivity, is introduced to define natural units of management and conservation. The definition of Good Environmental Status, as defined in the Marine Strategy Framework Directive, is fully embraced to set the objectives of the project, by adopting a holistic approach that integrates a full set of disciplines, ranging from physics to bio-ecology, economics, engineering and many sub-disciplines. The CoCoNet Consortium involved scientist sfrom 22 states, based in Africa, Asia, and Europe, contributing to build a coherent scientific community

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic.

Biomarker discovery and development for clinical research, diagnostics and therapy monitoring in clinical trials have advanced rapidly in key areas of medicine - most notably, oncology and cardiovascular diseases - allowing rapid early detection and supporting the evolution of biomarker-guided, precision-medicine-based targeted therapies. In Alzheimer disease (AD), breakthroughs in biomarker identification and validation include cerebrospinal fluid and PET markers of amyloid-β and tau proteins, which are highly accurate in detecting the presence of AD-associated pathophysiological and neuropathological changes. However, the high cost, insufficient accessibility and/or invasiveness of these assays limit their use as viable first-line tools for detecting patterns of pathophysiology. Therefore, a multistage, tiered approach is needed, prioritizing development of an initial screen to exclude from these tests the high numbers of people with cognitive deficits who do not demonstrate evidence of underlying AD pathophysiology. This Review summarizes the efforts of an international working group that aimed to survey the current landscape of blood-based AD biomarkers and outlines operational steps for an effective academic-industry co-development pathway from identification and assay development to validation for clinical use.I recieved an honorarium from Roche Diagnostics for my participation in the advisory panel meeting leading to this pape