8,708 research outputs found
Logical openness in Cognitive Models
It is here proposed an analysis of symbolic and sub-symbolic models for studying cognitive processes, centered on emergence and logical openness notions. The Theory of logical openness connects the Physics of system/environment relationships to the system informational structure. In this theory, cognitive models can be ordered according to a hierarchy of complexity depending on their logical openness degree, and their descriptive limits are correlated to Gödel-Turing Theorems on formal systems. The symbolic models with low logical openness describe cognition by means of semantics which fix the system/environment relationship (cognition in vitro), while the sub-symbolic ones with high logical openness tends to seize its evolutive dynamics (cognition in vivo). An observer is defined as a system with high logical openness. In conclusion, the characteristic processes of intrinsic emergence typical of “bio-logic” - emerging of new codes-require an alternative model to Turing-computation, the natural or bio-morphic computation, whose essential features we are going here to outline
Genetic programming in data mining for drug discovery
Genetic programming (GP) is used to extract from rat oral bioavailability
(OB) measurements simple, interpretable and predictive QSAR models
which both generalise to rats and to marketed drugs in humans. Receiver
Operating Characteristics (ROC) curves for the binary classier produced
by machine learning show no statistical dierence between rats (albeit
without known clearance dierences) and man. Thus evolutionary computing
oers the prospect of in silico ADME screening, e.g. for \virtual"
chemicals, for pharmaceutical drug discovery
Non-systemic transmission of tick-borne diseases: a network approach
Tick-Borne diseases can be transmitted via non-systemic (NS) transmission.
This occurs when tick gets the infection by co-feeding with infected ticks on
the same host resulting in a direct pathogen transmission between the vectors,
without infecting the host. This transmission is peculiar, as it does not
require any systemic infection of the host. The NS transmission is the main
efficient transmission for the persistence of the Tick-Borne Encephalitis virus
in nature. By describing the heterogeneous ticks aggregation on hosts through a
\hyphenation{dynamical} bipartite graphs representation, we are able to
mathematically define the NS transmission and to depict the epidemiological
conditions for the pathogen persistence. Despite the fact that the underlying
network is largely fragmented, analytical and computational results show that
the larger is the variability of the aggregation, and the easier is for the
pathogen to persist in the population.Comment: 15 pages, 4 figures, to be published in Communications in Nonlinear
Science and Numerical Simulatio
Actuating (Auto)Poiesis
This paper claims that the use of the computer as generative methodological tool for designing urban and building scenarios (when perceived systematically) is a misnomer, because the typical approach does not account for the incompleteness of computational processes. We will argue that the computerisation of architectural and urban scenarios with autopoietic and/or artificial life simulations does not account for what Edsger W. Dijkstra called “radical novelty”; and Gilles Deleuze termed “line of flight”. Typical computational methods do not open up genuine alternatives that produce radical morphologies. Our argument is predicated on the dominant notion of computation as opposed to a critique of computation per se. A critical analysis of the perception of novelty is made to support our view, and its connection with the incompleteness of axiomatic systems is explored in relation to three phases of cybernetic enquiry. Our argument draws on the ontologies of Alfred North Whitehead and Gilles Deleuze, which we utilise to reorient computational design to emphasise the potential of generating radical novelty and identify the inherent locus therein a matter of nonhuman decision-making
Architecture of Environmental Risk Modelling: for a faster and more robust response to natural disasters
Demands on the disaster response capacity of the European Union are likely to
increase, as the impacts of disasters continue to grow both in size and
frequency. This has resulted in intensive research on issues concerning
spatially-explicit information and modelling and their multiple sources of
uncertainty. Geospatial support is one of the forms of assistance frequently
required by emergency response centres along with hazard forecast and event
management assessment. Robust modelling of natural hazards requires dynamic
simulations under an array of multiple inputs from different sources.
Uncertainty is associated with meteorological forecast and calibration of the
model parameters. Software uncertainty also derives from the data
transformation models (D-TM) needed for predicting hazard behaviour and its
consequences. On the other hand, social contributions have recently been
recognized as valuable in raw-data collection and mapping efforts traditionally
dominated by professional organizations. Here an architecture overview is
proposed for adaptive and robust modelling of natural hazards, following the
Semantic Array Programming paradigm to also include the distributed array of
social contributors called Citizen Sensor in a semantically-enhanced strategy
for D-TM modelling. The modelling architecture proposes a multicriteria
approach for assessing the array of potential impacts with qualitative rapid
assessment methods based on a Partial Open Loop Feedback Control (POLFC) schema
and complementing more traditional and accurate a-posteriori assessment. We
discuss the computational aspect of environmental risk modelling using
array-based parallel paradigms on High Performance Computing (HPC) platforms,
in order for the implications of urgency to be introduced into the systems
(Urgent-HPC).Comment: 12 pages, 1 figure, 1 text box, presented at the 3rd Conference of
Computational Interdisciplinary Sciences (CCIS 2014), Asuncion, Paragua
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