36,408 research outputs found
PocketCare: Tracking the Flu with Mobile Phones using Partial Observations of Proximity and Symptoms
Mobile phones provide a powerful sensing platform that researchers may adopt
to understand proximity interactions among people and the diffusion, through
these interactions, of diseases, behaviors, and opinions. However, it remains a
challenge to track the proximity-based interactions of a whole community and
then model the social diffusion of diseases and behaviors starting from the
observations of a small fraction of the volunteer population. In this paper, we
propose a novel approach that tries to connect together these sparse
observations using a model of how individuals interact with each other and how
social interactions happen in terms of a sequence of proximity interactions. We
apply our approach to track the spreading of flu in the spatial-proximity
network of a 3000-people university campus by mobilizing 300 volunteers from
this population to monitor nearby mobile phones through Bluetooth scanning and
to daily report flu symptoms about and around them. Our aim is to predict the
likelihood for an individual to get flu based on how often her/his daily
routine intersects with those of the volunteers. Thus, we use the daily
routines of the volunteers to build a model of the volunteers as well as of the
non-volunteers. Our results show that we can predict flu infection two weeks
ahead of time with an average precision from 0.24 to 0.35 depending on the
amount of information. This precision is six to nine times higher than with a
random guess model. At the population level, we can predict infectious
population in a two-week window with an r-squared value of 0.95 (a random-guess
model obtains an r-squared value of 0.2). These results point to an innovative
approach for tracking individuals who have interacted with people showing
symptoms, allowing us to warn those in danger of infection and to inform health
researchers about the progression of contact-induced diseases
Modeling Infection with Multi-agent Dynamics
Developing the ability to comprehensively study infections in small
populations enables us to improve epidemic models and better advise individuals
about potential risks to their health. We currently have a limited
understanding of how infections spread within a small population because it has
been difficult to closely track an infection within a complete community. The
paper presents data closely tracking the spread of an infection centered on a
student dormitory, collected by leveraging the residents' use of cellular
phones. The data are based on daily symptom surveys taken over a period of four
months and proximity tracking through cellular phones. We demonstrate that
using a Bayesian, discrete-time multi-agent model of infection to model
real-world symptom reports and proximity tracking records gives us important
insights about infec-tions in small populations
Epidemic processes in complex networks
In recent years the research community has accumulated overwhelming evidence
for the emergence of complex and heterogeneous connectivity patterns in a wide
range of biological and sociotechnical systems. The complex properties of
real-world networks have a profound impact on the behavior of equilibrium and
nonequilibrium phenomena occurring in various systems, and the study of
epidemic spreading is central to our understanding of the unfolding of
dynamical processes in complex networks. The theoretical analysis of epidemic
spreading in heterogeneous networks requires the development of novel
analytical frameworks, and it has produced results of conceptual and practical
relevance. A coherent and comprehensive review of the vast research activity
concerning epidemic processes is presented, detailing the successful
theoretical approaches as well as making their limits and assumptions clear.
Physicists, mathematicians, epidemiologists, computer, and social scientists
share a common interest in studying epidemic spreading and rely on similar
models for the description of the diffusion of pathogens, knowledge, and
innovation. For this reason, while focusing on the main results and the
paradigmatic models in infectious disease modeling, the major results
concerning generalized social contagion processes are also presented. Finally,
the research activity at the forefront in the study of epidemic spreading in
coevolving, coupled, and time-varying networks is reported.Comment: 62 pages, 15 figures, final versio
- …