16,105 research outputs found
Using Neural Networks for Relation Extraction from Biomedical Literature
Using different sources of information to support automated extracting of
relations between biomedical concepts contributes to the development of our
understanding of biological systems. The primary comprehensive source of these
relations is biomedical literature. Several relation extraction approaches have
been proposed to identify relations between concepts in biomedical literature,
namely, using neural networks algorithms. The use of multichannel architectures
composed of multiple data representations, as in deep neural networks, is
leading to state-of-the-art results. The right combination of data
representations can eventually lead us to even higher evaluation scores in
relation extraction tasks. Thus, biomedical ontologies play a fundamental role
by providing semantic and ancestry information about an entity. The
incorporation of biomedical ontologies has already been proved to enhance
previous state-of-the-art results.Comment: Artificial Neural Networks book (Springer) - Chapter 1
What's unusual in online disease outbreak news?
Background: Accurate and timely detection of public health events of
international concern is necessary to help support risk assessment and response
and save lives. Novel event-based methods that use the World Wide Web as a
signal source offer potential to extend health surveillance into areas where
traditional indicator networks are lacking. In this paper we address the issue
of systematically evaluating online health news to support automatic alerting
using daily disease-country counts text mined from real world data using
BioCaster. For 18 data sets produced by BioCaster, we compare 5 aberration
detection algorithms (EARS C2, C3, W2, F-statistic and EWMA) for performance
against expert moderated ProMED-mail postings. Results: We report sensitivity,
specificity, positive predictive value (PPV), negative predictive value (NPV),
mean alerts/100 days and F1, at 95% confidence interval (CI) for 287
ProMED-mail postings on 18 outbreaks across 14 countries over a 366 day period.
Results indicate that W2 had the best F1 with a slight benefit for day of week
effect over C2. In drill down analysis we indicate issues arising from the
granular choice of country-level modeling, sudden drops in reporting due to day
of week effects and reporting bias. Automatic alerting has been implemented in
BioCaster available from http://born.nii.ac.jp. Conclusions: Online health news
alerts have the potential to enhance manual analytical methods by increasing
throughput, timeliness and detection rates. Systematic evaluation of health
news aberrations is necessary to push forward our understanding of the complex
relationship between news report volumes and case numbers and to select the
best performing features and algorithms
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