Paper Session III-B - A Roadmap for Space Microelectronics Technology into the New Millennium

Advances in microelectronics technologies over the past several decades have truly revolutionized modern society in almost every aspect of human endeavor. The continuous scaling of the commercial semiconductor technology to smaller and smaller device and interconnect feature sizes (referred to as Mooreís Law due to Gordon Moore of Intel) has lead to more and more functionality being developed onto a single silicon ëchipí. Moreover, the manufacturing cost of an on-chip function is getting cheaper and cheaper. These two factors: ëmore for lessí represents the fuel that has propelled the microelectronics technology revolution of the 20th century. How long will this technology revolution last into the new millennium is a key question that the semiconductor industry is continuously evaluating. An excellent roadmap of the commercial semiconductor technology needs for the next 15 years (from 1997 to 2012) is described in The National Technology Roadmap for Semiconductors, published by the Semiconductor Industry Association (SIA) in December 1997 [1]

Doctor of Philosophy

dissertationSince the late 1950s, scientists have been working toward realizing implantable devices that would directly monitor or even control the human body's internal activities. Sophisticated microsystems are used to improve our understanding of internal biological processes in animals and humans. The diversity of biomedical research dictates that microsystems must be developed and customized specifically for each new application. For advanced long-term experiments, a custom designed system-on-chip (SoC) is usually necessary to meet desired specifications. Custom SoCs, however, are often prohibitively expensive, preventing many new ideas from being explored. In this work, we have identified a set of sensors that are frequently used in biomedical research and developed a single-chip integrated microsystem that offers the most commonly used sensor interfaces, high computational power, and which requires minimum external components to operate. Included peripherals can also drive chemical reactions by setting the appropriate voltages or currents across electrodes. The SoC is highly modular and well suited for prototyping in and ex vivo experimental devices. The system runs from a primary or secondary battery that can be recharged via two inductively coupled coils. The SoC includes a 16-bit microprocessor with 32 kB of on chip SRAM. The digital core consumes 350 μW at 10 MHz and is capable of running at frequencies up to 200 MHz. The integrated microsystem has been fabricated in a 65 nm CMOS technology and the silicon has been fully tested. Integrated peripherals include two sigma-delta analog-to-digital converters, two 10-bit digital-to-analog converters, and a sleep mode timer. The system also includes a wireless ultra-wideband (UWB) transmitter. The fullydigital transmitter implementation occupies 68 x 68 μm2 of silicon area, consumes 0.72 μW static power, and achieves an energy efficiency of 19 pJ/pulse at 200 MHz pulse repetition frequency. An investigation of the suitability of the UWB technology for neural recording systems is also presented. Experimental data capturing the UWB signal transmission through an animal head are presented and a statistical model for large-scale signal fading is developed

Healthy aims: developing new medical implants and diagnostic equipment

Healthy Aims is a €23-million, four-year project, funded under the EU’s Information Society Technology Sixth Framework program to develop intelligent medical implants and diagnostic systems (www.healthyaims.org). The project has 25 partners from 10 countries, including commercial, clinical, and research groups. This consortium represents a combination of disciplines to design and fabricate new medical devices and components as well as to test them in laboratories and subsequent clinical trials. The project focuses on medical implants for nerve stimulation and diagnostic equipment based on straingauge technology

A programmable microsystem using system-on-chip for real-time biotelemetry

A telemetry microsystem, including multiple sensors, integrated instrumentation and a wireless interface has been implemented. We have employed a methodology akin to that for System-on-Chip microelectronics to design an integrated circuit instrument containing several "intellectual property" blocks that will enable convenient reuse of modules in future projects. The present system was optimized for low-power and included mixed-signal sensor circuits, a programmable digital system, a feedback clock control loop and RF circuits integrated on a 5 mm × 5 mm silicon chip using a 0.6 μm, 3.3 V CMOS process. Undesirable signal coupling between circuit components has been investigated and current injection into sensitive instrumentation nodes was minimized by careful floor-planning. The chip, the sensors, a magnetic induction-based transmitter and two silver oxide cells were packaged into a 36 mm × 12 mm capsule format. A base station was built in order to retrieve the data from the microsystem in real-time. The base station was designed to be adaptive and timing tolerant since the microsystem design was simplified to reduce power consumption and size. The telemetry system was found to have a packet error rate of 10<sup>-</sup><sup>3</sup> using an asynchronous simplex link. Trials in animal carcasses were carried out to show that the transmitter was as effective as a conventional RF device whilst consuming less power

CUSTARD (Cranfield University Space Technology Advanced Research Demonstrator) - A Micro-System Technology Demonstrator Nanosatellite. Summary of the Group Design Project MSc in Astronautics and Space Engineering. 1999-2000, Cranfield University

CUSTARD (Cranfield University Space Technology And Research Demonstrator) was the group design project for students of the MSc in Astronautics and Space Engineering for the Academic Year 1999/2000 at Cranfield University. The project involved the initial design of a nanosatellite to be used as a technology demonstrator for microsystem technology (MST) in space. The students worked together as one group (organised into several subgroups, e.g. system, mechanical), with each student responsible for a set of work packages. The nanosatellite designed had a mass of 4 kg, lifetime of 3 months in low Earth orbit, coarse 3-axis attitude control (no orbit control), and was capable of carrying up to 1 kg of payload. The electrical power available was 18 W (peak). Assuming a single X-band ground station at RAL (UK), a data rate of up to 1 M bit s-1 for about 3000 s per day is possible. The payloads proposed are a microgravity laboratory and a formation flying experiment. The report summarises the results of the project and includes executive summaries from all team members. Further information and summaries of the full reports are available from the College of Aeronautics, Cranfield University

Optical microsensor for counting food substance particles in lab-on-a-chips

Integrated optical detection is considered to be an important operation in lab-on-a-chips. This paper presents an optical fiber-based micro-sensor that is capable of detecting food substance particles in a lab-on-a-chip. The system consists of a microcontroller and associated circuitry, a laser emitter, a laser receiver, fiber optic cables, a microfluidics chip, and the food substance samples to be tested. When the particles flow through the microfluidic channel in the chip, the receiver’s output voltage varies due to the particles blocking the passage of the laser ray. The changes in the collected signals are analyzed to count the number of particles. Experiments are conducted on several food substance samples including talcum powder, ground ginger, and soy sauce. The experimental results are presented and discussed

Absorbance based light emitting diode optical sensors and sensing devices

The ever increasing demand for in situ monitoring of health, environment and security has created a need for reliable, miniaturised sensing devices. To achieve this, appropriate analytical devices are required that possess operating characteristics of reliability, low power consumption, low cost, autonomous operation capability and compatibility with wireless communications systems. The use of light emitting diodes (LEDs) as light sources is one strategy, which has been successfully applied in chemical sensing. This paper summarises the development and advancement of LED based chemical sensors and sensing devices in terms of their configuration and application, with the focus on transmittance and reflectance absorptiometric measurements

Nanosciences : evolution or revolution ?

12 pagesIn miniaturised objects fabricated by modern technology the smallest linear size may be of a few nanometers. In the field of microelectronics, the advantages of such a miniaturisation are huge (increased complexity and reliability, reduced costs). The technology is now approaching the limits where further size reduction will be impossible, except for very novel techniques such as molecular electronics. Miniaturization research has also led to the discovery of nanometric objects such as carbon nanotubes, which turn out to be particularly appropriate for inventing new materials. Miniaturization techniques have been progressively applied in other fields, with the hope of obtaining improvements similar to those encountered in microelectronics. Examples are bio chips, which concentrate on a few cm2 the recognition of ADN sequences, or 'lab-on-a-chip' devices, each of which constitutes a whole laboratory of chemical analysis, or MEMs (Micro ElectroMechanical Systems). New therapies will use miniaturized objects with multiple functions: For instance a nanoparticle can both recognize the target organ thanks to an appropriate protein, and deliver the therapeutic molecule to this target. These results have only been possible through new observation instruments, able to observe and manipulate nano objects. Is the observed evolution really a revolution of science and techniques? This is a point discussed in the conclusion, which also deals with risks associated to nanotechnologies, while the need for a social regulation is stressed

Differences in intestinal size, structure, and function contributing to feed efficiency in broiler chickens reared at geographically distant locations

The contribution of the intestinal tract to differences in residual feed intake (RFI) has been inconclusively studied in chickens so far. It is also not clear if RFI-related differences in intestinal function are similar in chickens raised in different environments. The objective was to investigate differences in nutrient retention, visceral organ size, intestinal morphology, jejunal permeability and expression of genes related to barrier function, and innate immune response in chickens of diverging RFI raised at 2 locations (L1: Austria; L2: UK). The experimental protocol was similar, and the same dietary formulation was fed at the 2 locations. Individual BW and feed intake (FI) of chickens (Cobb 500FF) were recorded from d 7 of life. At 5 wk of life, chickens (L1, n = 157; L2 = 192) were ranked according to their RFI, and low, medium, and high RFI chickens were selected (n = 9/RFI group, sex, and location). RFI values were similar between locations within the same RFI group and increased by 446 and 464 g from low to high RFI in females and males, respectively. Location, but not RFI rank, affected growth, nutrient retention, size of the intestine, and jejunal disaccharidase activity. Chickens from L2 had lower total body weight gain and mucosal enzyme activity but higher nutrient retention and longer intestines than chickens at L1. Parameters determined only at L1 showed increased crypt depth in the duodenum and jejunum and enhanced paracellular permeability in low vs. high RFI females. Jejunal expression of IL1B was lower in low vs. high RFI females at L2, whereas that of TLR4 at L1 and MCT1 at both locations was higher in low vs. high RFI males. Correlation analysis between intestinal parameters and feed efficiency metrics indicated that feed conversion ratio was more correlated to intestinal size and function than was RFI. In conclusion, the rearing environment greatly affected intestinal size and function, thereby contributing to the variation in chicken RFI observed across locations