51,692 research outputs found

    Comparison of next-generation portable pollution monitors to measure exposure to PM2.5 from household air pollution in Puno, Peru.

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    Assessment of personal exposure to PM2.5 is critical for understanding intervention effectiveness and exposure-response relationships in household air pollution studies. In this pilot study, we compared PM2.5 concentrations obtained from two next-generation personal exposure monitors (the Enhanced Children MicroPEM or ECM; and the Ultrasonic Personal Air Sampler or UPAS) to those obtained with a traditional Triplex Cyclone and SKC Air Pump (a gravimetric cyclone/pump sampler). We co-located cyclone/pumps with an ECM and UPAS to obtain 24-hour kitchen concentrations and personal exposure measurements. We measured Spearmen correlations and evaluated agreement using the Bland-Altman method. We obtained 215 filters from 72 ECM and 71 UPAS co-locations. Overall, the ECM and the UPAS had similar correlation (ECM ρ = 0.91 vs UPAS ρ = 0.88) and agreement (ECM mean difference of 121.7 µg/m3 vs UPAS mean difference of 93.9 µg/m3 ) with overlapping confidence intervals when compared against the cyclone/pump. When adjusted for the limit of detection, agreement between the devices and the cyclone/pump was also similar for all samples (ECM mean difference of 68.8 µg/m3 vs UPAS mean difference of 65.4 µg/m3 ) and personal exposure samples (ECM mean difference of -3.8 µg/m3 vs UPAS mean difference of -12.9 µg/m3 ). Both the ECM and UPAS produced comparable measurements when compared against a cyclone/pump setup

    RIDDLE: Race and ethnicity Imputation from Disease history with Deep LEarning

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    Anonymized electronic medical records are an increasingly popular source of research data. However, these datasets often lack race and ethnicity information. This creates problems for researchers modeling human disease, as race and ethnicity are powerful confounders for many health exposures and treatment outcomes; race and ethnicity are closely linked to population-specific genetic variation. We showed that deep neural networks generate more accurate estimates for missing racial and ethnic information than competing methods (e.g., logistic regression, random forest). RIDDLE yielded significantly better classification performance across all metrics that were considered: accuracy, cross-entropy loss (error), and area under the curve for receiver operating characteristic plots (all p<106p < 10^{-6}). We made specific efforts to interpret the trained neural network models to identify, quantify, and visualize medical features which are predictive of race and ethnicity. We used these characterizations of informative features to perform a systematic comparison of differential disease patterns by race and ethnicity. The fact that clinical histories are informative for imputing race and ethnicity could reflect (1) a skewed distribution of blue- and white-collar professions across racial and ethnic groups, (2) uneven accessibility and subjective importance of prophylactic health, (3) possible variation in lifestyle, such as dietary habits, and (4) differences in background genetic variation which predispose to diseases

    Utilizing rapid prototyping 3D printer for fabricating flexographic PDMS printing plate

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    Recently printed electronic field is significantly growth. Printed electronic is to develop electrical devices by printing method. Conventional printing method that has been studied for this kind of printed electronic such as flexographic, micro contact printing, screen printing, gravure and ink jet. In flexographic and microcontact printing, a printing plate is used to transfer the designed and desired pattern to substrate through conformed contact. Therefore printing plate is play a big role in this area. Printing plate making by photopolymer which used in flexographic have limitation in achieving a micro-scale of pattern size. However, printing plate of microcontact printing have an advantages in producing micro, even nano-scale size by PDMS (Polydimethylsiloxane). Hence, rapid prototyping 3D printer was used for developing a PDMS micro-scale printing plate which will be used in reel to reel (R2R) flexographic due to high speed, low cost, mass production of this type of printing process. The flexibility of 3D printer in producing any shape of pattern easily, contributed the success of this study. A nickel plating and glass etching master pattern was used in this study too as master pattern mould since 3D printer has been reached the micro size limitation. The finest multiple solid line array with 1mm width and 2mm gap pattern of printing plate was successfully fabricated by 3D printer master mould due to size limitation of the FDM (Fused Deposition Modeling) 3D printer nozzle itself. However, the micro-scale multiple solid line array of 100micron and 25micron successfully made by nikel platting and glass etching master mould respectively. Those types of printing plate producing method is valueable since it is easy, fast and low cost, used for micro-flexographic in printed electronic field or biomedical application

    Governance strategies in sustainable campus using Rasch model

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    In moving towards sustainability, university needs to establish a good governance strategy which practices to transform a positive sustainable culture toward successful green campus. Howe ver, due to constraint of knowledge and commitment regarding sustainability integration has caused weakness in the implementation of green concept in majority of Malaysian universities. This paper is presents one of the five dimensions of a developed hypot hetical integrated sustainable campus model which is university governance. The university governance dimension consists of 5 constructs and 23 items which are strategies for the university to be complied. These strategies were uncovered using questionnair e survey with 35 selected experts who are currently active in sustainable campus activities and researches. Collected data from this survey was analysed using Rasch method in Winstep software to measure items reliability, separation index, items polarity, item fit and item person map. Results from the analysis indicated that 19 strategies were significant to be implemented. Thus, it provides good information for universities to adopt these sustainable campus strategies in making their campus as a role mode l for a sustainable and conducive living environment
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