80,850 research outputs found
Switcher-random-walks: a cognitive-inspired mechanism for network exploration
Semantic memory is the subsystem of human memory that stores knowledge of
concepts or meanings, as opposed to life specific experiences. The organization
of concepts within semantic memory can be understood as a semantic network,
where the concepts (nodes) are associated (linked) to others depending on
perceptions, similarities, etc. Lexical access is the complementary part of
this system and allows the retrieval of such organized knowledge. While
conceptual information is stored under certain underlying organization (and
thus gives rise to a specific topology), it is crucial to have an accurate
access to any of the information units, e.g. the concepts, for efficiently
retrieving semantic information for real-time needings. An example of an
information retrieval process occurs in verbal fluency tasks, and it is known
to involve two different mechanisms: -clustering-, or generating words within a
subcategory, and, when a subcategory is exhausted, -switching- to a new
subcategory. We extended this approach to random-walking on a network
(clustering) in combination to jumping (switching) to any node with certain
probability and derived its analytical expression based on Markov chains.
Results show that this dual mechanism contributes to optimize the exploration
of different network models in terms of the mean first passage time.
Additionally, this cognitive inspired dual mechanism opens a new framework to
better understand and evaluate exploration, propagation and transport phenomena
in other complex systems where switching-like phenomena are feasible.Comment: 9 pages, 3 figures. Accepted in "International Journal of
Bifurcations and Chaos": Special issue on "Modelling and Computation on
Complex Networks
Dynamic systems as tools for analysing human judgement
With the advent of computers in the experimental labs, dynamic systems have become a new tool for research on problem solving and decision making. A short review on this research is given and the main features of these systems (connectivity and dynamics) are illustrated. To allow systematic approaches to the influential variables in this area, two formal frameworks (linear structural equations and finite state automata) are presented. Besides the formal background, it is shown how the task demands of system identification and system control can be realized in these environments and how psychometrically acceptable dependent variables can be derived
Exploration of Finite 2D Square Grid by a Metamorphic Robotic System
We consider exploration of finite 2D square grid by a metamorphic robotic
system consisting of anonymous oblivious modules. The number of possible shapes
of a metamorphic robotic system grows as the number of modules increases. The
shape of the system serves as its memory and shows its functionality. We
consider the effect of global compass on the minimum number of modules
necessary to explore a finite 2D square grid. We show that if the modules agree
on the directions (north, south, east, and west), three modules are necessary
and sufficient for exploration from an arbitrary initial configuration,
otherwise five modules are necessary and sufficient for restricted initial
configurations
Compulsive Social Behavior Emerges after Selective Ablation of Striatal Cholinergic Interneurons
The mechanisms underlying social dysfunction in neuropsychiatric conditions like obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) remain uncertain. Dysfunctions in basal ganglia, including reduced number of striatal cholinergic interneurons (SCIN), have been involved in their pathophysiology. To explore the role of SCIN in relation to perseverative behaviors we characterized a new transgenic mouse model in which inducible ablation of SCIN is achieved with high efficiency in a cell-type and region specific manner. Mice were subjected to an extensive behavioral testing including assessment of social behaviors and corticostriatal functional connectivity was evaluated in vivo. Selective SCIN ablation leads to altered social interactions together with exacerbated spontaneously emitted repetitive behaviors. Lesioned mice showed normal motor coordination, balance, and general locomotion. Interestingly, only environmentally-driven, but not self-directed, repetitive behaviors are exacerbated in lesioned mice. Remarkably, in mice with SCIN ablation the normal pattern of social exploration is continuously replayed. The emerging pattern of social interactions is highly predictable and invariant across time. In vivo electrophysiological recordings indicate that SCIN ablation results in an increase of the functional connectivity between different cortical areas and the motor, but not associative, region of the striatum. Our results identify a role of SCIN in suppressing perseverative behaviors including social related ones. In sum, SCIN ablation in mice leads to exacerbated ritualistic-like behaviors that impact on social performance providing a link between SCIN dysfunction and social impairments present in psychiatric disorders.Fil: Martos Schott, Yanina Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; ArgentinaFil: Braz, Bárbara Yael. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; ArgentinaFil: Beccaria, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; ArgentinaFil: Murer, Mario Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; ArgentinaFil: Belforte, Juan Emilio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; Argentin
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