Fast Hardware Implementations of Static P Systems

In this article we present a simulator of non-deterministic static P systems using Field Programmable Gate Array (FPGA) technology. Its major feature is a high performance, achieving a constant processing time for each transition. Our approach is based on representing all possible applications as words of some regular context-free language. Then, using formal power series it is possible to obtain the number of possibilities and select one of them following a uniform distribution, in a fair and non-deterministic way. According to these ideas, we yield an implementation whose results show an important speed-up, with a strong independence from the size of the P system.Ministry of Science and Innovation of the Spanish Government under the project TEC2011-27936 (HIPERSYS)European Regional Development Fund (ERDF)Ministry of Education of Spain (FPU grant AP2009-3625)ANR project SynBioTI

Principles of Neuromorphic Photonics

In an age overrun with information, the ability to process reams of data has become crucial. The demand for data will continue to grow as smart gadgets multiply and become increasingly integrated into our daily lives. Next-generation industries in artificial intelligence services and high-performance computing are so far supported by microelectronic platforms. These data-intensive enterprises rely on continual improvements in hardware. Their prospects are running up against a stark reality: conventional one-size-fits-all solutions offered by digital electronics can no longer satisfy this need, as Moore's law (exponential hardware scaling), interconnection density, and the von Neumann architecture reach their limits. With its superior speed and reconfigurability, analog photonics can provide some relief to these problems; however, complex applications of analog photonics have remained largely unexplored due to the absence of a robust photonic integration industry. Recently, the landscape for commercially-manufacturable photonic chips has been changing rapidly and now promises to achieve economies of scale previously enjoyed solely by microelectronics. The scientific community has set out to build bridges between the domains of photonic device physics and neural networks, giving rise to the field of \emph{neuromorphic photonics}. This article reviews the recent progress in integrated neuromorphic photonics. We provide an overview of neuromorphic computing, discuss the associated technology (microelectronic and photonic) platforms and compare their metric performance. We discuss photonic neural network approaches and challenges for integrated neuromorphic photonic processors while providing an in-depth description of photonic neurons and a candidate interconnection architecture. We conclude with a future outlook of neuro-inspired photonic processing.Comment: 28 pages, 19 figure

Tackling Exascale Software Challenges in Molecular Dynamics Simulations with GROMACS

GROMACS is a widely used package for biomolecular simulation, and over the last two decades it has evolved from small-scale efficiency to advanced heterogeneous acceleration and multi-level parallelism targeting some of the largest supercomputers in the world. Here, we describe some of the ways we have been able to realize this through the use of parallelization on all levels, combined with a constant focus on absolute performance. Release 4.6 of GROMACS uses SIMD acceleration on a wide range of architectures, GPU offloading acceleration, and both OpenMP and MPI parallelism within and between nodes, respectively. The recent work on acceleration made it necessary to revisit the fundamental algorithms of molecular simulation, including the concept of neighborsearching, and we discuss the present and future challenges we see for exascale simulation - in particular a very fine-grained task parallelism. We also discuss the software management, code peer review and continuous integration testing required for a project of this complexity.Comment: EASC 2014 conference proceedin

An Improved GPU Simulator For Spiking Neural P Systems

Spiking Neural P (SNP) systems, variants of Psystems (under Membrane and Natural computing), are computing models that acquire abstraction and inspiration from the way neurons 'compute' or process information. Similar to other P system variants, SNP systems are Turing complete models that by nature compute non-deterministically and in a maximally parallel manner. P systems usually trade (often exponential) space for (polynomial to constant) time. Due to this nature, P system variants are currently limited to parallel simulations, and several variants have already been simulated in parallel devices. In this paper we present an improved SNP system simulator based on graphics processing units (GPUs). Among other reasons, current GPUs are architectured for massively parallel computations, thus making GPUs very suitable for SNP system simulation. The computing model, hardware/software considerations, and simulation algorithm are presented, as well as the comparisons of the CPU only and CPU-GPU based simulators.Ministerio de Ciencia e Innovación TIN2009–13192Junta de Andalucía P08-TIC-0420

The Nondeterministic Waiting Time Algorithm: A Review

We present briefly the Nondeterministic Waiting Time algorithm. Our technique for the simulation of biochemical reaction networks has the ability to mimic the Gillespie Algorithm for some networks and solutions to ordinary differential equations for other networks, depending on the rules of the system, the kinetic rates and numbers of molecules. We provide a full description of the algorithm as well as specifics on its implementation. Some results for two well-known models are reported. We have used the algorithm to explore Fas-mediated apoptosis models in cancerous and HIV-1 infected T cells

From conventional membrane electrodes to ion-sensitive field-effect transistors

The theory concerning conventional membrane electrodes is often used as a starting point for the theoretical description of the operation of an ion-sensitive field-effect transistor. Although this results in a useful description of the device, a better view of the principles, and consequently the possibilities, of the new ion-sensitive device may result if the analysis is carried out in more detail, especially with respect to measuring concepts. This is presented in the paper. A careful comparison between the operation of a conventional membrane electrode and the i.s.f.e.t. leads to a definite classification of different types of i.s.f.e.t.s. These types are illustrated with corresponding measurements. In addition, the most appropriate application for each type is mentioned

On-chip Few-shot Learning with Surrogate Gradient Descent on a Neuromorphic Processor

Recent work suggests that synaptic plasticity dynamics in biological models of neurons and neuromorphic hardware are compatible with gradient-based learning (Neftci et al., 2019). Gradient-based learning requires iterating several times over a dataset, which is both time-consuming and constrains the training samples to be independently and identically distributed. This is incompatible with learning systems that do not have boundaries between training and inference, such as in neuromorphic hardware. One approach to overcome these constraints is transfer learning, where a portion of the network is pre-trained and mapped into hardware and the remaining portion is trained online. Transfer learning has the advantage that pre-training can be accelerated offline if the task domain is known, and few samples of each class are sufficient for learning the target task at reasonable accuracies. Here, we demonstrate on-line surrogate gradient few-shot learning on Intel's Loihi neuromorphic research processor using features pre-trained with spike-based gradient backpropagation-through-time. Our experimental results show that the Loihi chip can learn gestures online using a small number of shots and achieve results that are comparable to the models simulated on a conventional processor