3D printed ventricular septal defect patch: a primer for the 2015 Radiological Society of North America (RSNA) hands-on course in 3D printing.

Hand-held three dimensional models of the human anatomy and pathology, tailored-made protheses, and custom-designed implants can be derived from imaging modalities, most commonly Computed Tomography (CT). However, standard DICOM format images cannot be 3D printed; instead, additional image post-processing is required to transform the anatomy of interest into Standard Tessellation Language (STL) format is needed. This conversion, and the subsequent 3D printing of the STL file, requires a series of steps. Initial post-processing involves the segmentation-demarcation of the desired for 3D printing parts and creating of an initial STL file. Then, Computer Aided Design (CAD) software is used, particularly for wrapping, smoothing and trimming. Devices and implants that can also be 3D printed, can be designed using this software environment. The purpose of this article is to provide a tutorial on 3D Printing with the test case of complex congenital heart disease (CHD). While the infant was born with double outlet right ventricle (DORV), this hands-on guide to be featured at the 2015 annual meeting of the Radiological Society of North America Hands-on Course in 3D Printing focused on the additional finding of a ventricular septal defect (VSD). The process of segmenting the heart chambers and the great vessels will be followed by optimization of the model using CAD software. A virtual patch that accurately matches the patient's VSD will be designed and both models will be prepared for 3D printing

Consensus image method for unknown noise removal

Noise removal has been, and it is nowadays, an important task in computer vision. Usually, it is a previous task preceding other tasks, as segmentation or reconstruction. However, for most existing denoising algorithms the noise model has to be known in advance. In this paper, we introduce a new approach based on consensus to deal with unknown noise models. To do this, different filtered images are obtained, then combined using multifuzzy sets and averaging aggregation functions. The final decision is made by using a penalty function to deliver the compromised image. Results show that this approach is consistent and provides a good compromise between filters.This work is supported by the European Commission under Contract No. 238819 (MIBISOC Marie Curie ITN). H. Bustince was supported by Project TIN 2010-15055 of the Spanish Ministry of Science

Optimization and enhancement of H&E stained microscopical images by applying bilinear interpolation method on lab color mode

Background: Hematoxylin & Eosin (H&E) is a widely employed technique in pathology and histology to distinguish nuclei and cytoplasm in tissues by staining them in different colors. This procedure helps to ease the diagnosis by enhancing contrast through digital microscopes. However, microscopic digital images obtained from this technique usually suffer from uneven lighting, i.e. poor Koehler illumination. Several off-the-shelf methods particularly established to correct this problem along with some popular general commercial tools have been examined to find out a robust solution. Methods: First, the characteristics of uneven lighting in pathological images obtained from the H&E technique are revealed, and then how the quality of these images can be improved by employing bilinear interpolation based approach applied on the channels of Lab color mode is explored without losing any essential detail, especially for the color information of nuclei (hematoxylin stained sections). Second, an approach to enhance the nuclei details that are a fundamental part of diagnosis and crucially needed by the pathologists who work with digital images is demonstrated. Results: Merits of the proposed methodology are substantiated on sample microscopic images. The results show that the proposed methodology not only remedies the deficiencies of H&E microscopical images, but also enhances delicate details. Conclusions: Non-uniform illumination problems in H&E microscopical images can be corrected without compromising crucial details that are essential for revealing the features of tissue samples

JPEG steganography: A performance evaluation of quantization tables

The two most important aspects of any image based steganographic system are the imperceptibility and the capacity of the stego image. This paper evaluates the performance and efficiency of using optimized quantization tables instead of default JPEG tables within JPEG steganography. We found that using optimized tables significantly improves the quality of stego-images. Moreover, we used this optimization strategy to generate a 16x16 quantization table to be used instead of that suggested. The quality of stego-images was greatly improved when these optimized tables were used. This led us to suggest a new hybrid steganographic method in order to increase the embedding capacity. This new method is based on both and Jpeg-Jsteg methods. In this method, for each 16x16 quantized DCT block, the least two significant bits (2-LSBs) of each middle frequency coefficient are modified to embed two secret bits. Additionally, the Jpeg-Jsteg embedding technique is used for the low frequency DCT coefficients without modifying the DC coefficient. Our experimental results show that the proposed approach can provide a higher information-hiding capacity than the other methods tested. Furthermore, the quality of the produced stego-images is better than that of other methods which use the default tables

Medical image enhancement using threshold decomposition driven adaptive morphological filter

One of the most common degradations in medical images is their poor contrast quality. This suggests the use of contrast enhancement methods as an attempt to modify the intensity distribution of the image. In this paper, a new edge detected morphological filter is proposed to sharpen digital medical images. This is done by detecting the positions of the edges and then applying a class of morphological filtering. Motivated by the success of threshold decomposition, gradientbased operators are used to detect the locations of the edges. A morphological filter is used to sharpen these detected edges. Experimental results demonstrate that the detected edge deblurring filter improved the visibility and perceptibility of various embedded structures in digital medical images. Moreover, the performance of the proposed filter is superior to that of other sharpener-type filters