A New Multimodal Medical Image Fusion based on Laplacian Autoencoder with Channel Attention

Medical image fusion combines the complementary information of multimodal medical images to assist medical professionals in the clinical diagnosis of patients' disorders and provide guidance during preoperative and intra-operative procedures. Deep learning (DL) models have achieved end-to-end image fusion with highly robust and accurate fusion performance. However, most DL-based fusion models perform down-sampling on the input images to minimize the number of learnable parameters and computations. During this process, salient features of the source images become irretrievable leading to the loss of crucial diagnostic edge details and contrast of various brain tissues. In this paper, we propose a new multimodal medical image fusion model is proposed that is based on integrated Laplacian-Gaussian concatenation with attention pooling (LGCA). We prove that our model preserves effectively complementary information and important tissue structures.Comment: 10 pages, 6 figures, % table

A Review of Landcover Classification with Very-High Resolution Remotely Sensed Optical Images—Analysis Unit, Model Scalability and Transferability

As an important application in remote sensing, landcover classification remains one of the most challenging tasks in very-high-resolution (VHR) image analysis. As the rapidly increasing number of Deep Learning (DL) based landcover methods and training strategies are claimed to be the state-of-the-art, the already fragmented technical landscape of landcover mapping methods has been further complicated. Although there exists a plethora of literature review work attempting to guide researchers in making an informed choice of landcover mapping methods, the articles either focus on the review of applications in a specific area or revolve around general deep learning models, which lack a systematic view of the ever advancing landcover mapping methods. In addition, issues related to training samples and model transferability have become more critical than ever in an era dominated by data-driven approaches, but these issues were addressed to a lesser extent in previous review articles regarding remote sensing classification. Therefore, in this paper, we present a systematic overview of existing methods by starting from learning methods and varying basic analysis units for landcover mapping tasks, to challenges and solutions on three aspects of scalability and transferability with a remote sensing classification focus including (1) sparsity and imbalance of data; (2) domain gaps across different geographical regions; and (3) multi-source and multi-view fusion. We discuss in detail each of these categorical methods and draw concluding remarks in these developments and recommend potential directions for the continued endeavor

An improved approach for medical image fusion using sparse representation and Siamese convolutional neural network

Multimodal image fusion is a contemporary branch of medical imaging that aims to increase the accuracy of clinical diagnosis of the disease stage development. The fusion of different image modalities can be a viable medical imaging approach. It combines the best features to produce a composite image with higher quality than its predecessors and can significantly improve medical diagnosis. Recently, sparse representation (SR) and Siamese Convolutional Neural Network (SCNN) methods have been introduced independently for image fusion. However, some of the results from these approaches have recorded defects, such as edge blur, less visibility, and blocking artifacts. To remedy these deficiencies, in this paper, a smart blending approach based on a combination of SR and SCNN is introduced for image fusion, which comprises three steps as follows. Firstly, entire source images are fed into the classical orthogonal matching pursuit (OMP), where the SR-fused image is obtained using the max-rule that aims to improve pixel localization. Secondly, a novel scheme of SCNN-based K-SVD dictionary learning is re-employed for each source image. The method has shown good non-linearity behavior, contributing to increasing the fused output's sparsity characteristics and demonstrating better extraction and transfer of image details to the output fused image. Lastly, the fusion rule step employs a linear combination between steps 1 and 2 to obtain the final fused image. The results depict that the proposed method is advantageous, compared to other previous methods, notably by suppressing the artifacts produced by the traditional SR and SCNN model

Segmentation and classification of lung nodules from Thoracic CT scans : methods based on dictionary learning and deep convolutional neural networks.

Lung cancer is a leading cause of cancer death in the world. Key to survival of patients is early diagnosis. Studies have demonstrated that screening high risk patients with Low-dose Computed Tomography (CT) is invaluable for reducing morbidity and mortality. Computer Aided Diagnosis (CADx) systems can assist radiologists and care providers in reading and analyzing lung CT images to segment, classify, and keep track of nodules for signs of cancer. In this thesis, we propose a CADx system for this purpose. To predict lung nodule malignancy, we propose a new deep learning framework that combines Convolutional Neural Networks (CNN) and Recurrent Neural Networks (RNN) to learn best in-plane and inter-slice visual features for diagnostic nodule classification. Since a nodule\u27s volumetric growth and shape variation over a period of time may reveal information regarding the malignancy of nodule, separately, a dictionary learning based approach is proposed to segment the nodule\u27s shape at two time points from two scans, one year apart. The output of a CNN classifier trained to learn visual appearance of malignant nodules is then combined with the derived measures of shape change and volumetric growth in assigning a probability of malignancy to the nodule. Due to the limited number of available CT scans of benign and malignant nodules in the image database from the National Lung Screening Trial (NLST), we chose to initially train a deep neural network on the larger LUNA16 Challenge database which was built for the purpose of eliminating false positives from detected nodules in thoracic CT scans. Discriminative features that were learned in this application were transferred to predict malignancy. The algorithm for segmenting nodule shapes in serial CT scans utilizes a sparse combination of training shapes (SCoTS). This algorithm captures a sparse representation of a shape in input data through a linear span of previously delineated shapes in a training repository. The model updates shape prior over level set iterations and captures variabilities in shapes by a sparse combination of the training data. The level set evolution is therefore driven by a data term as well as a term capturing valid prior shapes. During evolution, the shape prior influence is adjusted based on shape reconstruction, with the assigned weight determined from the degree of sparsity of the representation. The discriminative nature of sparse representation, affords us the opportunity to compare nodules\u27 variations in consecutive time points and to predict malignancy. Experimental validations of the proposed segmentation algorithm have been demonstrated on 542 3-D lung nodule data from the LIDC-IDRI database which includes radiologist delineated nodule boundaries. The effectiveness of the proposed deep learning and dictionary learning architectures for malignancy prediction have been demonstrated on CT data from 370 biopsied subjects collected from the NLST database. Each subject in this database had at least two serial CT scans at two separate time points one year apart. The proposed RNN CAD system achieved an ROC Area Under the Curve (AUC) of 0.87, when validated on CT data from nodules at second sequential time point and 0.83 based on dictionary learning method; however, when nodule shape change and appearance were combined, the classifier performance improved to AUC=0.89