29,335 research outputs found

    Posterior Bearing Overhang Following Medial and Lateral Mobile Bearing Unicompartmental Knee Replacements

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    This study explores the extent of bearing overhang following mobile bearing Oxford unicompartmental knee replacement (OUKR) (Oxford Phase 3, Zimmer Biomet). The Oxford components are designed to be fully congruent, however knee movements involve femoral rollback, which may result in bearing overhang at the posterior margin of the tibial implant, with potential implications for; pain, wear, and dislocation. Movement is known to be greater, and therefore posterior overhang more likely to occur, with; lateral compared to medial implants, anterior cruciate ligament deficiency, and at extremes of movement. 24 medial, and 20 domed lateral, OUKRs underwent sagittal plane knee fluoroscopy during step‐up and forward lunge exercises. The bearing position was inferred from the relative position of the femoral and tibial components. Based on the individual component sizes and geometry the extent the posterior part of the bearing which overhung the posterior part of the tibial component was calculated. There was no significant posterior overhang in knees with medial implants. Knees with lateral domed implants exhibited overhang at flexion angles beyond 60°, the magnitude of which increased with increasing flexion angle, reaching a maximum of 50% of the bearing length at 140° (range 0‐140°). This demonstrates a clear difference between the kinematics, and prevalence and extent of posterior bearing overhang between medial and lateral OUKRs

    Impact of solar shading geometry on building energy use in hot humid climates with special reference to Malaysia

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    External solar shading devices can substantially reduce the cooling load of buildings and large energy savings can be achieved. Hence, intercepting the radiant heat wave before penetrating to the internal environment through envelope openings is the main criterion in designing solar shading. In hot and humid climate, one draw back of using shading devices is the risk to reduce daylight level thus increases in use of artificial lighting. Therefore it is important to understand the magnitude of energy consumption for cooling and lighting when shading devices are adapted in order to analyze optimum shading as energy conservation option in high-rise office buildings. In other words, little is known about the relationship between energy use and external horizontal shading device geometry. In an attempt to elucidate these complex relationships, a simple experiment of an office room is carried out using dynamic computer simulation program eQUEST- 3 (DOE 2.2). The study indicated depth of the external horizontal overhang can be manipulated to obtain an optimum energy use in high-rise buildings. The results showed that correlation between overhang depth and energy is an important aspect compared to correlation between overhang depth with building cooling loads and daylight level, especially in tropical climate conditions

    Experimental study of the formation and collapse of an overhang in the lateral spread of smouldering peat fires

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    Smouldering combustion is the driving phenomenon of wildfires in peatlands, and is responsible for large amounts of carbon emissions and haze episodes world wide. Compared to flaming fires, smouldering is slow, low-temperature, flameless, and most persistent, yet it is poorly understood. Peat, as a typical organic soil, is a porous and charring natural fuel, thus prone to smouldering. The spread of smouldering peat fire is a multidimensional phenomenon, including two main components: in-depth vertical and surface lateral spread. In this study, we investigate the lateral spread of peat fire under various moisture and wind conditions. Visual and infrared cameras as well as a thermocouple array are used to measure the temperature profile and the spread rate. For the first time the overhang, where smouldering spreads fastest beneath the free surface, is observed in the laboratory, which helps understand the interaction between oxygen supply and heat losses. The periodic formation and collapse of overhangs is observed. The overhang thickness is found to increase with moisture and wind speed, while the spread rate decreases with moisture and increases with wind speed. A simple theoretical analysis is proposed and shows that the formation of overhang is caused by the spread rate difference between the top and lower peat layers as well as the competition between oxygen supply and heat losses

    Robustness and modularity properties of a non-covalent DNA catalytic reaction

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    The biophysics of nucleic acid hybridization and strand displacement have been used for the rational design of a number of nanoscale structures and functions. Recently, molecular amplification methods have been developed in the form of non-covalent DNA catalytic reactions, in which single-stranded DNA (ssDNA) molecules catalyze the release of ssDNA product molecules from multi-stranded complexes. Here, we characterize the robustness and specificity of one such strand displacement-based catalytic reaction. We show that the designed reaction is simultaneously sensitive to sequence mutations in the catalyst and robust to a variety of impurities and molecular noise. These properties facilitate the incorporation of strand displacement-based DNA components in synthetic chemical and biological reaction networks

    Effect of Mach number on the structure of turbulent spots

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    Direct numerical simulations have been performed to study the dynamics of isolated turbulent spots in compressible isothermal-wall boundary layers. Results of a bypass transition scenario at Mach 2, 4 and 6 are presented. At all Mach numbers the evolved spots have a leading-edge overhang, followed by a turbulent core and a calmed region at the rear interface. The spots have an upstream-pointing arrowhead shape when visualized by near-wall slices, but a downstream-pointing arrowhead in slices away front the wall. The lateral spreading of the spot decreases substantially with the Mach number, consistent with a growth mechanism based on the instability of lateral shear layers. Evidence for a supersonic (Mach) mode substructure is found in the Mach 6 case, where coherent spanwise structures are observed under the spot overhang region
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