30 research outputs found
Cross-Platform Text Mining and Natural Language Processing Interoperability - Proceedings of the LREC2016 conference
No abstract available
Cross-Platform Text Mining and Natural Language Processing Interoperability - Proceedings of the LREC2016 conference
No abstract available
Ten Ways of Leveraging Ontologies for Rapid Natural Language Processing Customization for Multiple Use Cases in Disjoint Domains
With the ever-growing adoption of AI technologies by large enterprises, purely data-driven approaches have dominated the field in the recent years. For a single use case, a development process looks simple: agreeing on an annotation schema, labeling the data, and training the models. As the number of use cases and their complexity increases, the development teams face issues with collective governance of the models, scalability and reusablity of data and models. These issues are widely addressed on the engineering side, but not so much on the knowledge side. Ontologies have been a well-researched approach for capturing knowledge and can be used to augment a data-driven methodology. In this paper, we discuss 10 ways of leveraging ontologies for Natural Language Processing (NLP) and its applications. We use ontologies for rapid customization of a NLP pipeline, ontologyrelated standards to power a rule engine and provide standard output format. We also discuss various use cases for medical, enterprise, financial, legal, and security domains, centered around three NLP-based applications: semantic search, question answering and natural language querying
Integrating Natural Language Processing (NLP) and Language Resources Using Linked Data
This thesis is a compendium of scientific works and engineering
specifications that have been contributed to a large community of
stakeholders to be copied, adapted, mixed, built upon and exploited in
any way possible to achieve a common goal: Integrating Natural Language
Processing (NLP) and Language Resources Using Linked Data
The explosion of information technology in the last two decades has led
to a substantial growth in quantity, diversity and complexity of
web-accessible linguistic data. These resources become even more useful
when linked with each other and the last few years have seen the
emergence of numerous approaches in various disciplines concerned with
linguistic resources and NLP tools. It is the challenge of our time to
store, interlink and exploit this wealth of data accumulated in more
than half a century of computational linguistics, of empirical,
corpus-based study of language, and of computational lexicography in all
its heterogeneity.
The vision of the Giant Global Graph (GGG) was conceived by Tim
Berners-Lee aiming at connecting all data on the Web and allowing to
discover new relations between this openly-accessible data. This vision
has been pursued by the Linked Open Data (LOD) community, where the
cloud of published datasets comprises 295 data repositories and more
than 30 billion RDF triples (as of September 2011).
RDF is based on globally unique and accessible URIs and it was
specifically designed to establish links between such URIs (or
resources). This is captured in the Linked Data paradigm that postulates
four rules: (1) Referred entities should be designated by URIs, (2)
these URIs should be resolvable over HTTP, (3) data should be
represented by means of standards such as RDF, (4) and a resource should
include links to other resources.
Although it is difficult to precisely identify the reasons for the
success of the LOD effort, advocates generally argue that open licenses
as well as open access are key enablers for the growth of such a network
as they provide a strong incentive for collaboration and contribution by
third parties. In his keynote at BNCOD 2011, Chris Bizer argued that
with RDF the overall data integration effort can be âsplit between data
publishers, third parties, and the data consumerâ, a claim that can be
substantiated by observing the evolution of many large data sets
constituting the LOD cloud.
As written in the acknowledgement section, parts of this thesis has
received numerous feedback from other scientists, practitioners and
industry in many different ways. The main contributions of this thesis
are summarized here:
Part I â Introduction and Background.
During his keynote at the Language Resource and Evaluation Conference in
2012, Sören Auer stressed the decentralized, collaborative, interlinked
and interoperable nature of the Web of Data. The keynote provides strong
evidence that Semantic Web technologies such as Linked Data are on its
way to become main stream for the representation of language resources.
The jointly written companion publication for the keynote was later
extended as a book chapter in The Peopleâs Web Meets NLP and serves as
the basis for âIntroductionâ and âBackgroundâ, outlining some stages of
the Linked Data publication and refinement chain. Both chapters stress
the importance of open licenses and open access as an enabler for
collaboration, the ability to interlink data on the Web as a key feature
of RDF as well as provide a discussion about scalability issues and
decentralization. Furthermore, we elaborate on how conceptual
interoperability can be achieved by (1) re-using vocabularies, (2) agile
ontology development, (3) meetings to refine and adapt ontologies and
(4) tool support to enrich ontologies and match schemata.
Part II - Language Resources as Linked Data.
âLinked Data in Linguisticsâ and âNLP & DBpedia, an Upward Knowledge
Acquisition Spiralâ summarize the results of the Linked Data in
Linguistics (LDL) Workshop in 2012 and the NLP & DBpedia Workshop in
2013 and give a preview of the MLOD special issue. In total, five
proceedings â three published at CEUR (OKCon 2011, WoLE 2012, NLP &
DBpedia 2013), one Springer book (Linked Data in Linguistics, LDL 2012)
and one journal special issue (Multilingual Linked Open Data, MLOD to
appear) â have been (co-)edited to create incentives for scientists to
convert and publish Linked Data and thus to contribute open and/or
linguistic data to the LOD cloud. Based on the disseminated call for
papers, 152 authors contributed one or more accepted submissions to our
venues and 120 reviewers were involved in peer-reviewing.
âDBpedia as a Multilingual Language Resourceâ and âLeveraging the
Crowdsourcing of Lexical Resources for Bootstrapping a Linguistic Linked
Data Cloudâ contain this thesisâ contribution to the DBpedia Project in
order to further increase the size and inter-linkage of the LOD Cloud
with lexical-semantic resources. Our contribution comprises extracted
data from Wiktionary (an online, collaborative dictionary similar to
Wikipedia) in more than four languages (now six) as well as
language-specific versions of DBpedia, including a quality assessment of
inter-language links between Wikipedia editions and internationalized
content negotiation rules for Linked Data. In particular the work
described in created the foundation for a DBpedia Internationalisation
Committee with members from over 15 different languages with the common
goal to push DBpedia as a free and open multilingual language resource.
Part III - The NLP Interchange Format (NIF).
âNIF 2.0 Core Specificationâ, âNIF 2.0 Resources and Architectureâ and
âEvaluation and Related Workâ constitute one of the main contribution of
this thesis. The NLP Interchange Format (NIF) is an RDF/OWL-based format
that aims to achieve interoperability between Natural Language
Processing (NLP) tools, language resources and annotations. The core
specification is included in and describes which URI schemes and RDF
vocabularies must be used for (parts of) natural language texts and
annotations in order to create an RDF/OWL-based interoperability layer
with NIF built upon Unicode Code Points in Normal Form C. In , classes
and properties of the NIF Core Ontology are described to formally define
the relations between text, substrings and their URI schemes. contains
the evaluation of NIF.
In a questionnaire, we asked questions to 13 developers using NIF. UIMA,
GATE and Stanbol are extensible NLP frameworks and NIF was not yet able
to provide off-the-shelf NLP domain ontologies for all possible domains,
but only for the plugins used in this study. After inspecting the
software, the developers agreed however that NIF is adequate enough to
provide a generic RDF output based on NIF using literal objects for
annotations. All developers were able to map the internal data structure
to NIF URIs to serialize RDF output (Adequacy). The development effort
in hours (ranging between 3 and 40 hours) as well as the number of code
lines (ranging between 110 and 445) suggest, that the implementation of
NIF wrappers is easy and fast for an average developer. Furthermore the
evaluation contains a comparison to other formats and an evaluation of
the available URI schemes for web annotation.
In order to collect input from the wide group of stakeholders, a total
of 16 presentations were given with extensive discussions and feedback,
which has lead to a constant improvement of NIF from 2010 until 2013.
After the release of NIF (Version 1.0) in November 2011, a total of 32
vocabulary employments and implementations for different NLP tools and
converters were reported (8 by the (co-)authors, including Wiki-link
corpus, 13 by people participating in our survey and 11 more, of
which we have heard). Several roll-out meetings and tutorials were held
(e.g. in Leipzig and Prague in 2013) and are planned (e.g. at LREC
2014).
Part IV - The NLP Interchange Format in Use.
âUse Cases and Applications for NIFâ and âPublication of Corpora using
NIFâ describe 8 concrete instances where NIF has been successfully used.
One major contribution in is the usage of NIF as the recommended RDF
mapping in the Internationalization Tag Set (ITS) 2.0 W3C standard
and the conversion algorithms from ITS to NIF and back. One outcome
of the discussions in the standardization meetings and telephone
conferences for ITS 2.0 resulted in the conclusion there was no
alternative RDF format or vocabulary other than NIF with the required
features to fulfill the working group charter. Five further uses of NIF
are described for the Ontology of Linguistic Annotations (OLiA), the
RDFaCE tool, the Tiger Corpus Navigator, the OntosFeeder and
visualisations of NIF using the RelFinder tool. These 8 instances
provide an implemented proof-of-concept of the features of NIF.
starts with describing the conversion and hosting of the huge Google
Wikilinks corpus with 40 million annotations for 3 million web sites.
The resulting RDF dump contains 477 million triples in a 5.6 GB
compressed dump file in turtle syntax. describes how NIF can be used to
publish extracted facts from news feeds in the RDFLiveNews tool as
Linked Data.
Part V - Conclusions.
provides lessons learned for NIF, conclusions and an outlook on future
work. Most of the contributions are already summarized above. One
particular aspect worth mentioning is the increasing number of
NIF-formated corpora for Named Entity Recognition (NER) that have come
into existence after the publication of the main NIF paper Integrating
NLP using Linked Data at ISWC 2013. These include the corpora converted
by Steinmetz, Knuth and Sack for the NLP & DBpedia workshop and an
OpenNLP-based CoNLL converter by BrĂŒmmer. Furthermore, we are aware of
three LREC 2014 submissions that leverage NIF: NIF4OGGD - NLP
Interchange Format for Open German Governmental Data, N^3 â A Collection
of Datasets for Named Entity Recognition and Disambiguation in the NLP
Interchange Format and Global Intelligent Content: Active Curation of
Language Resources using Linked Data as well as an early implementation
of a GATE-based NER/NEL evaluation framework by Dojchinovski and Kliegr.
Further funding for the maintenance, interlinking and publication of
Linguistic Linked Data as well as support and improvements of NIF is
available via the expiring LOD2 EU project, as well as the CSA EU
project called LIDER, which started in November 2013. Based on the
evidence of successful adoption presented in this thesis, we can expect
a decent to high chance of reaching critical mass of Linked Data
technology as well as the NIF standard in the field of Natural Language
Processing and Language Resources.:CONTENTS
i introduction and background 1
1 introduction 3
1.1 Natural Language Processing . . . . . . . . . . . . . . . 3
1.2 Open licenses, open access and collaboration . . . . . . 5
1.3 Linked Data in Linguistics . . . . . . . . . . . . . . . . . 6
1.4 NLP for and by the Semantic Web â the NLP Inter-
change Format (NIF) . . . . . . . . . . . . . . . . . . . . 8
1.5 Requirements for NLP Integration . . . . . . . . . . . . 10
1.6 Overview and Contributions . . . . . . . . . . . . . . . 11
2 background 15
2.1 The Working Group on Open Data in Linguistics (OWLG) 15
2.1.1 The Open Knowledge Foundation . . . . . . . . 15
2.1.2 Goals of the Open Linguistics Working Group . 16
2.1.3 Open linguistics resources, problems and chal-
lenges . . . . . . . . . . . . . . . . . . . . . . . . 17
2.1.4 Recent activities and on-going developments . . 18
2.2 Technological Background . . . . . . . . . . . . . . . . . 18
2.3 RDF as a data model . . . . . . . . . . . . . . . . . . . . 21
2.4 Performance and scalability . . . . . . . . . . . . . . . . 22
2.5 Conceptual interoperability . . . . . . . . . . . . . . . . 22
ii language resources as linked data 25
3 linked data in linguistics 27
3.1 Lexical Resources . . . . . . . . . . . . . . . . . . . . . . 29
3.2 Linguistic Corpora . . . . . . . . . . . . . . . . . . . . . 30
3.3 Linguistic Knowledgebases . . . . . . . . . . . . . . . . 31
3.4 Towards a Linguistic Linked Open Data Cloud . . . . . 32
3.5 State of the Linguistic Linked Open Data Cloud in 2012 33
3.6 Querying linked resources in the LLOD . . . . . . . . . 36
3.6.1 Enriching metadata repositories with linguistic
features (Glottolog â OLiA) . . . . . . . . . . . 36
3.6.2 Enriching lexical-semantic resources with lin-
guistic information (DBpedia (â POWLA) â
OLiA) . . . . . . . . . . . . . . . . . . . . . . . . 38
4 DBpedia as a multilingual language resource:
the case of the greek dbpedia edition. 39
4.1 Current state of the internationalization effort . . . . . 40
4.2 Language-specific design of DBpedia resource identifiers 41
4.3 Inter-DBpedia linking . . . . . . . . . . . . . . . . . . . 42
4.4 Outlook on DBpedia Internationalization . . . . . . . . 44
5 leveraging the crowdsourcing of lexical resources
for bootstrapping a linguistic linked data cloud 47
5.1 Related Work . . . . . . . . . . . . . . . . . . . . . . . . 48
5.2 Problem Description . . . . . . . . . . . . . . . . . . . . 50
5.2.1 Processing Wiki Syntax . . . . . . . . . . . . . . 50
5.2.2 Wiktionary . . . . . . . . . . . . . . . . . . . . . . 52
5.2.3 Wiki-scale Data Extraction . . . . . . . . . . . . . 53
5.3 Design and Implementation . . . . . . . . . . . . . . . . 54
5.3.1 Extraction Templates . . . . . . . . . . . . . . . . 56
5.3.2 Algorithm . . . . . . . . . . . . . . . . . . . . . . 56
5.3.3 Language Mapping . . . . . . . . . . . . . . . . . 58
5.3.4 Schema Mediation by Annotation with lemon . 58
5.4 Resulting Data . . . . . . . . . . . . . . . . . . . . . . . . 58
5.5 Lessons Learned . . . . . . . . . . . . . . . . . . . . . . . 60
5.6 Discussion and Future Work . . . . . . . . . . . . . . . 60
5.6.1 Next Steps . . . . . . . . . . . . . . . . . . . . . . 61
5.6.2 Open Research Questions . . . . . . . . . . . . . 61
6 nlp & dbpedia, an upward knowledge acquisition
spiral 63
6.1 Knowledge acquisition and structuring . . . . . . . . . 64
6.2 Representation of knowledge . . . . . . . . . . . . . . . 65
6.3 NLP tasks and applications . . . . . . . . . . . . . . . . 65
6.3.1 Named Entity Recognition . . . . . . . . . . . . 66
6.3.2 Relation extraction . . . . . . . . . . . . . . . . . 67
6.3.3 Question Answering over Linked Data . . . . . 67
6.4 Resources . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
6.4.1 Gold and silver standards . . . . . . . . . . . . . 69
6.5 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
iii the nlp interchange format (nif) 73
7 nif 2.0 core specification 75
7.1 Conformance checklist . . . . . . . . . . . . . . . . . . . 75
7.2 Creation . . . . . . . . . . . . . . . . . . . . . . . . . . . 76
7.2.1 Definition of Strings . . . . . . . . . . . . . . . . 78
7.2.2 Representation of Document Content with the
nif:Context Class . . . . . . . . . . . . . . . . . . 80
7.3 Extension of NIF . . . . . . . . . . . . . . . . . . . . . . 82
7.3.1 Part of Speech Tagging with OLiA . . . . . . . . 83
7.3.2 Named Entity Recognition with ITS 2.0, DBpe-
dia and NERD . . . . . . . . . . . . . . . . . . . 84
7.3.3 lemon and Wiktionary2RDF . . . . . . . . . . . 86
8 nif 2.0 resources and architecture 89
8.1 NIF Core Ontology . . . . . . . . . . . . . . . . . . . . . 89
8.1.1 Logical Modules . . . . . . . . . . . . . . . . . . 90
8.2 Workflows . . . . . . . . . . . . . . . . . . . . . . . . . . 91
8.2.1 Access via REST Services . . . . . . . . . . . . . 92
8.2.2 NIF Combinator Demo . . . . . . . . . . . . . .
92
8.3 Granularity Profiles . . . . . . . . . . . . . . . . . . . . .
93
8.4 Further URI Schemes for NIF . . . . . . . . . . . . . . .
95
8.4.1 Context-Hash-based URIs . . . . . . . . . . . . .
99
9 evaluation and related work 101
9.1 Questionnaire and Developers Study for NIF 1.0 . . . . 101
9.2 Qualitative Comparison with other Frameworks and
Formats . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102
9.3 URI Stability Evaluation . . . . . . . . . . . . . . . . . . 103
9.4 Related URI Schemes . . . . . . . . . . . . . . . . . . . . 104
iv the nlp interchange format in use 109
10 use cases and applications for nif 111
10.1 Internationalization Tag Set 2.0 . . . . . . . . . . . . . . 111
10.1.1 ITS2NIF and NIF2ITS conversion . . . . . . . . . 112
10.2 OLiA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119
10.3 RDFaCE . . . . . . . . . . . . . . . . . . . . . . . . . . . 120
10.4 Tiger Corpus Navigator . . . . . . . . . . . . . . . . . . 121
10.4.1 Tools and Resources . . . . . . . . . . . . . . . . 122
10.4.2 NLP2RDF in 2010 . . . . . . . . . . . . . . . . . . 123
10.4.3 Linguistic Ontologies . . . . . . . . . . . . . . . . 124
10.4.4 Implementation . . . . . . . . . . . . . . . . . . . 125
10.4.5 Evaluation . . . . . . . . . . . . . . . . . . . . . . 126
10.4.6 Related Work and Outlook . . . . . . . . . . . . 129
10.5 OntosFeeder â a Versatile Semantic Context Provider
for Web Content Authoring . . . . . . . . . . . . . . . . 131
10.5.1 Feature Description and User Interface Walk-
through . . . . . . . . . . . . . . . . . . . . . . . 132
10.5.2 Architecture . . . . . . . . . . . . . . . . . . . . . 134
10.5.3 Embedding Metadata . . . . . . . . . . . . . . . 135
10.5.4 Related Work and Summary . . . . . . . . . . . 135
10.6 RelFinder: Revealing Relationships in RDF Knowledge
Bases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136
10.6.1 Implementation . . . . . . . . . . . . . . . . . . . 137
10.6.2 Disambiguation . . . . . . . . . . . . . . . . . . . 138
10.6.3 Searching for Relationships . . . . . . . . . . . . 139
10.6.4 Graph Visualization . . . . . . . . . . . . . . . . 140
10.6.5 Conclusion . . . . . . . . . . . . . . . . . . . . . . 141
11 publication of corpora using nif 143
11.1 Wikilinks Corpus . . . . . . . . . . . . . . . . . . . . . . 143
11.1.1 Description of the corpus . . . . . . . . . . . . . 143
11.1.2 Quantitative Analysis with Google Wikilinks Cor-
pus . . . . . . . . . . . . . . . . . . . . . . . . . . 144
11.2 RDFLiveNews . . . . . . . . . . . . . . . . . . . . . . . . 144
11.2.1 Overview . . . . . . . . . . . . . . . . . . . . . . 145
11.2.2 Mapping to RDF and Publication on the Web of
Data . . . . . . . . . . . . . . . . . . . . . . . . . 146
v conclusions 149
12 lessons learned, conclusions and future work 151
12.1 Lessons Learned for NIF . . . . . . . . . . . . . . . . . . 151
12.2 Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . 151
12.3 Future Work . . . . . . . . . . . . . . . . . . . . . . . . . 15
European Language Grid
This open access book provides an in-depth description of the EU project European Language Grid (ELG). Its motivation lies in the fact that Europe is a multilingual society with 24 official European Union Member State languages and dozens of additional languages including regional and minority languages. The only meaningful way to enable multilingualism and to benefit from this rich linguistic heritage is through Language Technologies (LT) including Natural Language Processing (NLP), Natural Language Understanding (NLU), Speech Technologies and language-centric Artificial Intelligence (AI) applications. The European Language Grid provides a single umbrella platform for the European LT community, including research and industry, effectively functioning as a virtual home, marketplace, showroom, and deployment centre for all services, tools, resources, products and organisations active in the field. Today the ELG cloud platform already offers access to more than 13,000 language processing tools and language resources. It enables all stakeholders to deposit, upload and deploy their technologies and datasets. The platform also supports the long-term objective of establishing digital language equality in Europe by 2030 â to create a situation in which all European languages enjoy equal technological support. This is the very first book dedicated to Language Technology and NLP platforms. Cloud technology has only recently matured enough to make the development of a platform like ELG feasible on a larger scale. The book comprehensively describes the results of the ELG project. Following an introduction, the content is divided into four main parts: (I) ELG Cloud Platform; (II) ELG Inventory of Technologies and Resources; (III) ELG Community and Initiative; and (IV) ELG Open Calls and Pilot Projects
Clinical practice knowledge acquisition and interrogation using natural language: aquisição e interrogação de conhecimento de prĂĄtica clĂnica usando linguagem natural
Os conceitos cientĂficos, metodologias e ferramentas no sub-dominio da Representação de Conhecimento da ĂĄrea da InteligĂȘncia Artificial Aplicada tĂȘm sofrido avanços muito significativos nos anos recentes. A utilização de Ontologias como conceptualizaçÔes de domĂnios Ă© agora suficientemente poderosa para aspirar ao raciocĂnio computacional sobre realidades complexas. Uma das tarefas cientĂfica e tecnicamente mais desafiante Ă© prestação de cuidados pelos profissionais de saĂșde na especialidade cardiovascular. Um domĂnio de tal forma complexo pode beneficiar largamente da possibilidade de ajudas ao raciocĂnio clĂnico que estĂŁo neste momento a beira de ficarem disponĂveis. Investigamos no sentido de desenvolver uma infraestrutura sĂłlida e completa para a representação de conhecimento na prĂĄtica clĂnica bem como os processes associados para adquirir o conhecimento a partir de textos clĂnicos e raciocinar automaticamente sobre esse conhecimento; ABSTRACT: The scientific concepts, methodologies and tools in the Knowledge Representation (KR) subdomain of applied Artificial Intelligence (AI) came a long way with enormous strides in recent years. The usage of domain conceptualizations that are Ontologies is now powerful enough to aim at computable reasoning over complex realities. One of the most challenging scientific and technical human endeavors is the daily Clinical Practice (CP) of Cardiovascular (C V) specialty healthcare providers. Such a complex domain can beneïŹt largely from the possibility of clinical reasoning aids that are now at the edge of being available. We research into al complete end-to-end solid ontological infrastructure for CP knowledge representation as well as the associated processes to automatically acquire knowledge from clinical texts and reason over it
Aquisição e Interrogação de Conhecimento de PrĂĄtica ClĂnica usando Linguagem Natural
The scientific concepts, methodologies and tools in the Knowledge Representation (KR) sub-
domain of applied Artificial Intelligence (AI) came a long way with enormous strides in recent
years. The usage of domain conceptualizations that are Ontologies is now powerful enough to aim
at computable reasoning over complex realities.
One of the most challenging scientific and technical human endeavors is the daily Clinical Prac-
tice (CP) of Cardiovascular (CV) specialty healthcare providers.
Such a complex domain can benefit largely from the possibility of clinical reasoning aids that are now
at the edge of being available.
We research into a complete end-to-end solid ontological infrastructure for CP knowledge represen-
tation as well as the associated processes to automatically acquire knowledge from clinical texts and
reason over it
European Language Grid
This open access book provides an in-depth description of the EU project European Language Grid (ELG). Its motivation lies in the fact that Europe is a multilingual society with 24 official European Union Member State languages and dozens of additional languages including regional and minority languages. The only meaningful way to enable multilingualism and to benefit from this rich linguistic heritage is through Language Technologies (LT) including Natural Language Processing (NLP), Natural Language Understanding (NLU), Speech Technologies and language-centric Artificial Intelligence (AI) applications. The European Language Grid provides a single umbrella platform for the European LT community, including research and industry, effectively functioning as a virtual home, marketplace, showroom, and deployment centre for all services, tools, resources, products and organisations active in the field. Today the ELG cloud platform already offers access to more than 13,000 language processing tools and language resources. It enables all stakeholders to deposit, upload and deploy their technologies and datasets. The platform also supports the long-term objective of establishing digital language equality in Europe by 2030 â to create a situation in which all European languages enjoy equal technological support. This is the very first book dedicated to Language Technology and NLP platforms. Cloud technology has only recently matured enough to make the development of a platform like ELG feasible on a larger scale. The book comprehensively describes the results of the ELG project. Following an introduction, the content is divided into four main parts: (I) ELG Cloud Platform; (II) ELG Inventory of Technologies and Resources; (III) ELG Community and Initiative; and (IV) ELG Open Calls and Pilot Projects
Conceptualization of Computational Modeling Approaches and Interpretation of the Role of Neuroimaging Indices in Pathomechanisms for Pre-Clinical Detection of Alzheimer Disease
With swift advancements in next-generation sequencing technologies alongside the voluminous growth of biological data, a diversity of various data resources such as databases and web services have been created to facilitate data management, accessibility, and analysis. However, the burden of interoperability between dynamically growing data resources is an increasingly rate-limiting step in biomedicine, specifically concerning neurodegeneration. Over the years, massive investments and technological advancements for dementia research have resulted in large proportions of unmined data. Accordingly, there is an essential need for intelligent as well as integrative approaches to mine available data and substantiate novel research outcomes. Semantic frameworks provide a unique possibility to integrate multiple heterogeneous, high-resolution data resources with semantic integrity using standardized ontologies and vocabularies for context- specific domains. In this current work, (i) the functionality of a semantically structured terminology for mining pathway relevant knowledge from the literature, called Pathway Terminology System, is demonstrated and (ii) a context-specific high granularity semantic framework for neurodegenerative diseases, known as NeuroRDF, is presented. Neurodegenerative disorders are especially complex as they are characterized by widespread manifestations and the potential for dramatic alterations in disease progression over time. Early detection and prediction strategies through clinical pointers can provide promising solutions for effective treatment of AD. In the current work, we have presented the importance of bridging the gap between clinical and molecular biomarkers to effectively contribute to dementia research. Moreover, we address the need for a formalized framework called NIFT to automatically mine relevant clinical knowledge from the literature for substantiating high-resolution cause-and-effect models