MACHINE LEARNING USING SPEECH UTTERANCES FOR PARKINSON DISEASE DETECTION

Pathophysiological recordings of patients measured from various testing methods are frequently used in the medical field for determining symptoms as well as for probability prediction for selected diseases. There are numerous symptoms among the Parkinson’s disease (PD) population, however changes in speech and articulation – is potentially the most significant biomarker. This article is focused on PD diagnosis classification based on their speech signals using pattern recognition methods (AdaBoost, Bagged trees, Quadratic SVM and k-NN). The dataset investigated in the article consists of 30 PD and 30 HC individuals’ voice measurements, with each individual being represented with 2 recordings within the dataset. Training signals for PD and HC underwent an extraction of relatively well-discriminating features relating to energy and spectral speech properties. Model implementations included a 5-fold cross validation. The accuracy of the values obtained employing the models was calculated using the confusion matrix. The average value of the overall accuracy = 82.3 % and averaged AUC = 0.88 (min. AUC = 0.86) on the available data

KOMPLEKSOWE METODY UCZENIA MASZYNOWEGO I UCZENIA GŁĘBOKIEGO DO KLASYFIKACJI CHOROBY PARKINSONA I OCENY JEJ NASILENIA

In this study, we aimed to adopt a comprehensive approach to categorize and assess the severity of Parkinson's disease by leveraging techniques from both machine learning and deep learning. We thoroughly evaluated the effectiveness of various models, including XGBoost, Random Forest, Multi-Layer Perceptron (MLP), and Recurrent Neural Network (RNN), utilizing classification metrics. We generated detailed reports to facilitate a comprehensive comparative analysis of these models. Notably, XGBoost demonstrated the highest precision at 97.4%. Additionally, we took a step further by developing a Gated Recurrent Unit (GRU) model with the purpose of combining predictions from alternative models. We assessed its ability to predict the severity of the ailment. To quantify the precision levels of the models in disease classification, we calculated severity percentages. Furthermore, we created a Receiver Operating Characteristic (ROC) curve for the GRU model, simplifying the evaluation of its capability to distinguish among various severity levels. This comprehensive approach contributes to a more accurate and detailed understanding of Parkinson's disease severity assessment.W tym badaniu naszym celem było przyjęcie kompleksowego podejścia do kategoryzacji i oceny ciężkości choroby Parkinsona poprzez wykorzystanie technik zarówno uczenia maszynowego, jak i głębokiego uczenia. Dokładnie oceniliśmy skuteczność różnych modeli, w tym XGBoost, Random Forest, Multi-Layer Perceptron (MLP) i Recurrent Neural Network (RNN), wykorzystując wskaźniki klasyfikacji. Wygenerowaliśmy szczegółowe raporty, aby ułatwić kompleksową analizę porównawczą tych modeli. Warto zauważyć, że XGBoost wykazał najwyższą precyzję na poziomie 97,4%. Ponadto poszliśmy o krok dalej, opracowując model Gated Recurrent Unit (GRU) w celu połączenia przewidywań z alternatywnych modeli. Oceniliśmy jego zdolność do przewidywania nasilenia dolegliwości. Aby określić ilościowo poziomy dokładności modeli w klasyfikacji chorób, obliczyliśmy wartości procentowe nasilenia. Ponadto stworzyliśmy krzywą charakterystyki operacyjnej odbiornika (ROC) dla modelu GRU, upraszczając ocenę jego zdolności do rozróżniania różnych poziomów nasilenia. To kompleksowe podejście przyczynia się do dokładniejszego i bardziej szczegółowego zrozumienia oceny ciężkości choroby Parkinsona

Intelligent IoT Framework for Indoor Healthcare Monitoring of Parkinson's Disease Patient

Parkinson’s disease is associated with high treatment costs, primarily attributed to the needs of hospitalization and frequent care services. A study reveals annual per-person healthcare costs for Parkinson’s patients to be 21,482,withanadditional29,695 burden to society. Due to the high stakes and rapidly rising Parkinson’s patients’ count, it is imperative to introduce intelligent monitoring and analysis systems. In this paper, an Internet of Things (IoT) based framework is proposed to enable remote monitoring, administration, and analysis of patient’s conditions in a typical indoor environment. The proposed infrastructure offers both static and dynamic routing, along with delay analysis and priority enabled communications. The scheme also introduces machine learning techniques to detect the progression of Parkinson’s over six months using auditory inputs. The proposed IoT infrastructure and machine learning algorithm are thoroughly evaluated and a detailed analysis is performed. The results show that the proposed scheme offers efficient communication scheduling, facilitating a high number of users with low latency. The proposed machine learning scheme also outperforms state-of-the-art techniques in accurately predicting the Parkinson’s progression

Identification of diseases based on the use of inertial sensors: a systematic review

Inertial sensors are commonly embedded in several devices, including smartphones, and other specific devices. This type of sensors may be used for different purposes, including the recognition of different diseases. Several studies are focused on the use of accelerometer for the automatic recognition of different diseases, and it may powerful the different treatments with the use of less invasive and painful techniques for patients. This paper is focused in the systematic review of the studies available in the literature for the automatic recognition of different diseases with accelerometer sensors. The disease that is the most reliably detectable disease using accelerometer sensors, available in 54% of the analyzed studies, is the Parkinson’s disease. The machine learning methods implements for the recognition of Parkinson’s disease reported an accuracy of 94%. Other diseases are recognized in less number that will be subject of further analysis in the future.info:eu-repo/semantics/publishedVersio

Brain neural network, development, microbiome, microbial toxins and COVID-19

Although almost 2 years have passed since the beginning of the coronavirus disease 2019 (COVID-19) pandemic in the world, there is still a threat to the health of people at risk and patients. Specialists in various sciences conduct various researches in order to eliminate or reduce the problems caused by this disease. Neural network science plays a vital role in this regard. It is important to note the key points of neuro-microbial involvement in the diagnosis and management of COVID-19 therapy by physicians and patients whose nervous systems are challenged. The relationship between COVID-19, microbiome and the profile of microbial toxins in the body is one of the factors that can directly or indirectly play a key role in the body's resistance to Covid-19 and changes in the neural network of the brain. In this article, we introduce the relationship and behavioral and mood problems that can result from neuronal changes. In linking the components of this network, artificial intelligence (AI), machine learning (ML) and data mining (DM) can be important strategies to assist health providers to choose best decision based on patient’s history.

Fog Data: Enhancing Telehealth Big Data Through Fog Computing

The size of multi-modal, heterogeneous data collected through various sensors is growing exponentially. It demands intelligent data reduction, data mining and analytics at edge devices. Data compression can reduce the network bandwidth and transmission power consumed by edge devices. This paper proposes, validates and evaluates Fog Data, a service-oriented architecture for Fog computing. The center piece of the proposed architecture is a low power embedded computer that carries out data mining and data analytics on raw data collected from various wearable sensors used for telehealth applications. The embedded computer collects the sensed data as time series, analyzes it, and finds similar patterns present. Patterns are stored, and unique patterns are transmited. Also, the embedded computer extracts clinically relevant information that is sent to the cloud. A working prototype of the proposed architecture was built and used to carry out case studies on telehealth big data applications. Specifically, our case studies used the data from the sensors worn by patients with either speech motor disorders or cardiovascular problems. We implemented and evaluated both generic and application specific data mining techniques to show orders of magnitude data reduction and hence transmission power savings. Quantitative evaluations were conducted for comparing various data mining techniques and standard data compression techniques. The obtained results showed substantial improvement in system efficiency using the Fog Data architecture

An intelligent information forwarder for healthcare big data systems with distributed wearable sensors

© 2016 IEEE. An increasing number of the elderly population wish to live an independent lifestyle, rather than rely on intrusive care programmes. A big data solution is presented using wearable sensors capable of carrying out continuous monitoring of the elderly, alerting the relevant caregivers when necessary and forwarding pertinent information to a big data system for analysis. A challenge for such a solution is the development of context-awareness through the multidimensional, dynamic and nonlinear sensor readings that have a weak correlation with observable human behaviours and health conditions. To address this challenge, a wearable sensor system with an intelligent data forwarder is discussed in this paper. The forwarder adopts a Hidden Markov Model for human behaviour recognition. Locality sensitive hashing is proposed as an efficient mechanism to learn sensor patterns. A prototype solution is implemented to monitor health conditions of dispersed users. It is shown that the intelligent forwarders can provide the remote sensors with context-awareness. They transmit only important information to the big data server for analytics when certain behaviours happen and avoid overwhelming communication and data storage. The system functions unobtrusively, whilst giving the users peace of mind in the knowledge that their safety is being monitored and analysed

Discovering the Symptom Patterns of COVID-19 from Recovered and Deceased Patients Using Apriori Association Rule Mining

The COVID-19 pandemic has a devastating impact globally, claiming millions of lives and causing significant social and economic disruptions. In order to optimize decision-making and allocate limited resources, it is essential to identify COVID-19 symptoms and determine the severity of each case. Machine learning algorithms offer a potent tool in the medical field, particularly in mining clinical datasets for useful information and guiding scientific decisions. Association rule mining is a machine learning technique for extracting hidden patterns from data. This paper presents an application of association rule mining based Apriori algorithm to discover symptom patterns from COVID-19 patients. The study, using 2875 records of patient, identified the most common symptoms as apnea (72%), cough (64%), fever (59%), weakness (18%), myalgia (14.5%), and sore throat (12%). The proposed method provides clinicians with valuable insight into disease that can assist them in managing and treating it effectively

Thirty years of artificial intelligence in medicine (AIME) conferences: A review of research themes

Over the past 30 years, the international conference on Artificial Intelligence in MEdicine (AIME) has been organized at different venues across Europe every 2 years, establishing a forum for scientific exchange and creating an active research community. The Artificial Intelligence in Medicine journal has published theme issues with extended versions of selected AIME papers since 1998