A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Machine Learning Methods for Image Analysis in Medical Applications, from Alzheimer\u27s Disease, Brain Tumors, to Assisted Living

Healthcare has progressed greatly nowadays owing to technological advances, where machine learning plays an important role in processing and analyzing a large amount of medical data. This thesis investigates four healthcare-related issues (Alzheimer\u27s disease detection, glioma classification, human fall detection, and obstacle avoidance in prosthetic vision), where the underlying methodologies are associated with machine learning and computer vision. For Alzheimer’s disease (AD) diagnosis, apart from symptoms of patients, Magnetic Resonance Images (MRIs) also play an important role. Inspired by the success of deep learning, a new multi-stream multi-scale Convolutional Neural Network (CNN) architecture is proposed for AD detection from MRIs, where AD features are characterized in both the tissue level and the scale level for improved feature learning. Good classification performance is obtained for AD/NC (normal control) classification with test accuracy 94.74%. In glioma subtype classification, biopsies are usually needed for determining different molecular-based glioma subtypes. We investigate non-invasive glioma subtype prediction from MRIs by using deep learning. A 2D multi-stream CNN architecture is used to learn the features of gliomas from multi-modal MRIs, where the training dataset is enlarged with synthetic brain MRIs generated by pairwise Generative Adversarial Networks (GANs). Test accuracy 88.82% has been achieved for IDH mutation (a molecular-based subtype) prediction. A new deep semi-supervised learning method is also proposed to tackle the problem of missing molecular-related labels in training datasets for improving the performance of glioma classification. In other two applications, we also address video-based human fall detection by using co-saliency-enhanced Recurrent Convolutional Networks (RCNs), as well as obstacle avoidance in prosthetic vision by characterizing obstacle-related video features using a Spiking Neural Network (SNN). These investigations can benefit future research, where artificial intelligence/deep learning may open a new way for real medical applications

Explainable artificial intelligence (XAI) in deep learning-based medical image analysis

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial Intelligence (XAI) used in deep learning-based medical image analysis. A framework of XAI criteria is introduced to classify deep learning-based medical image analysis methods. Papers on XAI techniques in medical image analysis are then surveyed and categorized according to the framework and according to anatomical location. The paper concludes with an outlook of future opportunities for XAI in medical image analysis.Comment: Submitted for publication. Comments welcome by email to first autho

U-Capkidnets++-: A Novel Hybrid Capsule Networks with Optimized Deep Feed Forward Networks for an Effective Classification of Kidney Tumours Using CT Kidney Images

Chronic Kidney Diseases (CKD) has become one among the world wide health crisis and needs the associated efforts to prevent the complete organ damage. A considerable research effort has been put forward onto the effective seperation and classification of kidney tumors from the kidney CT Images. Emerging machine learning along with deep learning algorithms have waved the novel paths of tumor detections. But these methods are proved to be laborious and its success rate is purely depends on the previous experiences. To achieve the better classification and segmentation of tumors, this paper proposes the hybrid ensemble of visual capsule networks in U-NET deep learning architecture and w deep feed-forward extreme learning machines. The proposed framework incorporates the data-preprocessing powerful data augmentation, saliency tumor segmentation (STS) followed by the classification phase. Furthermore, classification levels are constructed based upon the feed forward extreme learning machines (FFELM) to enhance the effectiveness of the suggested model .The extensive experimentation has been conducted to evaluate the efficacy of the recommended structure and matched with the other prevailing hybrid deep learning model. Experimentation demonstrates that the suggested model has showed the superior predominance over the other models and exhibited DICE co-efficient of kidney tumors as high as 0.96 and accuracy of 97.5 %respectively