Respiratory Compensated Robot for Liver Cancer Treatment: Design, Fabrication, and Benchtop Characterization

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death in the world. Radiofrequency ablation (RFA) is an effective method for treating tumors less than 5 cm. However, manually placing the RFA needle at the site of the tumor is challenging due to the complicated respiratory induced motion of the liver. This paper presents the design, fabrication, and benchtop characterization of a patient mounted, respiratory compensated robotic needle insertion platform to perform percutaneous needle interventions. The robotic platform consists of a 4-DoF dual-stage cartesian platform used to control the pose of a 1-DoF needle insertion module. The active needle insertion module consists of a 3D printed flexible fluidic actuator capable of providing a step-like, grasp-insert-release actuation that mimics the manual insertion procedure. Force characterization of the needle insertion module indicates that the device is capable of producing 22.6 ± 0.40 N before the needle slips between the grippers. Static phantom targeting experiments indicate a positional error of 1.14 ± 0.30 mm and orientational error of 0.99° ± 0.36°. Static ex-vivo porcine liver targeting experiments indicate a positional error of 1.22 ± 0.31 mm and orientational error of 1.16° ± 0.44°. Dynamic targeting experiments with the proposed active motion compensation in dynamic phantom and ex-vivo porcine liver show 66.3% and 69.6% positional accuracy improvement, respectively. Future work will continue to develop this platform with the long-term goal of applying the system to RFA for HCC

Annual Report 2018-2019

LETTER FROM THE DEAN I am pleased to share with you the 2018-19 College of Computing and Digital Media (CDM) annual report, highlighting the important work done by our faculty, students, and staff. We’ve said this before, and we’ll say it again: it was a big year. In 2018-19, programs across all three of our schools (Computing, Cinematic Arts, and Design) were ranked nationally. Our faculty were published in dozens of scholarly journals, screened their films over 100 times, and had their work exhibited globally. Student and alumni accomplishments included an Emmy nomination, a first place win in a Department of Energy competition, and features in trade publications--to name just a few. We worked to create new programs (including undergraduate and graduate comedy filmmaking programs in collaboration with The Second City) and continued our work in others (our NSF- funded Medical Informatics Experiences program celebrated its fifteenth year). Our makerspace, the Idea Realization Lab, clocked its 10,000th visit as we made plans to open a new IRL in Lincoln Park. And, we will continue to create the innovative programs and facilities that make us CDM. You can look forward to new programs like industrial design, and new labs that focus on everything from Internet of Things to design industry collaborations. I am proud of our CDM community, and I hope you feel that same sense of pride as you read through this report. David MillerDeanhttps://via.library.depaul.edu/cdmannual/1002/thumbnail.jp

Medical-Data-Models.org:A collection of freely available forms (September 2016)

MDM-Portal (Medical Data-Models) is a meta-data repository for creating, analysing, sharing and reusing medical forms, developed by the Institute of Medical Informatics, University of Muenster in Germany. Electronic forms for documentation of patient data are an integral part within the workflow of physicians. A huge amount of data is collected either through routine documentation forms (EHRs) for electronic health records or as case report forms (CRFs) for clinical trials. This raises major scientific challenges for health care, since different health information systems are not necessarily compatible with each other and thus information exchange of structured data is hampered. Software vendors provide a variety of individual documentation forms according to their standard contracts, which function as isolated applications. Furthermore, free availability of those forms is rarely the case. Currently less than 5 % of medical forms are freely accessible. Based on this lack of transparency harmonization of data models in health care is extremely cumbersome, thus work and know-how of completed clinical trials and routine documentation in hospitals are hard to be re-used. The MDM-Portal serves as an infrastructure for academic (non-commercial) medical research to contribute a solution to this problem. It already contains more than 4,000 system-independent forms (CDISC ODM Format, www.cdisc.org, Operational Data Model) with more than 380,000 dataelements. This enables researchers to view, discuss, download and export forms in most common technical formats such as PDF, CSV, Excel, SQL, SPSS, R, etc. A growing user community will lead to a growing database of medical forms. In this matter, we would like to encourage all medical researchers to register and add forms and discuss existing forms

日本医科大学研究業績年報 第60巻 平成25(2013年度)

日本医科大