MDE in Practice for Computational Science

International audienceThe complex problems that computational science addresses are more and more benefiting from the progress of computing facilities (simulators, librairies, accessible languages,. . .). Nevertheless , the actual solutions call for several improvements. Among those, we address in this paper the needs for leveraging on knowledge and expertise by focusing on Domain-Specific Mod-eling Languages application. In this vision paper we illustrate, through concrete experiments, how the last DSML research help getting closer the problem and implementation spaces

Models in the Cloud: Exploring Next Generation Environmental Software Systems

There is growing interest in the application of the latest trends in computing and data science methods to improve environmental science. However we found the penetration of best practice from computing domains such as software engineering and cloud computing into supporting every day environmental science to be poor. We take from this work a real need to re-evaluate the complexity of software tools and bring these to the right level of abstraction for environmental scientists to be able to leverage the latest developments in computing. In the Models in the Cloud project, we look at the role of model driven engineering, software frameworks and cloud computing in achieving this abstraction. As a case study we deployed a complex weather model to the cloud and developed a collaborative notebook interface for orchestrating the deployment and analysis of results. We navigate relatively poor support for complex high performance computing in the cloud to develop abstractions from complexity in cloud deployment and model configuration. We found great potential in cloud computing to transform science by enabling models to leverage elastic, flexible computing infrastructure and support new ways to deliver collaborative and open science

Kevoree Modeling Framework (KMF): Efficient modeling techniques for runtime use

The creation of Domain Specific Languages(DSL) counts as one of the main goals in the field of Model-Driven Software Engineering (MDSE). The main purpose of these DSLs is to facilitate the manipulation of domain specific concepts, by providing developers with specific tools for their domain of expertise. A natural approach to create DSLs is to reuse existing modeling standards and tools. In this area, the Eclipse Modeling Framework (EMF) has rapidly become the defacto standard in the MDSE for building Domain Specific Languages (DSL) and tools based on generative techniques. However, the use of EMF generated tools in domains like Internet of Things (IoT), Cloud Computing or Models@Runtime reaches several limitations. In this paper, we identify several properties the generated tools must comply with to be usable in other domains than desktop-based software systems. We then challenge EMF on these properties and describe our approach to overcome the limitations. Our approach, implemented in the Kevoree Modeling Framework (KMF), is finally evaluated according to the identified properties and compared to EMF.Comment: ISBN 978-2-87971-131-7; N° TR-SnT-2014-11 (2014

Making up for the deficit in a marathon run

To predict the final result of an athlete in a marathon run thoroughly is the eternal desire of each trainer. Usually, the achieved result is weaker than the predicted one due to the objective (e.g., environmental conditions) as well as subjective factors (e.g., athlete's malaise). Therefore, making up for the deficit between predicted and achieved results is the main ingredient of the analysis performed by trainers after the competition. In the analysis, they search for parts of a marathon course where the athlete lost time. This paper proposes an automatic making up for the deficit by using a Differential Evolution algorithm. In this case study, the results that were obtained by a wearable sports-watch by an athlete in a real marathon are analyzed. The first experiments with Differential Evolution show the possibility of using this method in the future.Comment: ISMSI 201

An Exploratory Study of Forces and Frictions affecting Large-Scale Model-Driven Development

In this paper, we investigate model-driven engineering, reporting on an exploratory case-study conducted at a large automotive company. The study consisted of interviews with 20 engineers and managers working in different roles. We found that, in the context of a large organization, contextual forces dominate the cognitive issues of using model-driven technology. The four forces we identified that are likely independent of the particular abstractions chosen as the basis of software development are the need for diffing in software product lines, the needs for problem-specific languages and types, the need for live modeling in exploratory activities, and the need for point-to-point traceability between artifacts. We also identified triggers of accidental complexity, which we refer to as points of friction introduced by languages and tools. Examples of the friction points identified are insufficient support for model diffing, point-to-point traceability, and model changes at runtime.Comment: To appear in proceedings of MODELS 2012, LNCS Springe

Computer simulation of glioma growth and morphology

Despite major advances in the study of glioma, the quantitative links between intra-tumor molecular/cellular properties, clinically observable properties such as morphology, and critical tumor behaviors such as growth and invasiveness remain unclear, hampering more effective coupling of tumor physical characteristics with implications for prognosis and therapy. Although molecular biology, histopathology, and radiological imaging are employed in this endeavor, studies are severely challenged by the multitude of different physical scales involved in tumor growth, i.e., from molecular nanoscale to cell microscale and finally to tissue centimeter scale. Consequently, it is often difficult to determine the underlying dynamics across dimensions. New techniques are needed to tackle these issues. Here, we address this multi-scalar problem by employing a novel predictive three-dimensional mathematical and computational model based on first-principle equations (conservation laws of physics) that describe mathematically the diffusion of cell substrates and other processes determining tumor mass growth and invasion. The model uses conserved variables to represent known determinants of glioma behavior, e.g., cell density and oxygen concentration, as well as biological functional relationships and parameters linking phenomena at different scales whose specific forms and values are hypothesized and calculated based on in vitro and in vivo experiments and from histopathology of tissue specimens from human gliomas. This model enables correlation of glioma morphology to tumor growth by quantifying interdependence of tumor mass on the microenvironment (e.g., hypoxia, tissue disruption) and on the cellular phenotypes (e.g., mitosis and apoptosis rates, cell adhesion strength). Once functional relationships between variables and associated parameter values have been informed, e.g., from histopathology or intra-operative analysis, this model can be used for disease diagnosis/prognosis, hypothesis testing, and to guide surgery and therapy. In particular, this tool identifies and quantifies the effects of vascularization and other cell-scale glioma morphological characteristics as predictors of tumor-scale growth and invasion