Topics in genomic image processing

The image processing methodologies that have been actively studied and developed now play a very significant role in the flourishing biotechnology research. This work studies, develops and implements several image processing techniques for M-FISH and cDNA microarray images. In particular, we focus on three important areas: M-FISH image compression, microarray image processing and expression-based classification. Two schemes, embedded M-FISH image coding (EMIC) and Microarray BASICA: Background Adjustment, Segmentation, Image Compression and Analysis, have been introduced for M-FISH image compression and microarray image processing, respectively. In the expression-based classification area, we investigate the relationship between optimal number of features and sample size, either analytically or through simulation, for various classifiers

Progressive transmission of medical images

A novel adaptive source-channel coding scheme for progressive transmission of medical images with a feedback system is therefore proposed in this dissertation. The overall design includes Discrete Wavelet Transform (DWT), Embedded Zerotree Wavelet (EZW) coding, Joint Source-Channel Coding (JSCC), prioritization of region of interest (RoI), variability of parity length based on feedback, and the corresponding hardware design utilising Simulink. The JSCC can achieve an efficient transmission by incorporating unequal error projection (UEP) and rate allocation. An algorithm is also developed to estimate the number of erroneous data in the receiver. The algorithm detects the address in which the number of symbols for each subblock is indicated, and reassigns an estimated correct data according to a decision making criterion, if error data is detected. The proposed system has been designed based on Simulink which can be used to generate netlist for portable devices. A new compression method called Compressive Sensing (CS) is also revisited in this work. CS exhibits many advantages in comparison with EZW based on our experimental results. DICOM JPEG2000 is an efficient coding standard for lossy or lossless multi-component image coding. However, it does not provide any mechanism for automatic RoI definition, and is more complex compared to our proposed scheme. The proposed system significantly reduces the transmission time, lowers computation cost, and maintains an error-free state in the RoI with regards to the above provided features. A MATLAB-based TCP/IP connection is established to demonstrate the efficacy of the proposed interactive and adaptive progressive transmission system. The proposed system is simulated for both binary and symmetric channel (BSC) and Rayleigh channel. The experimental results confirm the effectiveness of the design.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Progressive transmission of medical images

A novel adaptive source-channel coding scheme for progressive transmission of medical images with a feedback system is therefore proposed in this dissertation. The overall design includes Discrete Wavelet Transform (DWT), Embedded Zerotree Wavelet (EZW) coding, Joint Source-Channel Coding (JSCC), prioritization of region of interest (RoI), variability of parity length based on feedback, and the corresponding hardware design utilising Simulink. The JSCC can achieve an efficient transmission by incorporating unequal error projection (UEP) and rate allocation. An algorithm is also developed to estimate the number of erroneous data in the receiver. The algorithm detects the address in which the number of symbols for each subblock is indicated, and reassigns an estimated correct data according to a decision making criterion, if error data is detected. The proposed system has been designed based on Simulink which can be used to generate netlist for portable devices. A new compression method called Compressive Sensing (CS) is also revisited in this work. CS exhibits many advantages in comparison with EZW based on our experimental results. DICOM JPEG2000 is an efficient coding standard for lossy or lossless multi-component image coding. However, it does not provide any mechanism for automatic RoI definition, and is more complex compared to our proposed scheme. The proposed system significantly reduces the transmission time, lowers computation cost, and maintains an error-free state in the RoI with regards to the above provided features. A MATLAB-based TCP/IP connection is established to demonstrate the efficacy of the proposed interactive and adaptive progressive transmission system. The proposed system is simulated for both binary and symmetric channel (BSC) and Rayleigh channel. The experimental results confirm the effectiveness of the desig