Use of nonintrusive sensor-based information and communication technology for real-world evidence for clinical trials in dementia

Cognitive function is an important end point of treatments in dementia clinical trials. Measuring cognitive function by standardized tests, however, is biased toward highly constrained environments (such as hospitals) in selected samples. Patient-powered real-world evidence using information and communication technology devices, including environmental and wearable sensors, may help to overcome these limitations. This position paper describes current and novel information and communication technology devices and algorithms to monitor behavior and function in people with prodromal and manifest stages of dementia continuously, and discusses clinical, technological, ethical, regulatory, and user-centered requirements for collecting real-world evidence in future randomized controlled trials. Challenges of data safety, quality, and privacy and regulatory requirements need to be addressed by future smart sensor technologies. When these requirements are satisfied, these technologies will provide access to truly user relevant outcomes and broader cohorts of participants than currently sampled in clinical trials

Real-time human ambulation, activity, and physiological monitoring:taxonomy of issues, techniques, applications, challenges and limitations

Automated methods of real-time, unobtrusive, human ambulation, activity, and wellness monitoring and data analysis using various algorithmic techniques have been subjects of intense research. The general aim is to devise effective means of addressing the demands of assisted living, rehabilitation, and clinical observation and assessment through sensor-based monitoring. The research studies have resulted in a large amount of literature. This paper presents a holistic articulation of the research studies and offers comprehensive insights along four main axes: distribution of existing studies; monitoring device framework and sensor types; data collection, processing and analysis; and applications, limitations and challenges. The aim is to present a systematic and most complete study of literature in the area in order to identify research gaps and prioritize future research directions

Design And Implementation Of An Autonomous Wireless Sensor-Based Smart Home

The Smart home has gained widespread attentions due to its flexible integration into everyday life. This next generation of green home system transparently unifies various home appliances, smart sensors and wireless communication technologies. It can integrate diversified physical sensed information and control various consumer home devices, with the support of active sensor networks having both sensor and actuator components. Although smart homes are gaining popularity due to their energy saving and better living benefits, there is no standardized design for smart homes. In this thesis, a smart home design is put forward that can classify and predict the state of the home utilizing historical data of the home. A wireless sensor network was setup in a home to gather and send data to a sink node. The collected data was utilized to train and test a classification model achieving high accuracy with Support Vector Machine (SVM). SVM was further utilized as a predictor of future home states. Based on the data collection, classification and prediction models, a system was designed that can learn, run with minimal human supervision and detect anomalies in a home. The aforementioned attributes make the system an asset for senior care scenarios

Unobtrusive Health Monitoring in Private Spaces: The Smart Home

With the advances in sensor technology, big data, and artificial intelligence, unobtrusive in-home health monitoring has been a research focus for decades. Following up our research on smart vehicles, within the framework of unobtrusive health monitoring in private spaces, this work attempts to provide a guide to current sensor technology for unobtrusive in-home monitoring by a literature review of the state of the art and to answer, in particular, the questions: (1) What types of sensors can be used for unobtrusive in-home health data acquisition? (2) Where should the sensors be placed? (3) What data can be monitored in a smart home? (4) How can the obtained data support the monitoring functions? We conducted a retrospective literature review and summarized the state-of-the-art research on leveraging sensor technology for unobtrusive in-home health monitoring. For structured analysis, we developed a four-category terminology (location, unobtrusive sensor, data, and monitoring functions). We acquired 912 unique articles from four relevant databases (ACM Digital Lib, IEEE Xplore, PubMed, and Scopus) and screened them for relevance, resulting in n=55 papers analyzed in a structured manner using the terminology. The results delivered 25 types of sensors (motion sensor, contact sensor, pressure sensor, electrical current sensor, etc.) that can be deployed within rooms, static facilities, or electric appliances in an ambient way. While behavioral data (e.g., presence (n=38), time spent on activities (n=18)) can be acquired effortlessly, physiological parameters (e.g., heart rate, respiratory rate) are measurable on a limited scale (n=5). Behavioral data contribute to functional monitoring. Emergency monitoring can be built up on behavioral and environmental data. Acquired physiological parameters allow reasonable monitoring of physiological functions to a limited extent. Environmental data and behavioral data also detect safety and security abnormalities. Social interaction monitoring relies mainly on direct monitoring of tools of communication (smartphone; computer). In summary, convincing proof of a clear effect of these monitoring functions on clinical outcome with a large sample size and long-term monitoring is still lacking

On-line Human Activity Recognition from Audio and Home Automation Sensors: comparison of sequential and non-sequential models in realistic Smart Homes

International audienceAutomatic human Activity Recognition (AR) is an important process for the provision of context-aware services in smart spaces such as voice-controlled smart homes. In this paper, we present an on-line Activities of Daily Living (ADL) recognition method for automatic identification within homes in which multiple sensors, actuators and automation equipment coexist, including audio sensors. Three sequence-based models are presented and compared: a Hidden Markov Model (HMM), Conditional Random Fields (CRF) and a sequential Markov Logic Network (MLN). These methods have been tested in two real Smart Homes thanks to experiments involving more than 30 participants. Their results were compared to those of three non-sequential models: a Support Vector Machine (SVM), a Random Forest (RF) and a non-sequential MLN. This comparative study shows that CRF gave the best results for on-line activity recognition from non-visual, audio and home automation sensors

A Home Security System Based on Smartphone Sensors

Several new smartphones are released every year. Many people upgrade to new phones, and their old phones are not put to any further use. In this paper, we explore the feasibility of using such retired smartphones and their on-board sensors to build a home security system. We observe that door-related events such as opening and closing have unique vibration signatures when compared to many types of environmental vibrational noise. These events can be captured by the accelerometer of a smartphone when the phone is mounted on a wall near a door. The rotation of a door can also be captured by the magnetometer of a smartphone when the phone is mounted on a door. We design machine learning and threshold-based methods to detect door opening events based on accelerometer and magnetometer data and build a prototype home security system that can detect door openings and notify the homeowner via email, SMS and phone calls upon break-in detection. To further augment our security system, we explore using the smartphone’s built-in microphone to detect door and window openings across multiple doors and windows simultaneously. Experiments in a residential home show that the accelerometer- based detection can detect door open events with an accuracy higher than 98%, and magnetometer-based detection has 100% accuracy. By using the magnetometer method to automate the training phase of a neural network, we find that sound-based detection of door openings has an accuracy of 90% across multiple doors

SoK: Acoustic Side Channels

We provide a state-of-the-art analysis of acoustic side channels, cover all the significant academic research in the area, discuss their security implications and countermeasures, and identify areas for future research. We also make an attempt to bridge side channels and inverse problems, two fields that appear to be completely isolated from each other but have deep connections.Comment: 16 page