Metascientific views: Challenge and opportunity for philosophy of biology in practice

In this paper I take evolutionary biology as an example to reflect on the role of philosophy and on the transformations that philosophy is constantly stimulated to do in its own approach when dealing with science. I consider that some intellectual movements within evolutionary biology (more specifically, the various calls for 'synthesis') express metascientific views, i.e., claims about 'what it is to do research' in evolutionary biology at different times. In the construction of metascientific views I see a fundamental role to be played by philosophy, and, at the same time, a need to complement the philosophical methods with many more methods coming from other sciences. What leads philosophy out of itself is its own attention to scientific practice. My humble methodological suggestions are, at this stage, only meant to help us imagine metascientific views that are built with a more scientific, interdisciplinary approach, in order to attenuate partiality, subjectivity and impressionism in describing the scientific community. And yet, we should not be naïve and imbued with the myth of 'datadriven' research, especially in this field: other complex issues about metascientific views call for a serious, constant philosophical reflection on scientific practice

Creating a Comprehensive Search Strategy for Research on Learning Disabilities Using the Pearl Harvesting Information Retrieval Framework

The migration of libraries to the digital realm has created new opportunities for information sharing; however, the abundance of available literature has made locating relevant research studies on specific learning disabilities a difficult task, one that existing search strategies have not adequately addressed. Moreover, definitions of specific learning disabilities have evolved and the nature of this field is interdisciplinary, creating a confusion of possible search terms for the topic. The present investigation used the Pearl Harvesting Information Retrieval Framework to create a comprehensive search strategy for locating research on learning disabilities. The analysis produced four groups of harvested search terms for the subtopics of general learning disabilities, reading disabilities, math disabilities, and nonverbal learning disabilities. The wide range of diverse search terms retrieved a significantly greater number of relevant citations than other search strategies

A Conceptual Model for Scholarly Research Activity

This paper presents a conceptual model for scholarly research activity, developed as part of the conceptual modelling work within the ???Preparing DARIAH??? European e-Infrastructures project. It is inspired by cultural-historical activity theory, and is expressed in terms of the CIDOC Conceptual Reference Model, extending its notion of activity so as to also account, apart from historical practice, for scholarly research planning. It is intended as a framework for structuring and analyzing the results of empirical research on scholarly practice and information requirements, encompassing the full research lifecycle of information work and involving both primary evidence and scholarly objects; also, as a framework for producing clear and pertinent information requirements, and specifications of digital infrastructures, tools and services for scholarly research. We plan to use the model to tag interview transcripts from an empirical study on scholarly information work, and thus validate its soundness and fitness for purpose

Information retrieval in systematic reviews: a case study of the crime prevention literature

OBJECTIVES: A defining feature of a systematic review is the data collection; the assembling of a meticulous, unbiased, and reproducible set of primary studies. This requires specialist skills to execute. The aim of this paper is to marshal tacit knowledge, gained through a systematic search of the crime prevention literature, to develop a ‘how-to guide’ for future evidence synthesists in allied fields. METHODS: Empirical results from a recent systematic search for evidence in crime prevention are supplied to illustrate key principles of information retrieval. RESULTS: Difficulties in operationalizing a systematic search are expounded and possible solutions discussed. Empirical results from optimizing the balance between sensitivity and precision with the criminological literature are presented. An estimation of database overlap for crime prevention studies is provided to guide other evidence synthesists in streamlining the search process. CONCLUSIONS: A high-quality search will involve a substantial time investment in honing the research question, specifying the precise scope of the work, and trialing and testing of search tactics. Electronic databases are a lucrative source of eligible studies, but they have important limitations. The diversity of expression across the criminological literature needs to be captured by the use of many search terms—both natural language and controlled vocabulary—in database searches. Complementary search tactics should be employed to locate eligible studies without common vocabulary. Grey literature should be ardently pursued, for it has a central role in the crime prevention evidence base

Evaluating Research and Impact: A Bibliometric Analysis of Research by the NIH/NIAID HIV/AIDS Clinical Trials Networks

Evaluative bibliometrics uses advanced techniques to assess the impact of scholarly work in the context of other scientific work and usually compares the relative scientific contributions of research groups or institutions. Using publications from the National Institute of Allergy and Infectious Diseases (NIAID) HIV/AIDS extramural clinical trials networks, we assessed the presence, performance, and impact of papers published in 2006–2008. Through this approach, we sought to expand traditional bibliometric analyses beyond citation counts to include normative comparisons across journals and fields, visualization of co-authorship across the networks, and assess the inclusion of publications in reviews and syntheses. Specifically, we examined the research output of the networks in terms of the a) presence of papers in the scientific journal hierarchy ranked on the basis of journal influence measures, b) performance of publications on traditional bibliometric measures, and c) impact of publications in comparisons with similar publications worldwide, adjusted for journals and fields. We also examined collaboration and interdisciplinarity across the initiative, through network analysis and modeling of co-authorship patterns. Finally, we explored the uptake of network produced publications in research reviews and syntheses. Overall, the results suggest the networks are producing highly recognized work, engaging in extensive interdisciplinary collaborations, and having an impact across several areas of HIV-related science. The strengths and limitations of the approach for evaluation and monitoring research initiatives are discussed

Effect and timing of operative treatment for teratoma associated N-Methyl-d-Aspartate receptor-antibody encephalitis: A systematic review with meta-analysis

Resection of an underlying ovarian teratoma in patients with N-Methyl-d-Aspartate receptor (NMDAR)-antibody encephalitis is supported by pathophysiological studies demonstrating the production of NMDAR antibodies within the teratoma. This systematic review assesses the clinical effect of teratoma resection and compares early versus late resection. Literature search was performed on the first of October 2022 (MEDLINE, Embase, CENTRAL, Web of Science). Original studies including more than three patients with NDMAR encephalitis and associated ovarian teratoma were included and evaluated with the Study Quality Assessment Tool for risk of bias. Fourteen studies referring to 1499 patients were included and analyzed in four syntheses using the fixed Mantel-Haenszel method. The rate of relapse in patients with ovarian teratoma resection was lower than in patients without resection (risk ratio for relapse 0.30, 95% CI 0.17-0.51), however the certainty level of evidence is very low. Despite some evidence pointing to a beneficial effect of early teratoma resection in patients with NMDAR-antibody encephalitis, systematically accessible data are insufficient to provide recommendations for or against resection, as well as for timing of surgery. The authors received no financial support for the research, authorship, or publication of this article. For the systematic review no clinical-trial database registration had been done

The Extraction of Community Structures from Publication Networks to Support Ethnographic Observations of Field Differences in Scientific Communication

The scientific community of researchers in a research specialty is an important unit of analysis for understanding the field specific shaping of scientific communication practices. These scientific communities are, however, a challenging unit of analysis to capture and compare because they overlap, have fuzzy boundaries, and evolve over time. We describe a network analytic approach that reveals the complexities of these communities through examination of their publication networks in combination with insights from ethnographic field studies. We suggest that the structures revealed indicate overlapping sub- communities within a research specialty and we provide evidence that they differ in disciplinary orientation and research practices. By mapping the community structures of scientific fields we aim to increase confidence about the domain of validity of ethnographic observations as well as of collaborative patterns extracted from publication networks thereby enabling the systematic study of field differences. The network analytic methods presented include methods to optimize the delineation of a bibliographic data set in order to adequately represent a research specialty, and methods to extract community structures from this data. We demonstrate the application of these methods in a case study of two research specialties in the physical and chemical sciences.Comment: Accepted for publication in JASIS