Optimization of a hardware/software coprocessing platform for EEG eyeblink detection and removal

The feasibility of implementing a real-time system for removing eyeblink artifacts from electroencephalogram (EEG) recordings utilizing a hardware/software coprocessing platform was investigated. A software based wavelet and independent component analysis (ICA) eyeblink detection and removal process was extended to enable variation in its processing parameters. Exploiting the efficiency of hardware and the reconfigurability of software, it was ported to a field programmable gate array (FPGA) development platform which was found to be capable of implementing the revised algorithm, although not in real-time. The implemented hardware and software solution was applied to a collection of both simulated and clinically acquired EEG data with known artifact and waveform characteristics to assess its speed and accuracy. Configured for optimal accuracy in terms of minimal false positives and negatives as well as maintaining the integrity of the underlying EEG, especially when encountering EEG waveform patterns with an appearance similar to eyeblink artifacts, the system was capable of processing a 10 second EEG epoch in an average of 123 seconds. Configured for efficiency, but with diminished accuracy, the system required an average of 34 seconds. Varying the ICA contrast function showed that the gaussian nonlinearity provided the best combination of reliability and accuracy, albeit with a long execution time. The cubic nonlinearity was fast, but unreliable, while the hyperbolic tangent contrast function frequently diverged. It is believed that the utilization of programmable logic with increased logic capacity and processing speed may enable this approach to achieve the objective of real-time operation

Tuning the Performance of a Computational Persistent Homology Package

In recent years, persistent homology has become an attractive method for data analysis. It captures topological features, such as connected components, holes, and voids from point cloud data and summarizes the way in which these features appear and disappear in a filtration sequence. In this project, we focus on improving the performanceof Eirene, a computational package for persistent homology. Eirene is a 5000-line open-source software library implemented in the dynamic programming language Julia. We use the Julia profiling tools to identify performance bottlenecks and develop novel methods to manage them, including the parallelization of some time-consuming functions on multicore/manycore hardware. Empirical results show that performance can be greatly improved