17,009 research outputs found

    Cloud Bioinformatics in a private cloud deployment

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    Target and (Astro-)WISE technologies - Data federations and its applications

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    After its first implementation in 2003 the Astro-WISE technology has been rolled out in several European countries and is used for the production of the KiDS survey data. In the multi-disciplinary Target initiative this technology, nicknamed WISE technology, has been further applied to a large number of projects. Here, we highlight the data handling of other astronomical applications, such as VLT-MUSE and LOFAR, together with some non-astronomical applications such as the medical projects Lifelines and GLIMPS, the MONK handwritten text recognition system, and business applications, by amongst others, the Target Holding. We describe some of the most important lessons learned and describe the application of the data-centric WISE type of approach to the Science Ground Segment of the Euclid satellite.Comment: 9 pages, 5 figures, Proceedngs IAU Symposium No 325 Astroinformatics 201

    Point-of-care testing for disasters: needs assessment, strategic planning, and future design.

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    Objective evidence-based national surveys serve as a first step in identifying suitable point-of-care device designs, effective test clusters, and environmental operating conditions. Preliminary survey results show the need for point-of-care testing (POCT) devices using test clusters that specifically detect pathogens found in disaster scenarios. Hurricane Katrina, the tsunami in southeast Asia, and the current influenza pandemic (H1N1, "swine flu") vividly illustrate lack of national and global preparedness. Gap analysis of current POCT devices versus survey results reveals how POCT needs can be fulfilled. Future thinking will help avoid the worst consequences of disasters on the horizon, such as extensively drug-resistant tuberculosis and pandemic influenzas. A global effort must be made to improve POC technologies to rapidly diagnose and treat patients to improve triaging, on-site decision making, and, ultimately, economic and medical outcomes

    The approach of Healthcare Infrastructure Public-Private Partnership (PPP) in Developing Countries: for the equal good to Korea Interest Group and the Recipient Country

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    Over the past decade, Public-Private Partnerships (PPPs) have increasingly found their application in the sector of health infrastructure. The objective of this paper is to determine whether PPPs are a viable option for health infrastructure projects in developing countries. For this purpose, the author discusses and describes PPPs in general and specifies features of PPPs, which may be relevant for the healthcare sector and developing countries. In the next step, the author analyses PPP projects that are operating and projects that the author had involved and establishes key learnings from the undertaking. The combined evidence suggests that the PPP model for health infrastructure projects in developing countries can be highly risky for the countries, but also it possesses great insecurity for the participant entities. The author concludes PPP is not a better alternative to ODA in health infrastructure development in developing countries, but it should be an option. Also, the author suggests three conditions, those are prioritizing countries to build partnerships, secure evidence of partner country’s commitment, testify project design through multiple steps for both the public and the private to successfully use PPP for better health delivery.open석

    Designing a training tool for imaging mental models

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    The training process can be conceptualized as the student acquiring an evolutionary sequence of classification-problem solving mental models. For example a physician learns (1) classification systems for patient symptoms, diagnostic procedures, diseases, and therapeutic interventions and (2) interrelationships among these classifications (e.g., how to use diagnostic procedures to collect data about a patient's symptoms in order to identify the disease so that therapeutic measures can be taken. This project developed functional specifications for a computer-based tool, Mental Link, that allows the evaluative imaging of such mental models. The fundamental design approach underlying this representational medium is traversal of virtual cognition space. Typically intangible cognitive entities and links among them are visible as a three-dimensional web that represents a knowledge structure. The tool has a high degree of flexibility and customizability to allow extension to other types of uses, such a front-end to an intelligent tutoring system, knowledge base, hypermedia system, or semantic network

    Evaluating indoor positioning systems in a shopping mall : the lessons learned from the IPIN 2018 competition

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    The Indoor Positioning and Indoor Navigation (IPIN) conference holds an annual competition in which indoor localization systems from different research groups worldwide are evaluated empirically. The objective of this competition is to establish a systematic evaluation methodology with rigorous metrics both for real-time (on-site) and post-processing (off-site) situations, in a realistic environment unfamiliar to the prototype developers. For the IPIN 2018 conference, this competition was held on September 22nd, 2018, in Atlantis, a large shopping mall in Nantes (France). Four competition tracks (two on-site and two off-site) were designed. They consisted of several 1 km routes traversing several floors of the mall. Along these paths, 180 points were topographically surveyed with a 10 cm accuracy, to serve as ground truth landmarks, combining theodolite measurements, differential global navigation satellite system (GNSS) and 3D scanner systems. 34 teams effectively competed. The accuracy score corresponds to the third quartile (75th percentile) of an error metric that combines the horizontal positioning error and the floor detection. The best results for the on-site tracks showed an accuracy score of 11.70 m (Track 1) and 5.50 m (Track 2), while the best results for the off-site tracks showed an accuracy score of 0.90 m (Track 3) and 1.30 m (Track 4). These results showed that it is possible to obtain high accuracy indoor positioning solutions in large, realistic environments using wearable light-weight sensors without deploying any beacon. This paper describes the organization work of the tracks, analyzes the methodology used to quantify the results, reviews the lessons learned from the competition and discusses its future

    Collaborative Federated Learning For Healthcare: Multi-Modal COVID-19 Diagnosis at the Edge

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    Despite significant improvements over the last few years, cloud-based healthcare applications continue to suffer from poor adoption due to their limitations in meeting stringent security, privacy, and quality of service requirements (such as low latency). The edge computing trend, along with techniques for distributed machine learning such as federated learning, have gained popularity as a viable solution in such settings. In this paper, we leverage the capabilities of edge computing in medicine by analyzing and evaluating the potential of intelligent processing of clinical visual data at the edge allowing the remote healthcare centers, lacking advanced diagnostic facilities, to benefit from the multi-modal data securely. To this aim, we utilize the emerging concept of clustered federated learning (CFL) for an automatic diagnosis of COVID-19. Such an automated system can help reduce the burden on healthcare systems across the world that has been under a lot of stress since the COVID-19 pandemic emerged in late 2019. We evaluate the performance of the proposed framework under different experimental setups on two benchmark datasets. Promising results are obtained on both datasets resulting in comparable results against the central baseline where the specialized models (i.e., each on a specific type of COVID-19 imagery) are trained with central data, and improvements of 16\% and 11\% in overall F1-Scores have been achieved over the multi-modal model trained in the conventional Federated Learning setup on X-ray and Ultrasound datasets, respectively. We also discuss in detail the associated challenges, technologies, tools, and techniques available for deploying ML at the edge in such privacy and delay-sensitive applications.Comment: preprint versio

    Outlook Magazine, Winter 2014

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    https://digitalcommons.wustl.edu/outlook/1194/thumbnail.jp
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