Class Activation Map-based Weakly supervised Hemorrhage Segmentation using Resnet-LSTM in Non-Contrast Computed Tomography images

In clinical settings, intracranial hemorrhages (ICH) are routinely diagnosed using non-contrast CT (NCCT) for severity assessment. Accurate automated segmentation of ICH lesions is the initial and essential step, immensely useful for such assessment. However, compared to other structural imaging modalities such as MRI, in NCCT images ICH appears with very low contrast and poor SNR. Over recent years, deep learning (DL)-based methods have shown great potential, however, training them requires a huge amount of manually annotated lesion-level labels, with sufficient diversity to capture the characteristics of ICH. In this work, we propose a novel weakly supervised DL method for ICH segmentation on NCCT scans, using image-level binary classification labels, which are less time-consuming and labor-efficient when compared to the manual labeling of individual ICH lesions. Our method initially determines the approximate location of ICH using class activation maps from a classification network, which is trained to learn dependencies across contiguous slices. We further refine the ICH segmentation using pseudo-ICH masks obtained in an unsupervised manner. The method is flexible and uses a computationally light architecture during testing. On evaluating our method on the validation data of the MICCAI 2022 INSTANCE challenge, our method achieves a Dice value of 0.55, comparable with those of existing weakly supervised method (Dice value of 0.47), despite training on a much smaller training data

FickleNet: Weakly and Semi-supervised Semantic Image Segmentation using Stochastic Inference

The main obstacle to weakly supervised semantic image segmentation is the difficulty of obtaining pixel-level information from coarse image-level annotations. Most methods based on image-level annotations use localization maps obtained from the classifier, but these only focus on the small discriminative parts of objects and do not capture precise boundaries. FickleNet explores diverse combinations of locations on feature maps created by generic deep neural networks. It selects hidden units randomly and then uses them to obtain activation scores for image classification. FickleNet implicitly learns the coherence of each location in the feature maps, resulting in a localization map which identifies both discriminative and other parts of objects. The ensemble effects are obtained from a single network by selecting random hidden unit pairs, which means that a variety of localization maps are generated from a single image. Our approach does not require any additional training steps and only adds a simple layer to a standard convolutional neural network; nevertheless it outperforms recent comparable techniques on the Pascal VOC 2012 benchmark in both weakly and semi-supervised settings.Comment: To appear in CVPR 201