7,978 research outputs found

    Converging organoids and extracellular matrix::New insights into liver cancer biology

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    Approximate Computing Survey, Part I: Terminology and Software & Hardware Approximation Techniques

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    The rapid growth of demanding applications in domains applying multimedia processing and machine learning has marked a new era for edge and cloud computing. These applications involve massive data and compute-intensive tasks, and thus, typical computing paradigms in embedded systems and data centers are stressed to meet the worldwide demand for high performance. Concurrently, the landscape of the semiconductor field in the last 15 years has constituted power as a first-class design concern. As a result, the community of computing systems is forced to find alternative design approaches to facilitate high-performance and/or power-efficient computing. Among the examined solutions, Approximate Computing has attracted an ever-increasing interest, with research works applying approximations across the entire traditional computing stack, i.e., at software, hardware, and architectural levels. Over the last decade, there is a plethora of approximation techniques in software (programs, frameworks, compilers, runtimes, languages), hardware (circuits, accelerators), and architectures (processors, memories). The current article is Part I of our comprehensive survey on Approximate Computing, and it reviews its motivation, terminology and principles, as well it classifies and presents the technical details of the state-of-the-art software and hardware approximation techniques.Comment: Under Review at ACM Computing Survey

    Beam scanning by liquid-crystal biasing in a modified SIW structure

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    A fixed-frequency beam-scanning 1D antenna based on Liquid Crystals (LCs) is designed for application in 2D scanning with lateral alignment. The 2D array environment imposes full decoupling of adjacent 1D antennas, which often conflicts with the LC requirement of DC biasing: the proposed design accommodates both. The LC medium is placed inside a Substrate Integrated Waveguide (SIW) modified to work as a Groove Gap Waveguide, with radiating slots etched on the upper broad wall, that radiates as a Leaky-Wave Antenna (LWA). This allows effective application of the DC bias voltage needed for tuning the LCs. At the same time, the RF field remains laterally confined, enabling the possibility to lay several antennas in parallel and achieve 2D beam scanning. The design is validated by simulation employing the actual properties of a commercial LC medium

    An empirical investigation of the relationship between integration, dynamic capabilities and performance in supply chains

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    This research aimed to develop an empirical understanding of the relationships between integration, dynamic capabilities and performance in the supply chain domain, based on which, two conceptual frameworks were constructed to advance the field. The core motivation for the research was that, at the stage of writing the thesis, the combined relationship between the three concepts had not yet been examined, although their interrelationships have been studied individually. To achieve this aim, deductive and inductive reasoning logics were utilised to guide the qualitative study, which was undertaken via multiple case studies to investigate lines of enquiry that would address the research questions formulated. This is consistent with the author’s philosophical adoption of the ontology of relativism and the epistemology of constructionism, which was considered appropriate to address the research questions. Empirical data and evidence were collected, and various triangulation techniques were employed to ensure their credibility. Some key features of grounded theory coding techniques were drawn upon for data coding and analysis, generating two levels of findings. These revealed that whilst integration and dynamic capabilities were crucial in improving performance, the performance also informed the former. This reflects a cyclical and iterative approach rather than one purely based on linearity. Adopting a holistic approach towards the relationship was key in producing complementary strategies that can deliver sustainable supply chain performance. The research makes theoretical, methodological and practical contributions to the field of supply chain management. The theoretical contribution includes the development of two emerging conceptual frameworks at the micro and macro levels. The former provides greater specificity, as it allows meta-analytic evaluation of the three concepts and their dimensions, providing a detailed insight into their correlations. The latter gives a holistic view of their relationships and how they are connected, reflecting a middle-range theory that bridges theory and practice. The methodological contribution lies in presenting models that address gaps associated with the inconsistent use of terminologies in philosophical assumptions, and lack of rigor in deploying case study research methods. In terms of its practical contribution, this research offers insights that practitioners could adopt to enhance their performance. They can do so without necessarily having to forgo certain desired outcomes using targeted integrative strategies and drawing on their dynamic capabilities

    ABC: Adaptive, Biomimetic, Configurable Robots for Smart Farms - From Cereal Phenotyping to Soft Fruit Harvesting

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    Currently, numerous factors, such as demographics, migration patterns, and economics, are leading to the critical labour shortage in low-skilled and physically demanding parts of agriculture. Thus, robotics can be developed for the agricultural sector to address these shortages. This study aims to develop an adaptive, biomimetic, and configurable modular robotics architecture that can be applied to multiple tasks (e.g., phenotyping, cutting, and picking), various crop varieties (e.g., wheat, strawberry, and tomato) and growing conditions. These robotic solutions cover the entire perception–action–decision-making loop targeting the phenotyping of cereals and harvesting fruits in a natural environment. The primary contributions of this thesis are as follows. a) A high-throughput method for imaging field-grown wheat in three dimensions, along with an accompanying unsupervised measuring method for obtaining individual wheat spike data are presented. The unsupervised method analyses the 3D point cloud of each trial plot, containing hundreds of wheat spikes, and calculates the average size of the wheat spike and total spike volume per plot. Experimental results reveal that the proposed algorithm can effectively identify spikes from wheat crops and individual spikes. b) Unlike cereal, soft fruit is typically harvested by manual selection and picking. To enable robotic harvesting, the initial perception system uses conditional generative adversarial networks to identify ripe fruits using synthetic data. To determine whether the strawberry is surrounded by obstacles, a cluster complexity-based perception system is further developed to classify the harvesting complexity of ripe strawberries. c) Once the harvest-ready fruit is localised using point cloud data generated by a stereo camera, the platform’s action system can coordinate the arm to reach/cut the stem using the passive motion paradigm framework, as inspired by studies on neural control of movement in the brain. Results from field trials for strawberry detection, reaching/cutting the stem of the fruit with a mean error of less than 3 mm, and extension to analysing complex canopy structures/bimanual coordination (searching/picking) are presented. Although this thesis focuses on strawberry harvesting, ongoing research is heading toward adapting the architecture to other crops. The agricultural food industry remains a labour-intensive sector with a low margin, and cost- and time-efficiency business model. The concepts presented herein can serve as a reference for future agricultural robots that are adaptive, biomimetic, and configurable

    Meso-scale FDM material layout design strategies under manufacturability constraints and fracture conditions

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    In the manufacturability-driven design (MDD) perspective, manufacturability of the product or system is the most important of the design requirements. In addition to being able to ensure that complex designs (e.g., topology optimization) are manufacturable with a given process or process family, MDD also helps mechanical designers to take advantage of unique process-material effects generated during manufacturing. One of the most recognizable examples of this comes from the scanning-type family of additive manufacturing (AM) processes; the most notable and familiar member of this family is the fused deposition modeling (FDM) or fused filament fabrication (FFF) process. This process works by selectively depositing uniform, approximately isotropic beads or elements of molten thermoplastic material (typically structural engineering plastics) in a series of pre-specified traces to build each layer of the part. There are many interesting 2-D and 3-D mechanical design problems that can be explored by designing the layout of these elements. The resulting structured, hierarchical material (which is both manufacturable and customized layer-by-layer within the limits of the process and material) can be defined as a manufacturing process-driven structured material (MPDSM). This dissertation explores several practical methods for designing these element layouts for 2-D and 3-D meso-scale mechanical problems, focusing ultimately on design-for-fracture. Three different fracture conditions are explored: (1) cases where a crack must be prevented or stopped, (2) cases where the crack must be encouraged or accelerated, and (3) cases where cracks must grow in a simple pre-determined pattern. Several new design tools, including a mapping method for the FDM manufacturability constraints, three major literature reviews, the collection, organization, and analysis of several large (qualitative and quantitative) multi-scale datasets on the fracture behavior of FDM-processed materials, some new experimental equipment, and the refinement of a fast and simple g-code generator based on commercially-available software, were developed and refined to support the design of MPDSMs under fracture conditions. The refined design method and rules were experimentally validated using a series of case studies (involving both design and physical testing of the designs) at the end of the dissertation. Finally, a simple design guide for practicing engineers who are not experts in advanced solid mechanics nor process-tailored materials was developed from the results of this project.U of I OnlyAuthor's request

    PARAMETRIC APPROACHES TO BALANCE STORMWATER MANAGEMENT AND HUMAN WELLBEING WITHIN URBAN GREEN SPACE

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    Through rapid urbanisation, urban green spaces (UGS) have become increasingly limited and valuable in high-density urban environments. However, meeting the diverse requirements of sustainable urban development often leads to conflicts in UGS usage. For example, the presence of stormwater treatment facilities may hinder residents' access to adjacent UGS. Traditional approaches to UGS design typically focus on separate evaluations of human wellbeing and stormwater management. However, using questionnaires, interviews, and surveys for human wellbeing evaluation can be challenging to generalise across different projects and cities. Additionally, professional hydrological models used for stormwater management require extensive knowledge of hydrology and struggle to integrate their 2D evaluation methods with 3D models. To address these challenges, this thesis proposes a novel framework to integrate the two types of analysis within a system for balancing the needs of human wellbeing and stormwater management in UGS design. The framework incorporates criteria and parameters for evaluating human wellbeing and stormwater management in a 3D model and introduces an approach to compare these two needs in terms of UGS area and suitable location. The contributions of this thesis to multi-objective UGS design are as follows: (1) defining human wellbeing evaluation through Accessibility and Usability assessment, which considers factors such as connectivity, walking distance, space enclosure, and space availability; (2) simplifying stormwater evaluation using particle systems and design curves to streamline complex hydrological models; (3) integrating the two evaluations by comparing their quantified requirements for UGS area and location; and (4) incorporating parameters to provide flexibility and accommodate various design scenarios and objectives. The advantages of this evaluation framework are demonstrated through two case studies: (1) the human wellbeing analysis based on spatial parameters in the framework shows sensitivity to site variations, including UGS quantity and distribution, population density, terrain, road context, height of void space, and more; (2) the simplified stormwater analysis effectively captures site variations represented by UGS quantity and distribution, building distribution, as well as terrain, providing recommendations for each UGS with different types and sizes of stormwater facilities. (3) With the features of spatial parameter evaluation, the framework is feasible to adjust relevant thresholds and include more parameters to respond to specific project needs. (4) By quantifying the two different requirements for UGS and comparing them, any UGS with high usage conflicts can be easily identified. By evaluating all proposed criteria for UGSs in the 3D model, designers can conveniently observe simulation and adjust design scenarios to address identified usage conflicts. Thus, the proposed evaluation framework in this thesis would be valuable in effectively supporting further multi-objective UGS design

    Using Crowd-Based Software Repositories to Better Understand Developer-User Interactions

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    Software development is a complex process. To serve the final software product to the end user, developers need to rely on a variety of software artifacts throughout the development process. The term software repository used to denote only containers of source code such as version control systems; more recent usage has generalized the concept to include a plethora of software development artifact kinds and their related meta-data. Broadly speaking, software repositories include version control systems, technical documentation, issue trackers, question and answer sites, distribution information, etc. The software repositories can be based on a specific project (e.g., bug tracker for Firefox), or be crowd-sourced (e.g., questions and answers on technical Q&A websites). Crowd-based software artifacts are created as by-products of developer-user interactions which are sometimes referred to as communication channels. In this thesis, we investigate three distinct crowd-based software repositories that follow different models of developer-user interactions. We believe through a better understanding of the crowd-based software repositories, we can identify challenges in software development and provide insights to improve the software development process. In our first study, we investigate Stack Overflow. It is the largest collection of programming related questions and answers. On Stack Overflow, developers interact with other developers to create crowd-sourced knowledge in the form of questions and answers. The results of the interactions (i.e., the question threads) become valuable information to the entire developer community. Prior research on Stack Overflow tacitly assume that questions receives answers directly on the platform and no need of interaction is required during the process. Meanwhile, the platform allows attaching comments to questions which forms discussions of the question. Our study found that question discussions occur for 59.2% of questions on Stack Overflow. For discussed and solved questions on Stack Overflow, 80.6% of the questions have the discussion begin before the accepted answer is submitted. The results of our study show the importance and nuances of interactions in technical Q&A. We then study dotfiles, a set of publicly shared user-specific configuration files for software tools. There is a culture of sharing dotfiles within the developer community, where the idea is to learn from other developers’ dotfiles and share your variants. The interaction of dotfiles sharing can be viewed as developers sources information from other developers, adapt the information to their own needs, and share their adaptations back to the community. Our study on dotfiles suggests that is a common practice among developers to share dotfiles where 25.8% of the most stared users on GitHub have a dotfiles repository. We provide a taxonomy of the commonly tracked dotfiles and a qualitative study on the commits in dotfiles repositories. We also leveraged the state-of-the-art time-series clustering technique (K-shape) to identify code churn pattern for dotfile edits. This study is the first step towards understanding the practices of maintaining and sharing dotfiles. Finally, we study app stores, the platforms that distribute software products and contain many non-technical attributes (e.g., ratings and reviews) of software products. Three major stakeholders interacts with each other in app stores: the app store owner who governs the operation of the app store; developers who publish applications on the app store; and users who browse and download applications in the app store. App stores often provide means of interaction between all three actors (e.g., app reviews, store policy) and sometimes interactions with in the same actor (e.g., developer forum). We surveyed existing app stores to extract key features from app store operation. We then labeled a representative set of app store collected by web queries. K-means is applied to the labeled app stores to detect natural groupings of app stores. We observed a diverse set of app stores through the process. Instead of a single model that describes all app stores, fundamentally, our observations show that app stores operates differently. This study provide insights in understanding how app stores can affect software development. In summary, we investigated software repositories containing software artifacts created from different developer-user interactions. These software repositories are essential for software development in providing referencing information (i.e., Stack Overflow), improving development productivity (i.e., dotfiles), and help distributing the software products to end users (i.e., app stores)

    Ideas Explosion! How Church Can Create More Ideas

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    In this project, I am addressing my NPO: A healthy church nurtures a culture of humble exploration and responsive innovation. One of the key findings is that there is not enough material focused on how a healthy church can process and explore ideas. In addition, church leaders often feel ill-equipped for a process that requires creativity. Believing that God made everyone creative, especially the church, this project is a book that details a system to explore ideas, properly discern strengths and weaknesses, and prepare leaders to make informed decisions. I created the Gather-Discern-Decide (GDD) Process from research findings, personal experiences, and feedback to guide ideation for churches. The project targets pastors and church leaders with 400 or fewer members in congregationally led systems. The book currently contains six chapters plus an introduction and a conclusion. Part 1 (chapters 1 and 2) of the book seeks to establish humanity’s partnership with God in the works of creation. It includes four values that a healthy ideation process reinforces in a congregation. Part 2 (chapters 3-6) details the GDD Process and its ability to leverage low-risk creative endeavors into larger, risky church goals. The GDD Process helps build a culture of humble exploration and responsive innovation
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