DNA Movies and Panspermia

There are several ways that our species might try to send a message to another species separated from us by space and/or time. Synthetic biology might be used to write an epitaph to our species, or simply “Kilroy was here”, in the genome of a bacterium via the patterns of either (1) the codons to exploit Life's non-equilibrium character or (2) the bases themselves to exploit Life's quasi-equilibrium character. We suggest here how DNA movies might be designed using such patterns. We also suggest that a search for mechanisms to create and preserve such patterns might lead to a better understanding of modern cells. Finally, we argue that the cutting-edge microbiology and synthetic biology needed for the Kilroy project would put origin-of-life studies in the vanguard of research

The People in Slanguage

Long before Elijah McCoy invented the lubricating device which gave us the expression the real McCoy, long before Kilroy was here, names crept into common speech and formed an interesting aspect of slang. How many of the following catch phrases, all containing names, can you explain? What do people mean when they say these

A sensitive genetic-based detection capability for Didymosphenia geminata

It is now well recognized that the increase in global transportation over the last two decades has brought with it an increased potential for the introduction of unwanted microorganisms (aquatic or terrestrial) that may have drastic effects on human and ecosystem health and agriculture. We have developed and validated a unique genetic fingerprinting tool for D. geminata. In concert, we developed field collection and preservation techniques specific for D. geminata along with genetic-based procedures that can now reliably detect D. geminate from a complex environmental community with a high degree of sensitivity. Recent work (Phase 2) has shown that the described methods will provide detection levels from <1 – 10,000 cells ml-1. We contend that the genetic based detection approaches used in this study offer great promise to meet the increasing demands to monitor the global threat from invasive micro-organisms

Disarmament, demobilisation and reintegration (DDR) as a participatory process: involving communities and beneficiaries in post-conflict disarmament programmes

Disarmament, Demobilisation and Reintegration (DDR) programmes are a structured approach to returning soldiers and militia members to civilian life. One of the aims is to support implementation of the peace process, by addressing their interests and reducing the chance of them becoming “spoilers”. Since the early 90s, DDR has been implemented in countries emerging from conflict, such as Sierra Leone, Liberia, Angola and Afghanistan. They are now underway in the Democratic Republic of Congo and Sudan. The results have been mixed, and the agencies responsible for designing and implementing DDR are still developing best practice. This study aims to identify the role of a participatory approach as a factor in ensuring success in a DDR programme. Ex-combatants, receiving communities, local implementing partners, and newlyestablished national structures can all be involved to a greater or lesser degree in the process. The argument for greater involvement – a participatory approach – includes better outcomes in terms of ownership of the process and political will, improved likelihood that real needs are addressed, greater relevance for female ex-combatants and children, sustainability in reintegration and economic initiatives, and capacity building

Doomed to failure? UKIP and the organisational challenges facing right-wing populist anti-political establishment parties

Using the UK Independence Party, we examine the effects of sudden electoral success on an Anti-Political Establishment (APE) party. The pressures of aspiring to government necessitate organisational structures resembling those of mainstream parties, while this aspiration challenges APE parties because they differ not just in terms of their policy profiles, but also in their more ‘unorthodox’ organisational make-up, inextricably linked to their electoral appeal. Robert Kilroy-Silk wanted to emphasise office-seeking goals while most members wanted the party to remain true to its APE status and not sacrifice its populist nature. This inevitably resulted in internal party conflict

From conflict to ownership: Participatory approaches to the re-integration of ex-combatants in Sierra Leone

The demobilisation and re-integration of ex-combatants has become an important element in peace-building. The need for a more holistic, integrated approach, in which there is greater local ownership of the process, has long been recognised. However, putting this into practice remains a challenge. Re-integration ultimately takes place in the community, merging with development and post-conflict reconstruction. This study of re-integration in Sierra Leone uses the concept of ‘participation’ from development discourse, meaning the extent to which potential stakeholders have a say in how interventions are designed and implemented. It finds that participation and ownership are only seen to a limited extent, and only in certain situations.Many of the ex-combatants who participated in this study felt they did not receive adequate or accurate information regarding the re-integration process. This undermines the contribution that re-integration can have to the peace-building project. Participation proves to be a useful framework for assessing re-integration programmes, and for planning the more integrated approach that has long been advocated