872 research outputs found

    Crises and collective socio-economic phenomena: simple models and challenges

    Full text link
    Financial and economic history is strewn with bubbles and crashes, booms and busts, crises and upheavals of all sorts. Understanding the origin of these events is arguably one of the most important problems in economic theory. In this paper, we review recent efforts to include heterogeneities and interactions in models of decision. We argue that the Random Field Ising model (RFIM) indeed provides a unifying framework to account for many collective socio-economic phenomena that lead to sudden ruptures and crises. We discuss different models that can capture potentially destabilising self-referential feedback loops, induced either by herding, i.e. reference to peers, or trending, i.e. reference to the past, and account for some of the phenomenology missing in the standard models. We discuss some empirically testable predictions of these models, for example robust signatures of RFIM-like herding effects, or the logarithmic decay of spatial correlations of voting patterns. One of the most striking result, inspired by statistical physics methods, is that Adam Smith's invisible hand can badly fail at solving simple coordination problems. We also insist on the issue of time-scales, that can be extremely long in some cases, and prevent socially optimal equilibria to be reached. As a theoretical challenge, the study of so-called "detailed-balance" violating decision rules is needed to decide whether conclusions based on current models (that all assume detailed-balance) are indeed robust and generic.Comment: Review paper accepted for a special issue of J Stat Phys; several minor improvements along reviewers' comment

    Dynamics of Macrosystems; Proceedings of a Workshop, September 3-7, 1984

    Get PDF
    There is an increasing awareness of the important and persuasive role that instability and random, chaotic motion play in the dynamics of macrosystems. Further research in the field should aim at providing useful tools, and therefore the motivation should come from important questions arising in specific macrosystems. Such systems include biochemical networks, genetic mechanisms, biological communities, neutral networks, cognitive processes and economic structures. This list may seem heterogeneous, but there are similarities between evolution in the different fields. It is not surprising that mathematical methods devised in one field can also be used to describe the dynamics of another. IIASA is attempting to make progress in this direction. With this aim in view this workshop was held at Laxenburg over the period 3-7 September 1984. These Proceedings cover a broad canvas, ranging from specific biological and economic problems to general aspects of dynamical systems and evolutionary theory

    Rational Decisions and Regulation of Union Entry

    Get PDF

    Parallel Architectures for Planetary Exploration Requirements (PAPER)

    Get PDF
    The Parallel Architectures for Planetary Exploration Requirements (PAPER) project is essentially research oriented towards technology insertion issues for NASA's unmanned planetary probes. It was initiated to complement and augment the long-term efforts for space exploration with particular reference to NASA/LaRC's (NASA Langley Research Center) research needs for planetary exploration missions of the mid and late 1990s. The requirements for space missions as given in the somewhat dated Advanced Information Processing Systems (AIPS) requirements document are contrasted with the new requirements from JPL/Caltech involving sensor data capture and scene analysis. It is shown that more stringent requirements have arisen as a result of technological advancements. Two possible architectures, the AIPS Proof of Concept (POC) configuration and the MAX Fault-tolerant dataflow multiprocessor, were evaluated. The main observation was that the AIPS design is biased towards fault tolerance and may not be an ideal architecture for planetary and deep space probes due to high cost and complexity. The MAX concepts appears to be a promising candidate, except that more detailed information is required. The feasibility for adding neural computation capability to this architecture needs to be studied. Key impact issues for architectural design of computing systems meant for planetary missions were also identified

    Toward a formal theory for computing machines made out of whatever physics offers: extended version

    Full text link
    Approaching limitations of digital computing technologies have spurred research in neuromorphic and other unconventional approaches to computing. Here we argue that if we want to systematically engineer computing systems that are based on unconventional physical effects, we need guidance from a formal theory that is different from the symbolic-algorithmic theory of today's computer science textbooks. We propose a general strategy for developing such a theory, and within that general view, a specific approach that we call "fluent computing". In contrast to Turing, who modeled computing processes from a top-down perspective as symbolic reasoning, we adopt the scientific paradigm of physics and model physical computing systems bottom-up by formalizing what can ultimately be measured in any physical substrate. This leads to an understanding of computing as the structuring of processes, while classical models of computing systems describe the processing of structures.Comment: 76 pages. This is an extended version of a perspective article with the same title that will appear in Nature Communications soon after this manuscript goes public on arxi

    Multiscale Modeling of Bacterial Chemotaxis

    Get PDF
    One of the central questions of modern systems biology is the role of microscopic parameters of a single cell in the behavior of a cell population. Multiscale models help to address this problem, allowing to understand population behavior from the information about single-cell molecular components and reactions. This goal requires models that are sufficiently detailed to capture central intracellular processes, but at the same time enable simulation of entire cell populations. In this work a novel multiscale (hybrid) model is presented, which describes chemotactic Escherichia coli bacterium by a combination of heterogeneous mathematical approaches in one platform: rapid-equilibrium (algebraic) models, ordinary differential equations, and stochastic processes. The multiscale approach is based on time-scale separation of key reactions. The resulting model of chemotactic bacterium describes signal processing by mixed chemoreceptor clusters (MWC model), adaptation through methylation, running and tumbling of a cell with several flagellar motors. The model is implemented in a program RapidCell. It outperforms the present simulation software in reproducing the experimental data on pathway sensitivity, and simulates bacterial populations in a computationally efficient way. The model was used to investigate chemotaxis in different gradients. A theoretical analysis of the receptor cluster (MWC) model suggested a new, constant-activity type of gradient to systematically study chemotactic behavior of bacteria in silico. Using the unique properties of this gradient, it is shown that the optimal chemotaxis is observed in a narrow range of CheA kinase activity, where concentration of the response regulator CheYp falls into the operating range of flagellar motors. Simulations further confirm that the CheB phosphorylation feedback improves chemotactic efficiency in a number of gradients by shifting the average CheYp concentration to fit the motor operating range. Comparative simulations of motility in liquid and porous media suggest that adaptation time required for optimal chemotaxis depends on the medium. In liquid medium, the variability in adaptation times among cells may be evolutionary favourable to ensure co-existence of subpopulations that will be optimally tactic in different gradients. However, in a porous medium (agar) such variability appears to be less important, because agar structure poses mainly negative selection, against subpopulations with low levels of adaptation enzymes. A detailed model of cell motion predicts existence of an additional mechanism of gradient navigation in E. coli. Based on the experimentally observed dependence of cell tumbling angle on the number of clockwise-rotating motors, the model suggests that not only the tumbling frequency, but also the angle of reorientation during a tumble depends on the swimming direction along the gradient. Although the difference in mean tumbling angles up and down the gradient predicted by the model is small, it results in a dramatic enhancement of the cellular drift velocity along the gradient. This result demonstrates a new level of optimization in E. coli chemotaxis, which arises from collective switching of several flagellar motors and a resulting fine tuning of tumbling angle. Similar strategy is likely to be used by other peritrichously flagellated bacteria, and indicates a yet another level of evolutionary optimization in bacterial chemotaxis. Concluding, multiscale models as the one presented here can be an important research instrument for understanding the cell behavior. They reflect the most important experimental knowledge about the biological system, and allow to carry out computational experiments of high complexity, which may be too complicated for experimental trials. Currently, there is abundant experimental data on signal transduction in living organisms, but there is no general mathematical framework to integrate heterogeneous models over the wide range of scales present in most biological systems. This thesis is a new stone in the work aimed to "bridge the scales" in biology
    • …
    corecore