180,327 research outputs found

    Exploring the interactions underlying flow states: A connecting analysis of flow occurrence in European Tour golfers

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    Objectives: Research to date has identified a range of factors suggested to facilitate flow states in sport. However, less attention has focused on how exactly those facilitating factors influence the occurrence of flow. Therefore, this study aimed to explore the specific ways in which such facilitators influenced flow occurrence in European Tour golfers. Design: Qualitative design. Method: Ten full-time golfers from the European Tour (M age=37; SD=13.08) participated in semi-structured interviews investigating the occurrence of their flow states. Data were interpreted using an iterative process of thematic and connecting analyses. Results: Ten facilitators of flow were identified, of which commitment and the caddie have not been reported previously. Twenty four connecting links were identified in the data, through which the caddie, effective preparation, and high-quality performance appeared to be most influential for flow occurrence. Confidence and concentration also emerged as key constructs underlying the flow experience in this setting. Conclusion: A central contribution of this study is the identification of ways in which facilitating factors could influence flow occurrence in elite golf. This process adds detail to understanding of flow occurrence, and moves beyond simply identifying factors which are associated with the experience. As such, connecting analysis is proposed as an additional strategy for qualitatively investigating flow occurrence in sport. Results are discussed in relation to previous literature, and recommendations are identified for researchers, athletes, coaches and practitioners

    Uncertainty propagation and speculation in projective forecasts of environmental change: a lake-eutrophication example

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    The issue of whether models developed for current conditions can yield correct predictions when used under changed control, as is often the case in environmental management, is discussed. Two models of different complexity are compared on the basis of performance criteria, but it appears that good performance at the calibration stage does not guarantee correctly predicted behavior. A requirement for the detection of such a failure of the model is that the prediction uncertainty range is known. Two techniques to calculate uncertainty propagation are presented and compared: a stochastic first-order error propagation based on the extended Kalman filter (EKF), and a newly developed and robust Monte Carlo set-membership procedure (MCSM). The procedures are applied to a case study of water quality, generating a projective forecast of the algal dynamics in a lake (Lake Veluwe) in response to management actions that force the system into a different mode of behavior. It is found that the forecast from the more complex model falls within the prediction uncertainty range, but its informative value is low due to large uncertainty bounds. As a substitute for time-consuming revisions of the model, educated speculation about parameter shifts is offered as an alternative approach to account for expected but unmodelled changes in the system

    Urinary chitinase 3-like protein 1 for early diagnosis of acute kidney injury : a prospective cohort study in adult critically ill patients

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    Background: Acute kidney injury (AKI) occurs frequently and adversely affects patient and kidney outcomes, especially when its severity increases from stage 1 to stages 2 or 3. Early interventions may counteract such deterioration, but this requires early detection. Our aim was to evaluate whether the novel renal damage biomarker urinary chitinase 3-like protein 1 (UCHI3L1) can detect AKI stage >= 2 more early than serum creatinine and urine output, using the respective Kidney Disease vertical bar Improving Global Outcomes (KDIGO) criteria for definition and classification of AKI, and compare this to urinary neutrophil gelatinase-associated lipocalin (UNGAL). Methods: This was a translational single-center, prospective cohort study at the 22-bed surgical and 14-bed medical intensive care units (ICU) of Ghent University Hospital. We enrolled 181 severely ill adult patients who did not yet have AKI stage >= 2 based on the KDIGO criteria at time of enrollment. The concentration of creatinine (serum, urine) and CHI3L1 (serum, urine) was measured at least daily, and urine output hourly, in the period from enrollment till ICU discharge with a maximum of 7 ICU-days. The concentration of UNGAL was measured at enrollment. The primary endpoint was the development of AKI stage >= 2 within 12 h after enrollment. Results: After enrollment, 21 (12 %) patients developed AKI stage >= 2 within the next 7 days, with 6 (3 %) of them reaching this condition within the first 12 h. The enrollment concentration of UCHI3L1 predicted the occurrence of AKI stage >= 2 within the next 12 h with a good AUC-ROC of 0.792 (95 % CI: 0.726-0.849). This performance was similar to that of UNGAL (AUC-ROC of 0.748 (95 % CI: 0.678-0.810)). Also, the samples collected in the 24-h time frame preceding diagnosis of the 1st episode of AKI stage >= 2 had a 2.0 times higher (95 % CI: 1.3-3.1) estimated marginal mean of UCHI3L1 than controls. We further found that increasing UCHI3L1 concentrations were associated with increasing AKI severity. Conclusions: In this pilot study we found that UCHI3L1 was a good biomarker for prediction of AKI stage >= 2 in adult ICU patients

    Assessing the performance of social spending in Europe

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    Based on the construction of a new composite index to assess the relative performance of welfare policies, we show that the variability of performances cannot be explained only by the amount of resources devoted to social policies, but also by its composition: countries with higher shares of social public expenditure, specifically aimed at reducing income concentration, obtain better results. This associates the traditional classification of the welfare systems to the performance obtained in the social sector

    Adherence to antiretroviral therapy assessed by drug level monitoring and self-report in cameroon

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    OBJECTIVES: To compare adherence to antiretroviral therapy using drug level monitoring and self-report and to explore the relation between these 2 methods and viral load measurements. METHODS: Sixty patients received a fixed-dose combination of nevirapine, stavudine, and lamivudine in a clinical study in Cameroon. Adherence was assessed every 6 months until month 36 by nevirapine minimal plasma concentration and self-report. Plasma HIV-1 viral load was determined at the same time. Analyses included 159 complete observations. RESULTS: The proportion of patients labeled as "adherent" was significantly lower using nevirapine monitoring (88.7%, 95% confidence interval [CI]: 82.7 to 93.2) than self-report (97.5%, CI: 93.7 to 99.3; P = 0.002). Virologic failure was associated with the nevirapine concentration (adjusted odds ratio [aOR] = 4.43; P = 0.018) but not with the self-reported adherence (aOR = 0.84; P = 0.9). As compared with the virologic outcome, the sensitivity of nevirapine level monitoring for predicting inadequate adherence was 20.5%, the specificity was 91.7%, the positive predictive value was 44.4%, and the negative predictive value was 78.0%. For self-report, the respective values were 2.6%, 97.5%, 25.0%, and 75.5%. CONCLUSIONS: Drug level monitoring provided a more reliable estimate of adherence than self-report. This method could be used in research settings. Operational research is required to define how to improve the accuracy of the self-report method because it is the most feasible method in clinical practice

    Haematological Performances of Jaundice Catfish (Clarias gariepinus, Burch)

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    The research was aimed to study hematological performances of jaundice and healthy catfish (Clarias gariepinus, Burch.). Fifty fish (i.e. twenty five of jaundice and twenty five of healthy catfish) were collected and analyzed for their hematological parameters. The blood samples were taken from caudal vein of the fish by using 2.5 ml-spuit, and then were collected into bottle samples with no or containing anticoagulant of 1% EDTA. Blood samples in the bottles with anticoagulant were used for blood cell counting and blood glucose analysis. Total billirubin, direct and indirect billirubin, and transaminase-enzymes were measured from serum of the blood samples without anticoagulant. Results showed that the blood cells (i.e. leucocytes, erythrocytes, hemoglobin, and haematocrit) of the jaundice catfish were lower than the healthy catfish. On the other hand, the blood glucose concentration) of the jaundice fish was higher. The direct and indirect billirubin concentration of the jaundice catfish was also higher, which indicated that the jaundice catfish was hiperbillirubin. However, both jaundice and heathty catfish performed high concentration of the transaminase enzymes in their blood serum. It was suggested that the hiperbillirubin-jaundice fish was mal function of their hepar and showing a stress symptoms. Keywords: Billirubin, Blood glucose, Clarias gariepinus, Hematology, Jaundice catfish, Transaminase enzym

    Experimental Modeling of NOx and PM Generation from Combustion of Various Biodiesel Blends for Urban Transport Buses

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    Biodiesel has diverse sources of feedstock and the amount and composition of its emissions vary significantly depending on combustion conditions. Results of laboratory and field tests reveal that nitrogen oxides (NOx) and particulate matter (PM) emissions from biodiesel are influenced more by combustion conditions than emissions from regular diesel. Therefore, NOx and PM emissions documented through experiments and modeling studies are the primary focus of this investigation. In addition, a comprehensive analysis of the feedstock-related combustion characteristics and pollutants are investigated. Research findings verify that the oxygen contents, the degree of unsaturation, and the size of the fatty acids in biodiesel are the most important factors that determine the amounts and compositions of NOx and PM emissions
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