23,149 research outputs found
DeepCare: A Deep Dynamic Memory Model for Predictive Medicine
Personalized predictive medicine necessitates the modeling of patient illness
and care processes, which inherently have long-term temporal dependencies.
Healthcare observations, recorded in electronic medical records, are episodic
and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural
network that reads medical records, stores previous illness history, infers
current illness states and predicts future medical outcomes. At the data level,
DeepCare represents care episodes as vectors in space, models patient health
state trajectories through explicit memory of historical records. Built on Long
Short-Term Memory (LSTM), DeepCare introduces time parameterizations to handle
irregular timed events by moderating the forgetting and consolidation of memory
cells. DeepCare also incorporates medical interventions that change the course
of illness and shape future medical risk. Moving up to the health state level,
historical and present health states are then aggregated through multiscale
temporal pooling, before passing through a neural network that estimates future
outcomes. We demonstrate the efficacy of DeepCare for disease progression
modeling, intervention recommendation, and future risk prediction. On two
important cohorts with heavy social and economic burden -- diabetes and mental
health -- the results show improved modeling and risk prediction accuracy.Comment: Accepted at JBI under the new name: "Predicting healthcare
trajectories from medical records: A deep learning approach
Ensemble Joint Sparse Low Rank Matrix Decomposition for Thermography Diagnosis System
Composite is widely used in the aircraft industry and it is essential for manufacturers to monitor its health and quality. The most commonly found defects of composite are debonds and delamination. Different inner defects with complex irregular shape is difficult to be diagnosed by using conventional thermal imaging methods. In this paper, an ensemble joint sparse low rank matrix decomposition (EJSLRMD) algorithm is proposed by applying the optical pulse thermography (OPT) diagnosis system. The proposed algorithm jointly models the low rank and sparse pattern by using concatenated feature space. In particular, the weak defects information can be separated from strong noise and the resolution contrast of the defects has significantly been improved. Ensemble iterative sparse modelling are conducted to further enhance the weak information as well as reducing the computational cost. In order to show the robustness and efficacy of the model, experiments are conducted to detect the inner debond on multiple carbon fiber reinforced polymer (CFRP) composites. A comparative analysis is presented with general OPT algorithms. Not withstand above, the proposed model has been evaluated on synthetic data and compared with other low rank and sparse matrix decomposition algorithms
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