6,255 research outputs found
Schizophrenia – time to commit to policy change
Schizophrenia is recognised as one of the most complex and profound mental health conditions, steeped in both myth and reality. Efforts needs to be multifaceted, including policy development, treatment guidance and scientific innovation, with all stakeholders working together to ensure meaningful progress. This report delves into the unique needs of people with schizophrenia, exploring supportive measures for their well-being, practical and attainable recommendations for change. The message to all nations, policy makers, payers and healthcare professionals is clear: strive for excellence, but most importantly – start somewhere
A Spark Of Emotion: The Impact of Electrical Facial Muscle Activation on Emotional State and Affective Processing
Facial feedback, which involves the brain receiving information about the activation of facial muscles, has the potential to influence our emotional states and judgments. The extent to which this applies is still a matter of debate, particularly considering a failed replication of a seminal study. One factor contributing to the lack of replication in facial feedback effects may be the imprecise manipulation of facial muscle activity in terms of both degree and timing. To overcome these limitations, this thesis proposes a non-invasive method for inducing precise facial muscle contractions, called facial neuromuscular electrical stimulation (fNMES). I begin by presenting a systematic literature review that lays the groundwork for standardising the use of fNMES in psychological research, by evaluating its application in existing studies. This review highlights two issues, the lack of use of fNMES in psychology research and the lack of parameter reporting. I provide practical recommendations for researchers interested in implementing fNMES. Subsequently, I conducted an online experiment to investigate participants' willingness to participate in fNMES research. This experiment revealed that concerns over potential burns and involuntary muscle movements are significant deterrents to participation. Understanding these anxieties is critical for participant management and expectation setting. Subsequently, two laboratory studies are presented that investigated the facial FFH using fNMES. The first study showed that feelings of happiness and sadness, and changes in peripheral physiology, can be induced by stimulating corresponding facial muscles with 5–seconds of fNMES. The second experiment showed that fNMES-induced smiling alters the perception of ambiguous facial emotions, creating a bias towards happiness, and alters neural correlates of face processing, as measured with event-related potentials (ERPs). In summary, the thesis presents promising results for testing the facial feedback hypothesis with fNMES and provides practical guidelines and recommendations for researchers interested in using fNMES for psychological research
Know Thyself: Improving Interoceptive Ability Through Ambient Biofeedback in the Workplace
Interoception, the perception of the body’s internal state, is intimately connected to self-regulation and wellbeing. Grounded in the affective science literature, we design an ambient biofeedback system called Soni-Phy and a lab study to investigate whether, when and how an unobtrusive biofeedback system can be used to improve interoceptive sensibility and accuracy by amplifying a users’ internal state. This research has practical significance for the design and improvement of assistive technologies for the workplace
Life on a scale:Deep brain stimulation in anorexia nervosa
Anorexia nervosa (AN) is a severe psychiatric disorder marked by low body weight, body image abnormalities, and anxiety and shows elevated rates of morbidity, comorbidity and mortality. Given the limited availability of evidence-based treatments, there is an urgent need to investigate new therapeutic options that are informed by the disorder’s underlying neurobiological mechanisms. This thesis represents the first study in the Netherlands and one of a limited number globally to evaluate the efficacy, safety, and tolerability of deep brain stimulation (DBS) in the treatment of AN. DBS has the advantage of being both reversible and adjustable. Beyond assessing the primary impact of DBS on body weight, psychological parameters, and quality of life, this research is novel in its comprehensive approach. We integrated evaluations of efficacy with critical examinations of the functional impact of DBS in AN, including fMRI, electroencephalography EEG, as well as endocrinological and metabolic assessments. Furthermore, this work situates AN within a broader theoretical framework, specifically focusing on its manifestation as a form of self-destructive behavior. Finally, we reflect on the practical, ethical and philosophical aspects of conducting an experimental, invasive procedure in a vulnerable patient group. This thesis deepens our understanding of the neurobiological underpinnings of AN and paves the way for future research and potential clinical applications of DBS in the management of severe and enduring AN
Cognitive Inhibition as a Core Component of Executive Functions:Exploring Intra- and Interindividual Differences
Cognitive inhibition is an essential executive function that we use in our everyday lives. Numerous factors have been claimed to influence this construct including video gaming, exercise and expertise in musical instruments. However, in this thesis, I focus on an understudied factor, the alignment of chronotype and testing time, and a heavily studied yet controversial factor, bilingualism. Throughout this thesis, with one exception, I present a series of experiments which have been conducted online. In the first empirical chapter, I examined a relatively novel Faces task which the authors have claimed to measure three cognitive processes, including two different forms of inhibition and task switching (Chapter 2). Based on this chapter's findings, I decided to use the Faces task in Chapters 3, 4 and 6. The next two chapters determined whether the alignment of time of testing and chronotype influences inhibition and task switching among the young adult (Chapter 3) and older adult (Chapter 4) population. Afterwards, I explored how conflict is resolved through a mouse tracking paradigm and by extension, whether this paradigm can be used for a variety of inhibition tasks (Chapter 5). For the final empirical chapter, I identified whether training inhibition in a verbal domain impacts inhibition in a non-verbal domain (i.e., far transfer effects). To achieve this, I investigated whether bilingualism, which can be seen as a form of cognitive training within the verbal domain, influences performance in non-verbal tasks which index inhibition (Chapter 6). The main findings of this thesis suggest that cognitive inhibition is not substantially impacted by synchrony effects nor by bilingualism. Furthermore, the findings imply that mouse tracking could be a promising tool to use to examine cognitive inhibition
Social decision-making in highly psychopathic offenders – A systematic literature review
Despite their decisions to frequently manipulate or even callously harm others in real life, highly psychopathic individuals often exhibit judgments comparable to individuals low in psychopathy when examined experimentally. This conundrum has generated a rich body of studies exploring social decision-making in psychopathy, but no systematic review to date has identified decision-making as measured in real-world or simulated social interactions in criminal offender samples assessed for psychopathic traits. Out of 807 studies provided by database searching in August 2022, 16 studies were included in this review and revealed behavioral economic games and paradigms for the assessment of aggressive behavior as the two main approaches to dissect social decision-making in offender samples regarding psychopathy. The specific paradigms exposed the multidimensional structure of both, the psychopathy construct and social decision-making. On one side, the distinct affordances of the social tasks, such as trust, power, or reactions to unfairness and provocation shed light on the inconsistent relations of decisions in experimental situations and psychopathy. On the other side, studies analyzing decision outcomes with respect to the distinct psychopathy subcomponents revealed nuanced interference effects with the social decision tasks. The review encourages a differentiated perspective to the psychopathy construct and social decision-making processes alike
Conversations on Empathy
In the aftermath of a global pandemic, amidst new and ongoing wars, genocide, inequality, and staggering ecological collapse, some in the public and political arena have argued that we are in desperate need of greater empathy — be this with our neighbours, refugees, war victims, the vulnerable or disappearing animal and plant species. This interdisciplinary volume asks the crucial questions: How does a better understanding of empathy contribute, if at all, to our understanding of others? How is it implicated in the ways we perceive, understand and constitute others as subjects? Conversations on Empathy examines how empathy might be enacted and experienced either as a way to highlight forms of otherness or, instead, to overcome what might otherwise appear to be irreducible differences. It explores the ways in which empathy enables us to understand, imagine and create sameness and otherness in our everyday intersubjective encounters focusing on a varied range of "radical others" – others who are perceived as being dramatically different from oneself. With a focus on the importance of empathy to understand difference, the book contends that the role of empathy is critical, now more than ever, for thinking about local and global challenges of interconnectedness, care and justice
Differences in well-being:the biological and environmental causes, related phenotypes, and real-time assessment
Well-being is a complex, and multifaceted construct that includes feeling good and functioning well. There is a growing global recognition of well-being as an important research topic and public policy goal. Well-being is related to less behavioral and emotional problems, and is associated with many positive aspects of daily life, including longevity, higher educational achievement, happier marriage, and more productivity at work. People differ in their levels of well-being, i.e., some people are in general happier or more satisfied with their lives than others. These individual differences in well-being can arise from many different factors, including biological (genetic) influences and environmental influences. To enhance the development of future mental health prevention and intervention strategies to increase well-being, more knowledge about these determinants and factors underlying well-being is needed. In this dissertation, I aimed to increase the understanding of the etiology in a series of studies using different methods, including systematic reviews, meta-analyses, twin designs, and molecular genetic designs. In part I, we brought together all published studies on the neural and physiological factors underlying well-being. This overview allowed us to critically investigate the claims made about the biology involved in well-being. The number of studies on the neural and physiological factors underlying well-being is increasing and the results point towards potential correlates of well-being. However, samples are often still small, and studies focus mostly on a single biomarker. Therefore, more well-powered, data-driven, and integrative studies across biological categories are needed to better understand the neural and physiological pathways that play a role in well-being. In part II, we investigated the overlap between well-being and a range of other phenotypes to learn more about the etiology of well-being. We report a large overlap with phenotypes including optimism, resilience, and depressive symptoms. Furthermore, when removing the genetic overlap between well-being and depressive symptoms, we showed that well-being has unique genetic associations with a range of phenotypes, independently from depressive symptoms. These results can be helpful in designing more effective interventions to increase well-being, taking into account the overlap and possible causality with other phenotypes. In part III, we used the extreme environmental change during the COVID-19 pandemic to investigate individual differences in the effects of such environmental changes on well-being. On average, we found a negative effect of the pandemic on different aspects of well-being, especially further into the pandemic. Whereas most previous studies only looked at this average negative effect of the pandemic on well-being, we focused on the individual differences as well. We reported large individual differences in the effects of the pandemic on well-being in both chapters. This indicates that one-size-fits-all preventions or interventions to maintain or increase well-being during the pandemic or lockdowns will not be successful for the whole population. Further research is needed for the identification of protective factors and resilience mechanisms to prevent further inequality during extreme environmental situations. In part IV, we looked at the real-time assessment of well-being, investigating the feasibility and results of previous studies. The real-time assessment of well-being, related variables, and the environment can lead to new insights about well-being, i.e., results that we cannot capture with traditional survey research. The real-time assessment of well-being is therefore a promising area for future research to unravel the dynamic nature of well-being fluctuations and the interaction with the environment in daily life. Integrating all results in this dissertation confirmed that well-being is a complex human trait that is influenced by many interrelated and interacting factors. Future directions to understand individual differences in well-being will be a data-driven approach to investigate the complex interplay of neural, physiological, genetic, and environmental factors in well-being
Introduction to Psychology
Introduction to Psychology is a modified version of Psychology 2e - OpenStax
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