Geometric Modeling of Cellular Materials for Additive Manufacturing in Biomedical Field: A Review

Advances in additive manufacturing technologies facilitate the fabrication of cellular materials that have tailored functional characteristics. The application of solid freeform fabrication techniques is especially exploited in designing scaffolds for tissue engineering. In this review, firstly, a classification of cellular materials from a geometric point of view is proposed; then, the main approaches on geometric modeling of cellular materials are discussed. Finally, an investigation on porous scaffolds fabricated by additive manufacturing technologies is pointed out. Perspectives in geometric modeling of scaffolds for tissue engineering are also proposed

Faster Approximate Diameter and Distance Oracles in Planar Graphs

We present an algorithm that computes a (1+varepsilon)-approximation of the diameter of a weighted, undirected planar graph of n vertices with non-negative edge lengths in O(nlog n(log n + (1/varepsilon)^5)) expected time, improving upon the O(n((1/varepsilon)^4 log^4(n) + 2^{O(1/varepsilon)}))-time algorithm of Weimann and Yuster [ICALP 2013]. Our algorithm makes two improvements over that result: first and foremost, it replaces the exponential dependency on 1/varepsilon with a polynomial one, by adapting and specializing Cabello\u27s recent abstract-Voronoi-diagram-based technique [SODA 2017] for approximation purposes; second, it shaves off two logarithmic factors by choosing a better sequence of error parameters during recursion. Moreover, using similar techniques, we improve the (1+varepsilon)-approximate distance oracle of Gu and Xu [ISAAC 2015] by first replacing the exponential dependency on 1/varepsilon on the preprocessing time and space with a polynomial one and second removing a logarithmic factor from the preprocessing time

Moving Object Trajectories Meta-Model And Spatio-Temporal Queries

In this paper, a general moving object trajectories framework is put forward to allow independent applications processing trajectories data benefit from a high level of interoperability, information sharing as well as an efficient answer for a wide range of complex trajectory queries. Our proposed meta-model is based on ontology and event approach, incorporates existing presentations of trajectory and integrates new patterns like space-time path to describe activities in geographical space-time. We introduce recursive Region of Interest concepts and deal mobile objects trajectories with diverse spatio-temporal sampling protocols and different sensors available that traditional data model alone are incapable for this purpose.Comment: International Journal of Database Management Systems (IJDMS) Vol.4, No.2, April 201

Hierarchical interpolative factorization for elliptic operators: integral equations

This paper introduces the hierarchical interpolative factorization for integral equations (HIF-IE) associated with elliptic problems in two and three dimensions. This factorization takes the form of an approximate generalized LU decomposition that permits the efficient application of the discretized operator and its inverse. HIF-IE is based on the recursive skeletonization algorithm but incorporates a novel combination of two key features: (1) a matrix factorization framework for sparsifying structured dense matrices and (2) a recursive dimensional reduction strategy to decrease the cost. Thus, higher-dimensional problems are effectively mapped to one dimension, and we conjecture that constructing, applying, and inverting the factorization all have linear or quasilinear complexity. Numerical experiments support this claim and further demonstrate the performance of our algorithm as a generalized fast multipole method, direct solver, and preconditioner. HIF-IE is compatible with geometric adaptivity and can handle both boundary and volume problems. MATLAB codes are freely available.Comment: 39 pages, 14 figures, 13 tables; to appear, Comm. Pure Appl. Mat

Hierarchical interpolative factorization for elliptic operators: differential equations

This paper introduces the hierarchical interpolative factorization for elliptic partial differential equations (HIF-DE) in two (2D) and three dimensions (3D). This factorization takes the form of an approximate generalized LU/LDL decomposition that facilitates the efficient inversion of the discretized operator. HIF-DE is based on the multifrontal method but uses skeletonization on the separator fronts to sparsify the dense frontal matrices and thus reduce the cost. We conjecture that this strategy yields linear complexity in 2D and quasilinear complexity in 3D. Estimated linear complexity in 3D can be achieved by skeletonizing the compressed fronts themselves, which amounts geometrically to a recursive dimensional reduction scheme. Numerical experiments support our claims and further demonstrate the performance of our algorithm as a fast direct solver and preconditioner. MATLAB codes are freely available.Comment: 37 pages, 13 figures, 12 tables; to appear, Comm. Pure Appl. Math. arXiv admin note: substantial text overlap with arXiv:1307.266

Minimizing the average distance to a closest leaf in a phylogenetic tree

When performing an analysis on a collection of molecular sequences, it can be convenient to reduce the number of sequences under consideration while maintaining some characteristic of a larger collection of sequences. For example, one may wish to select a subset of high-quality sequences that represent the diversity of a larger collection of sequences. One may also wish to specialize a large database of characterized "reference sequences" to a smaller subset that is as close as possible on average to a collection of "query sequences" of interest. Such a representative subset can be useful whenever one wishes to find a set of reference sequences that is appropriate to use for comparative analysis of environmentally-derived sequences, such as for selecting "reference tree" sequences for phylogenetic placement of metagenomic reads. In this paper we formalize these problems in terms of the minimization of the Average Distance to the Closest Leaf (ADCL) and investigate algorithms to perform the relevant minimization. We show that the greedy algorithm is not effective, show that a variant of the Partitioning Among Medoids (PAM) heuristic gets stuck in local minima, and develop an exact dynamic programming approach. Using this exact program we note that the performance of PAM appears to be good for simulated trees, and is faster than the exact algorithm for small trees. On the other hand, the exact program gives solutions for all numbers of leaves less than or equal to the given desired number of leaves, while PAM only gives a solution for the pre-specified number of leaves. Via application to real data, we show that the ADCL criterion chooses chimeric sequences less often than random subsets, while the maximization of phylogenetic diversity chooses them more often than random. These algorithms have been implemented in publicly available software.Comment: Please contact us with any comments or questions

Geometrical Frustration and Static Correlations in Hard-Sphere Glass Formers

We analytically and numerically characterize the structure of hard-sphere fluids in order to review various geometrical frustration scenarios of the glass transition. We find generalized polytetrahedral order to be correlated with increasing fluid packing fraction, but to become increasingly irrelevant with increasing dimension. We also find the growth in structural correlations to be modest in the dynamical regime accessible to computer simulations.Comment: 21 pages; part of the "Special Topic Issue on the Glass Transition