DESIGN OF A GAIT ACQUISITION AND ANALYSIS SYSTEM FOR ASSESSING THE RECOVERY OF MICE POST-SPINAL CORD INJURY

Current methods of determining spinal cord recovery in mice, post-directed injury, are qualitative measures. This is due to the small size and quickness of mice. This thesis presents a design for a gait acquisition and analysis system able to capture the footfalls of a mouse, extract position and timing data, and report quantitative gait metrics to the operator. These metrics can then be used to evaluate the recovery of the mouse. This work presents the design evolution of the system, from initial sensor design concepts through prototyping and testing to the final implementation. The system utilizes a machine vision camera, a well-designed walkway enclosure, and image processing techniques to capture and analyze paw strikes. Quantitative results gained from live animal experiments are presented, and it is shown how the measurements can be used to determine healthy, injured, and recovered gait

CAPACITANCE METROLOGY OF CURVED SURFACES: STUDY AND CHARACTERIZATION OF A NOVEL PROBE DESIGN

Capacitive sensors are frequently applied to curved target surfaces for precision displacement measurements. In most cases, these sensors have not been recalibrated to take the curvature of the target into consideration. This recalibration becomes more critical as the target surface becomes smaller in comparison to the sensor. Calibration data are presented for a variety of capacitance probe sizes with widely varying geometries. One target surface particularly difficult to characterize is the inner surface of small holes, less than one millimeter in diameter. Although contact probes can successfully measure the inner surface of a hole, these probes are often fragile and require additional sensors to determine when contact occurs. Probes may adhere to the wall of the hole, and only a small number of data points are collected. Direct capacitance measurement of small holes requires a completely new capacitance probe geometry and method of operation. A curved, elongated surface minimizes the gap between the sensor surface and the inner surface of the hole. Reduction in the size of the sensing area is weighed against electronics limitations. The performance of a particular probe geometry is studied using computer simulations to determine the optimal probe design. Multiple, overlapping passes are deconvolved to reveal finer features on the surface of the hole. A prototype sub-millimeter capacitance probe is machined from tungsten carbide, with four additional material layers added using ebeam deposition. Several techniques are studied to remove these layers and create a sensing area along one side of the probe. Both mechanical processes and photolithography are employed

Sensing with Earables: A Systematic Literature Review and Taxonomy of Phenomena

Earables have emerged as a unique platform for ubiquitous computing by augmenting ear-worn devices with state-of-the-art sensing. This new platform has spurred a wealth of new research exploring what can be detected on a wearable, small form factor. As a sensing platform, the ears are less susceptible to motion artifacts and are located in close proximity to a number of important anatomical structures including the brain, blood vessels, and facial muscles which reveal a wealth of information. They can be easily reached by the hands and the ear canal itself is affected by mouth, face, and head movements. We have conducted a systematic literature review of 271 earable publications from the ACM and IEEE libraries. These were synthesized into an open-ended taxonomy of 47 different phenomena that can be sensed in, on, or around the ear. Through analysis, we identify 13 fundamental phenomena from which all other phenomena can be derived, and discuss the different sensors and sensing principles used to detect them. We comprehensively review the phenomena in four main areas of (i) physiological monitoring and health, (ii) movement and activity, (iii) interaction, and (iv) authentication and identification. This breadth highlights the potential that earables have to offer as a ubiquitous, general-purpose platform

MEMS Technology for Biomedical Imaging Applications

Biomedical imaging is the key technique and process to create informative images of the human body or other organic structures for clinical purposes or medical science. Micro-electro-mechanical systems (MEMS) technology has demonstrated enormous potential in biomedical imaging applications due to its outstanding advantages of, for instance, miniaturization, high speed, higher resolution, and convenience of batch fabrication. There are many advancements and breakthroughs developing in the academic community, and there are a few challenges raised accordingly upon the designs, structures, fabrication, integration, and applications of MEMS for all kinds of biomedical imaging. This Special Issue aims to collate and showcase research papers, short commutations, perspectives, and insightful review articles from esteemed colleagues that demonstrate: (1) original works on the topic of MEMS components or devices based on various kinds of mechanisms for biomedical imaging; and (2) new developments and potentials of applying MEMS technology of any kind in biomedical imaging. The objective of this special session is to provide insightful information regarding the technological advancements for the researchers in the community