Refraction-corrected ray-based inversion for three-dimensional ultrasound tomography of the breast

Ultrasound Tomography has seen a revival of interest in the past decade, especially for breast imaging, due to improvements in both ultrasound and computing hardware. In particular, three-dimensional ultrasound tomography, a fully tomographic method in which the medium to be imaged is surrounded by ultrasound transducers, has become feasible. In this paper, a comprehensive derivation and study of a robust framework for large-scale bent-ray ultrasound tomography in 3D for a hemispherical detector array is presented. Two ray-tracing approaches are derived and compared. More significantly, the problem of linking the rays between emitters and receivers, which is challenging in 3D due to the high number of degrees of freedom for the trajectory of rays, is analysed both as a minimisation and as a root-finding problem. The ray-linking problem is parameterised for a convex detection surface and three robust, accurate, and efficient ray-linking algorithms are formulated and demonstrated. To stabilise these methods, novel adaptive-smoothing approaches are proposed that control the conditioning of the update matrices to ensure accurate linking. The nonlinear UST problem of estimating the sound speed was recast as a series of linearised subproblems, each solved using the above algorithms and within a steepest descent scheme. The whole imaging algorithm was demonstrated to be robust and accurate on realistic data simulated using a full-wave acoustic model and an anatomical breast phantom, and incorporating the errors due to time-of-flight picking that would be present with measured data. This method can used to provide a low-artefact, quantitatively accurate, 3D sound speed maps. In addition to being useful in their own right, such 3D sound speed maps can be used to initialise full-wave inversion methods, or as an input to photoacoustic tomography reconstructions

Japan's silver market: creating a new industry under uncertainty

It has often been asked whether today´s Japan will be able to move into new and promising industries, or whether it is locked into an innovation system with an inherent inability to give birth to new industries. One argument reasons that the thick institutional complementarities among labour, innovation, and finance among its enterprises and the public sector favour industrial development in sectors of intermediate uncertainty, while it is difficult to move into areas of major uncertainty. In this paper, we present the case of the silver industry or, somewhat more prosaically, the 60+ or even 50+ industry, for which most would agree that Japan has indeed become a lead market and lead producer on the global market. For an institutional economist, the case of the silver industry is particularly interesting, because Japan´s success is based on the cooperation of existing actors, the enterprise and public sector in particular, which helped overcome the information uncertainties and asymmetries involved in the new market by relying on several established mechanisms developed well before. In that sense, Japan´s silver industry presents a case of of what we propose to call successful institutional path activation with the effect of an innovative market creation, instead of the problematic lockin effects that are usually associated with the term path dependence

Integration by differentiation: new proofs, methods and examples

Recently, new methods were introduced which allow one to solve ordinary integrals by performing only derivatives. These studies were originally motivated by the difficulties of the quantum field theoretic path integral, and correspondingly, the results were derived by heuristic methods. Here, we give rigorous proofs for the methods to hold on fully specified function spaces. We then illustrate the efficacy of the new methods by applying them to the study of the surprising behavior of so-called Borwein integrals.Comment: Match published versio

Kenyon Collegian - January 25, 1990

https://digital.kenyon.edu/collegian/1767/thumbnail.jp

Aspects of the Noisy Burgers Equation

The noisy Burgers equation describing for example the growth of an interface subject to noise is one of the simplest model governing an intrinsically nonequilibrium problem. In one dimension this equation is analyzed by means of the Martin-Siggia-Rose technique. In a canonical formulation the morphology and scaling behavior are accessed by a principle of least action in the weak noise limit. The growth morphology is characterized by a dilute gas of nonlinear soliton modes with gapless dispersion law with exponent z=3/2 and a superposed gas of diffusive modes with a gap. The scaling exponents and a heuristic expression for the scaling function follow from a spectral representation.Comment: 23 pages,LAMUPHYS LaTeX-file (Springer), 13 figures, and 1 table, to appear in the Proceedings of the XI Max Born Symposium on "Anomalous Diffusion: From Basics to Applications", May 20-24, 1998, Ladek Zdroj, Polan