Semantic processing of EHR data for clinical research

There is a growing need to semantically process and integrate clinical data from different sources for clinical research. This paper presents an approach to integrate EHRs from heterogeneous resources and generate integrated data in different data formats or semantics to support various clinical research applications. The proposed approach builds semantic data virtualization layers on top of data sources, which generate data in the requested semantics or formats on demand. This approach avoids upfront dumping to and synchronizing of the data with various representations. Data from different EHR systems are first mapped to RDF data with source semantics, and then converted to representations with harmonized domain semantics where domain ontologies and terminologies are used to improve reusability. It is also possible to further convert data to application semantics and store the converted results in clinical research databases, e.g. i2b2, OMOP, to support different clinical research settings. Semantic conversions between different representations are explicitly expressed using N3 rules and executed by an N3 Reasoner (EYE), which can also generate proofs of the conversion processes. The solution presented in this paper has been applied to real-world applications that process large scale EHR data.Comment: Accepted for publication in Journal of Biomedical Informatics, 2015, preprint versio

Transmission Delay of Multi-hop Heterogeneous Networks for Medical Applications

Nowadays, with increase in ageing population, Health care market keeps growing. There is a need for monitoring of Health issues. Body Area Network consists of wireless sensors attached on or inside human body for monitoring vital Health related problems e.g, Electro Cardiogram (ECG), ElectroEncephalogram (EEG), ElectronyStagmography(ENG) etc. Data is recorded by sensors and is sent towards Health care center. Due to life threatening situations, timely sending of data is essential. For data to reach Health care center, there must be a proper way of sending data through reliable connection and with minimum delay. In this paper transmission delay of different paths, through which data is sent from sensor to Health care center over heterogeneous multi-hop wireless channel is analyzed. Data of medical related diseases is sent through three different paths. In all three paths, data from sensors first reaches ZigBee, which is the common link in all three paths. After ZigBee there are three available networks, through which data is sent. Wireless Local Area Network (WLAN), Worldwide Interoperability for Microwave Access (WiMAX), Universal Mobile Telecommunication System (UMTS) are connected with ZigBee. Each network (WLAN, WiMAX, UMTS) is setup according to environmental conditions, suitability of device and availability of structure for that device. Data from these networks is sent to IP-Cloud, which is further connected to Health care center. Main aim of this paper is to calculate delay of each link in each path over multihop wireless channel.Comment: BioSPAN with 7th IEEE International Conference on Broadband and Wireless Computing, Communication and Applications (BWCCA 2012), Victoria, Canada, 201

A feasibility study for the provision of electronic healthcare tools and services in areas of Greece, Cyprus and Italy

Background: Through this paper, we present the initial steps for the creation of an integrated platform for the provision of a series of eHealth tools and services to both citizens and travelers in isolated areas of thesoutheast Mediterranean, and on board ships travelling across it. The platform was created through an INTERREG IIIB ARCHIMED project called INTERMED. Methods: The support of primary healthcare, home care and the continuous education of physicians are the three major issues that the proposed platform is trying to facilitate. The proposed system is based on state-of-the-art telemedicine systems and is able to provide the following healthcare services: i) Telecollaboration and teleconsultation services between remotely located healthcare providers, ii) telemedicine services in emergencies, iii) home telecare services for "at risk" citizens such as the elderly and patients with chronic diseases, and iv) eLearning services for the continuous training through seminars of both healthcare personnel (physicians, nurses etc) and persons supporting "at risk" citizens. These systems support data transmission over simple phone lines, internet connections, integrated services digital network/digital subscriber lines, satellite links, mobile networks (GPRS/3G), and wireless local area networks. The data corresponds, among others, to voice, vital biosignals, still medical images, video, and data used by eLearning applications. The proposed platform comprises several systems, each supporting different services. These were integrated using a common data storage and exchange scheme in order to achieve system interoperability in terms of software, language and national characteristics. Results: The platform has been installed and evaluated in different rural and urban sites in Greece, Cyprus and Italy. The evaluation was mainly related to technical issues and user satisfaction. The selected sites are, among others, rural health centers, ambulances, homes of "at-risk" citizens, and a ferry. Conclusions: The results proved the functionality and utilization of the platform in various rural places in Greece, Cyprus and Italy. However, further actions are needed to enable the local healthcare systems and the different population groups to be familiarized with, and use in their everyday lives, mature technological solutions for the provision of healthcare services

Future challenges and recommendations

Rapid advances in information technology and telecommunications, and in particular mobile and wireless communications, converge towards the emergence of a new type of “infostructure” that has the potential of supporting a large spectrum of advanced services for healthcare and health. Currently the ICT community produces a great effort to drill down from the vision and the promises of wireless and mobile technologies and provide practical application solutions. Research and development include data gathering and omni-directional transfer of vital information, integration of human machine interface technology into handheld devices and personal applications, security and interoperability of date and integration with hospital legacy systems and electronic patient record. The ongoing evolution of wireless technology and mobile device capabilities is changing the way healthcare providers interact with information technologies. The growth and acceptance of mobile information technology at the point of care, coupled with the promise and convenience of data on demand, creates opportunities for enhanced patient care and safety. The developments presented in this section demonstrate clearly the innovation aspects and trends towards user oriented applications

Analyzing Delay in Wireless Multi-hop Heterogeneous Body Area Networks

With increase in ageing population, health care market keeps growing. There is a need for monitoring of health issues. Wireless Body Area Network (WBAN) consists of wireless sensors attached on or inside human body for monitoring vital health related problems e.g, Electro Cardiogram (ECG), Electro Encephalogram (EEG), ElectronyStagmography (ENG) etc. Due to life threatening situations, timely sending of data is essential. For data to reach health care center, there must be a proper way of sending data through reliable connection and with minimum delay. In this paper transmission delay of different paths, through which data is sent from sensor to health care center over heterogeneous multi-hop wireless channel is analyzed. Data of medical related diseases is sent through three different paths. In all three paths, data from sensors first reaches ZigBee, which is the common link in all three paths. Wireless Local Area Network (WLAN), Worldwide Interoperability for Microwave Access (WiMAX), Universal Mobile Telecommunication System (UMTS) are connected with ZigBee. Each network (WLAN, WiMAX, UMTS) is setup according to environmental conditions, suitability of device and availability of structure for that device. Data from these networks is sent to IP-Cloud, which is further connected to health care center. Delay of data reaching each device is calculated and represented graphically. Main aim of this paper is to calculate delay of each link in each path over multi-hop wireless channel.Comment: arXiv admin note: substantial text overlap with arXiv:1208.240