Semantic processing of EHR data for clinical research

There is a growing need to semantically process and integrate clinical data from different sources for clinical research. This paper presents an approach to integrate EHRs from heterogeneous resources and generate integrated data in different data formats or semantics to support various clinical research applications. The proposed approach builds semantic data virtualization layers on top of data sources, which generate data in the requested semantics or formats on demand. This approach avoids upfront dumping to and synchronizing of the data with various representations. Data from different EHR systems are first mapped to RDF data with source semantics, and then converted to representations with harmonized domain semantics where domain ontologies and terminologies are used to improve reusability. It is also possible to further convert data to application semantics and store the converted results in clinical research databases, e.g. i2b2, OMOP, to support different clinical research settings. Semantic conversions between different representations are explicitly expressed using N3 rules and executed by an N3 Reasoner (EYE), which can also generate proofs of the conversion processes. The solution presented in this paper has been applied to real-world applications that process large scale EHR data.Comment: Accepted for publication in Journal of Biomedical Informatics, 2015, preprint versio

Proximal business intelligence on the semantic web

This is the post-print version of this article. The official version can be accessed from the link below - Copyright @ 2010 Springer.Ubiquitous information systems (UBIS) extend current Information System thinking to explicitly differentiate technology between devices and software components with relation to people and process. Adapting business data and management information to support specific user actions in context is an ongoing topic of research. Approaches typically focus on providing mechanisms to improve specific information access and transcoding but not on how the information can be accessed in a mobile, dynamic and ad-hoc manner. Although web ontology has been used to facilitate the loading of data warehouses, less research has been carried out on ontology based mobile reporting. This paper explores how business data can be modeled and accessed using the web ontology language and then re-used to provide the invisibility of pervasive access; uncovering more effective architectural models for adaptive information system strategies of this type. This exploratory work is guided in part by a vision of business intelligence that is highly distributed, mobile and fluid, adapting to sensory understanding of the underlying environment in which it operates. A proof-of concept mobile and ambient data access architecture is developed in order to further test the viability of such an approach. The paper concludes with an ontology engineering framework for systems of this type – named UBIS-ONTO

ASPECTS REGARDING THE INTEGRATION OF THE MODERN INFORMATION SYSTEMS

Developing an information system integration strategy, at enterprise level is one of the most difficult issues that the information systems managers must solve, within the present conditions. When settling the integration strategy, two aspects must mainly be taken into account: assuring a complete integration solution of the information systems and building an integration infrastructure of the applications. The present paper aims at presenting few aspects regarding the integration of the information systems at organizational level and describing a specifically developed IBM architecture.information systems integration, software modelling, Model Driven Architecture (MDA), Model Driven Development (MDD)

Significance of Trans-European Transport Networks for Logistics Centre Localization as Exemplified by the Łódź Region

This work complements and structures knowledge in the field of logistics centres (with focus on the Łódź region). It presents a thorough analysis of strategic documents of the European Union in reference to the functioning of international transport networks. It also provides a detailed description of logistics facilities operations from the theoretical standpoint and definition of relations in points where logistics centres and TEN-T networks overlap. The result of this work is a set of recommendations referring to effective development of logistics centres on the background of transport corridors

Optimization on emergency materials dispatching considering the characteristics of integrated emergency response for large-scale marine oil spills

Many governments have been strengthening the construction of hardware facilities and equipment to prevent and control marine oil spills. However, in order to deal with large-scale marine oil spills more efficiently, emergency materials dispatching algorithm still needs further optimization. The present study presents a methodology for emergency materials dispatching optimization based on four steps, combined with the construction of Chinese oil spill response capacity. First, the present emergency response procedure for large-scale marine oil spills should be analyzed. Second, in accordance with different grade accidents, the demands of all kinds of emergency materials are replaced by an equivalent volume that can unify the units. Third, constraint conditions of the emergency materials dispatching optimization model should be presented, and the objective function of the model should be postulated with the purpose of minimizing the largest sailing time of all oil spill emergency disposal vessels, and the difference in sailing time among vessels that belong to the same emergency materials collection and distribution point. Finally, the present study applies a toolbox and optimization solver to optimize the emergency materials dispatching problem. A calculation example is presented, highlighting the sensibility of the results at different grades of oil spills. The present research would be helpful for emergency managers in tackling an efficient materials dispatching scheme, while considering the integrated emergency response procedure.Peer ReviewedPostprint (published version