1,764 research outputs found

    Robust and Flexible Persistent Scatterer Interferometry for Long-Term and Large-Scale Displacement Monitoring

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    Die Persistent Scatterer Interferometrie (PSI) ist eine Methode zur Überwachung von Verschiebungen der Erdoberfläche aus dem Weltraum. Sie basiert auf der Identifizierung und Analyse von stabilen Punktstreuern (sog. Persistent Scatterer, PS) durch die Anwendung von Ansätzen der Zeitreihenanalyse auf Stapel von SAR-Interferogrammen. PS Punkte dominieren die Rückstreuung der Auflösungszellen, in denen sie sich befinden, und werden durch geringfügige Dekorrelation charakterisiert. Verschiebungen solcher PS Punkte können mit einer potenziellen Submillimetergenauigkeit überwacht werden, wenn Störquellen effektiv minimiert werden. Im Laufe der Zeit hat sich die PSI in bestimmten Anwendungen zu einer operationellen Technologie entwickelt. Es gibt jedoch immer noch herausfordernde Anwendungen für die Methode. Physische Veränderungen der Landoberfläche und Änderungen in der Aufnahmegeometrie können dazu führen, dass PS Punkte im Laufe der Zeit erscheinen oder verschwinden. Die Anzahl der kontinuierlich kohärenten PS Punkte nimmt mit zunehmender Länge der Zeitreihen ab, während die Anzahl der TPS Punkte zunimmt, die nur während eines oder mehrerer getrennter Segmente der analysierten Zeitreihe kohärent sind. Daher ist es wünschenswert, die Analyse solcher TPS Punkte in die PSI zu integrieren, um ein flexibles PSI-System zu entwickeln, das in der Lage ist mit dynamischen Veränderungen der Landoberfläche umzugehen und somit ein kontinuierliches Verschiebungsmonitoring ermöglicht. Eine weitere Herausforderung der PSI besteht darin, großflächiges Monitoring in Regionen mit komplexen atmosphärischen Bedingungen durchzuführen. Letztere führen zu hoher Unsicherheit in den Verschiebungszeitreihen bei großen Abständen zur räumlichen Referenz. Diese Arbeit befasst sich mit Modifikationen und Erweiterungen, die auf der Grund lage eines bestehenden PSI-Algorithmus realisiert wurden, um einen robusten und flexiblen PSI-Ansatz zu entwickeln, der mit den oben genannten Herausforderungen umgehen kann. Als erster Hauptbeitrag wird eine Methode präsentiert, die TPS Punkte vollständig in die PSI integriert. In Evaluierungsstudien mit echten SAR Daten wird gezeigt, dass die Integration von TPS Punkten tatsächlich die Bewältigung dynamischer Veränderungen der Landoberfläche ermöglicht und mit zunehmender Zeitreihenlänge zunehmende Relevanz für PSI-basierte Beobachtungsnetzwerke hat. Der zweite Hauptbeitrag ist die Vorstellung einer Methode zur kovarianzbasierten Referenzintegration in großflächige PSI-Anwendungen zur Schätzung von räumlich korreliertem Rauschen. Die Methode basiert auf der Abtastung des Rauschens an Referenzpixeln mit bekannten Verschiebungszeitreihen und anschließender Interpolation auf die restlichen PS Pixel unter Berücksichtigung der räumlichen Statistik des Rauschens. Es wird in einer Simulationsstudie sowie einer Studie mit realen Daten gezeigt, dass die Methode überlegene Leistung im Vergleich zu alternativen Methoden zur Reduktion von räumlich korreliertem Rauschen in Interferogrammen mittels Referenzintegration zeigt. Die entwickelte PSI-Methode wird schließlich zur Untersuchung von Landsenkung im Vietnamesischen Teil des Mekong Deltas eingesetzt, das seit einigen Jahrzehnten von Landsenkung und verschiedenen anderen Umweltproblemen betroffen ist. Die geschätzten Landsenkungsraten zeigen eine hohe Variabilität auf kurzen sowie großen räumlichen Skalen. Die höchsten Senkungsraten von bis zu 6 cm pro Jahr treten hauptsächlich in städtischen Gebieten auf. Es kann gezeigt werden, dass der größte Teil der Landsenkung ihren Ursprung im oberflächennahen Untergrund hat. Die präsentierte Methode zur Reduzierung von räumlich korreliertem Rauschen verbessert die Ergebnisse signifikant, wenn eine angemessene räumliche Verteilung von Referenzgebieten verfügbar ist. In diesem Fall wird das Rauschen effektiv reduziert und unabhängige Ergebnisse von zwei Interferogrammstapeln, die aus unterschiedlichen Orbits aufgenommen wurden, zeigen große Übereinstimmung. Die Integration von TPS Punkten führt für die analysierte Zeitreihe von sechs Jahren zu einer deutlich größeren Anzahl an identifizierten TPS als PS Punkten im gesamten Untersuchungsgebiet und verbessert damit das Beobachtungsnetzwerk erheblich. Ein spezieller Anwendungsfall der TPS Integration wird vorgestellt, der auf der Clusterung von TPS Punkten basiert, die innerhalb der analysierten Zeitreihe erschienen, um neue Konstruktionen systematisch zu identifizieren und ihre anfängliche Bewegungszeitreihen zu analysieren

    Flood dynamics derived from video remote sensing

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    Flooding is by far the most pervasive natural hazard, with the human impacts of floods expected to worsen in the coming decades due to climate change. Hydraulic models are a key tool for understanding flood dynamics and play a pivotal role in unravelling the processes that occur during a flood event, including inundation flow patterns and velocities. In the realm of river basin dynamics, video remote sensing is emerging as a transformative tool that can offer insights into flow dynamics and thus, together with other remotely sensed data, has the potential to be deployed to estimate discharge. Moreover, the integration of video remote sensing data with hydraulic models offers a pivotal opportunity to enhance the predictive capacity of these models. Hydraulic models are traditionally built with accurate terrain, flow and bathymetric data and are often calibrated and validated using observed data to obtain meaningful and actionable model predictions. Data for accurately calibrating and validating hydraulic models are not always available, leaving the assessment of the predictive capabilities of some models deployed in flood risk management in question. Recent advances in remote sensing have heralded the availability of vast video datasets of high resolution. The parallel evolution of computing capabilities, coupled with advancements in artificial intelligence are enabling the processing of data at unprecedented scales and complexities, allowing us to glean meaningful insights into datasets that can be integrated with hydraulic models. The aims of the research presented in this thesis were twofold. The first aim was to evaluate and explore the potential applications of video from air- and space-borne platforms to comprehensively calibrate and validate two-dimensional hydraulic models. The second aim was to estimate river discharge using satellite video combined with high resolution topographic data. In the first of three empirical chapters, non-intrusive image velocimetry techniques were employed to estimate river surface velocities in a rural catchment. For the first time, a 2D hydraulicvmodel was fully calibrated and validated using velocities derived from Unpiloted Aerial Vehicle (UAV) image velocimetry approaches. This highlighted the value of these data in mitigating the limitations associated with traditional data sources used in parameterizing two-dimensional hydraulic models. This finding inspired the subsequent chapter where river surface velocities, derived using Large Scale Particle Image Velocimetry (LSPIV), and flood extents, derived using deep neural network-based segmentation, were extracted from satellite video and used to rigorously assess the skill of a two-dimensional hydraulic model. Harnessing the ability of deep neural networks to learn complex features and deliver accurate and contextually informed flood segmentation, the potential value of satellite video for validating two dimensional hydraulic model simulations is exhibited. In the final empirical chapter, the convergence of satellite video imagery and high-resolution topographical data bridges the gap between visual observations and quantitative measurements by enabling the direct extraction of velocities from video imagery, which is used to estimate river discharge. Overall, this thesis demonstrates the significant potential of emerging video-based remote sensing datasets and offers approaches for integrating these data into hydraulic modelling and discharge estimation practice. The incorporation of LSPIV techniques into flood modelling workflows signifies a methodological progression, especially in areas lacking robust data collection infrastructure. Satellite video remote sensing heralds a major step forward in our ability to observe river dynamics in real time, with potentially significant implications in the domain of flood modelling science

    Novel insights into the isolation of extracellular vesicles by anion exchange chromatography

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    Extracellular vesicles (EVs) are membrane structures enclosed by a lipid bilayer that are released into the extracellular space by all types of cells. EVs are involved in many physiological processes by transporting biologically active substances. Interest in EVs for diagnostic biomarker research and therapeutic drug delivery applications has increased in recent years. The realization of the full therapeutic potential of EVs is currently hampered by the lack of a suitable technology for the isolation and purification of EVs for downstream pharmaceutical applications. Anion Exchange Chromatography (AEX) is an established method in which specific charges on the AEX matrix can exploit charges on the surface of EVs and their interactions to provide a productive and scalable separation and purification method. The established AEX method using Eshmuno® Q, a strong tentacle anion exchange resin, was used to demonstrate the principal feasibility of AEX-based isolation and gain insight into isolated EV properties. Using several EV analysis techniques to provide a more detailed insight into EV populations during AEX isolation, we demonstrated that although the composition of CD9/63/81 remained constant for tetraspanin positive EVs, the size distribution and purity changed during elution. Higher salt concentrations eluted larger tetraspanin negative vesicles

    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

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    Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly

    Satellite remote sensing of surface winds, waves, and currents: Where are we now?

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    This review paper reports on the state-of-the-art concerning observations of surface winds, waves, and currents from space and their use for scientific research and subsequent applications. The development of observations of sea state parameters from space dates back to the 1970s, with a significant increase in the number and diversity of space missions since the 1990s. Sensors used to monitor the sea-state parameters from space are mainly based on microwave techniques. They are either specifically designed to monitor surface parameters or are used for their abilities to provide opportunistic measurements complementary to their primary purpose. The principles on which is based on the estimation of the sea surface parameters are first described, including the performance and limitations of each method. Numerous examples and references on the use of these observations for scientific and operational applications are then given. The richness and diversity of these applications are linked to the importance of knowledge of the sea state in many fields. Firstly, surface wind, waves, and currents are significant factors influencing exchanges at the air/sea interface, impacting oceanic and atmospheric boundary layers, contributing to sea level rise at the coasts, and interacting with the sea-ice formation or destruction in the polar zones. Secondly, ocean surface currents combined with wind- and wave- induced drift contribute to the transport of heat, salt, and pollutants. Waves and surface currents also impact sediment transport and erosion in coastal areas. For operational applications, observations of surface parameters are necessary on the one hand to constrain the numerical solutions of predictive models (numerical wave, oceanic, or atmospheric models), and on the other hand to validate their results. In turn, these predictive models are used to guarantee safe, efficient, and successful offshore operations, including the commercial shipping and energy sector, as well as tourism and coastal activities. Long-time series of global sea-state observations are also becoming increasingly important to analyze the impact of climate change on our environment. All these aspects are recalled in the article, relating to both historical and contemporary activities in these fields

    Undergraduate Catalog of Studies, 2022-2023

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    Investigating the Backscatter of Marine Plastic Litter Using a C- and X-Band Ground Radar, during a Measurement Campaign in Deltares

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    In recent years, marine plastic pollution has seen increased coverage in the public interest and research due to a greater understanding of the scale and impact of plastic pollution within the marine environment. Considering the hazard that plastic waste poses on the environment, marine life, and on humans, remote-sensing techniques could provide timely information on their detection and dynamics. The remote sensing of marine plastic is a relatively new field and research into the capabilities of radar for detecting and monitoring marine plastic pollution is generally limited, with several interactions and mechanisms being largely unknown. Here, we exploit the use of a C- and X-band radar to understand the capabilities of monitoring marine plastics. Our results show that backscattering differences in the C- and X-band between the reference water (called here as “clean”) and the test water filled with plastic can be detected in some conditions (based on statistical analysis). Overall, the results indicate that the X-band frequency performs significantly better than the C-band frequency, with X-band detecting significant differences in backscattering in 48/68 test cases compared with C-band detecting differences in 20/67 test cases. We also find that the difference in backscattering is dependent on the size and shape of the plastic object, as well as the wave conditions which the plastic is moving on. This study provides new insights on the radar capabilities for detecting marine plastic litter and new information which can be used in the planning of future missions and studies on the remote sensing of marine plastic pollution

    Spatial frequency domain imaging towards improved detection of gastrointestinal cancers

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    Early detection and treatment of gastrointestinal cancers has been shown to drastically improve patients survival rates. However, wide population based screening for gastrointestinal cancers is not feasible due to its high cost, risk of potential complications, and time consuming nature. This thesis forms the proposal for the development of a cost-effective, minimally invasive device to return quantitative tissue information for gastrointestinal cancer detection in-vivo using spatial frequency domain imaging (SFDI). SFDI is a non-invasive imaging technique which can return close to real time maps of absorption and reduced scattering coefficients by projecting a 2D sinusoidal pattern onto a sample of interest. First a low-cost, conventional bench top system was constructed to characterise tissue mimicking phantoms. Phantoms were fabricated with specific absorption and reduced scattering coefficients, mimicking the variation in optical properties typically seen in healthy, cancerous, and pre-cancerous oesophageal tissue. The system shows accurate retrieval of absorption and reduced scattering coefficients of 19% and 11% error respectively. However, this bench top system consists of a bulky projector and is therefore not feasible for in-vivo imaging. For SFDI systems to be feasible for in-vivo imaging, they are required to be miniaturised. Many conditions must be considered when doing this such as various illumination conditions, lighting conditions and system geometries. Therefore to aid in the miniaturisation of the bench top system, an SFDI system was simulated in the open-source ray tracing software Blender, where the capability to simulate these conditions is possible. A material of tunable absorption and scattering properties was characterised such that the specific absorption and reduced scattering coefficients of the material were known. The simulated system shows capability in detecting optical properties of typical gastrointestinal conditions in an up-close, planar geometry, as well in a non-planar geometry of a tube simulating a lumen. Optical property imaging in the non-planar, tubular geometry was done with the use of a novel illumination pattern, developed for this work. Finally, using the knowledge gained from the simulation model, the bench top system was miniaturised to a 3 mm diameter prototype. The novel use of a fiber array producing the necessary interfering fringe patterns replaced the bulky projector. The system showed capability to image phantoms simulating typical gastrointestinal conditions at two wavelengths (515 and 660 nm), measuring absorption and reduced scattering coefficients with 15% and 6% accuracy in comparison to the bench top system for the fabricated phantoms. It is proposed that this system may be used for cost-effective, minimally invasive, quantitative imaging of the gastrointestinal tract in-vivo, providing enhanced contrast for difficult to detect cancers

    Observing glacier elevation changes from spaceborne optical and radar sensors – an inter-comparison experiment using ASTER and TanDEM-X data

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    Observations of glacier mass changes are key to understanding the response of glaciers to climate change and related impacts, such as regional runoff, ecosystem changes, and global sea-level rise. Spaceborne optical and radar sensors make it possible to quantify glacier elevation changes, and thus multi-annual mass changes, on a regional and global scale. However, estimates from a growing number of studies show a wide range of results with differences often beyond uncertainty bounds. Here, we present the outcome of a community-based inter-comparison experiment using spaceborne optical stereo (ASTER) and synthetic aperture radar interferometry (TanDEM-X) data to estimate elevation changes for defined glaciers and target periods that pose different assessment challenges. Using provided or self-processed digital elevation models (DEMs) for five test sites, 12 research groups provided a total of 97 spaceborne elevation-change datasets using various processing strategies. Validation with airborne data showed that using an ensemble estimate is promising to reduce random errors from different instruments and processing methods, but still requires a more comprehensive investigation and correction of systematic errors. We found that scene selection, DEM processing, and co-registration have the biggest impact on the results. Other processing steps, such as treating spatial data voids, differences in survey periods, or radar penetration, can still be important for individual cases. Future research should focus on testing different implementations of individual processing steps (e.g. co-registration) and addressing issues related to temporal corrections, radar penetration, glacier area changes, and density conversion. Finally, there is a clear need for our community to develop best practices, use open, reproducible software, and assess overall uncertainty in order to enhance inter-comparison and empower physical process insights across glacier elevation-change studies
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