The Centre for Chemical Sensors/Biosensors and bioAnalytical Chemistry, CCS, at the Interface between Science and the Market Place

In the following article, a very brief overview describing the general strategies and the main goals tackled by CCS is given. The latest news, as well as projects running in collaboration with companies are not discussed here. For more details see homepage, http://www.chemsens.ethz.ch

Crossing (or not?) the 'valley of death': University-industry collaborative e-platforms

The publication is available to ISPIM members at www.ispim.org.In the today’s era of the two-sided markets, the online knowledge market places (as yet2.com) are developing rapidly. Given the importance of the academia-business interface, for the economic development these online tools now emerge to assist knowledge transfer also between academia and business. However, despite their potential, the online marketplaces or platforms for university-industry innovation remain unexplored from a research perspective – although at least three streams of literature try to tackle this phenomenon to a certain extent: economics, sociology and computer science. Using nine case studies of such platforms from across the globe, we explore in-depth their role in crossing the ‘valley of death’ between academia and business. Analysing the academia-business online knowledge transfer intermediaries through the lenses of economics, sociology and computer science, we outline the theoretical scope of this emerging phenomenon, its key characteristics and share managerial as well as policy implications on its contribution to ‘crossing the death valley’

Automatic generation of hardware/software interfaces

Enabling new applications for mobile devices often requires the use of specialized hardware to reduce power consumption. Because of time-to-market pressure, current design methodologies for embedded applications require an early partitioning of the design, allowing the hardware and software to be developed simultaneously, each adhering to a rigid interface contract. This approach is problematic for two reasons: (1) a detailed hardware-software interface is difficult to specify until one is deep into the design process, and (2) it prevents the later migration of functionality across the interface motivated by efficiency concerns or the addition of features. We address this problem using the Bluespec Codesign Language~(BCL) which permits the designer to specify the hardware-software partition in the source code, allowing the compiler to synthesize efficient software and hardware along with transactors for communication between the partitions. The movement of functionality across the hardware-software boundary is accomplished by simply specifying a new partitioning, and since the compiler automatically generates the desired interface specifications, it eliminates yet another error-prone design task. In this paper we present BCL, an extension of a commercially available hardware design language (Bluespec SystemVerilog), a new software compiling scheme, and preliminary results generated using our compiler for various hardware-software decompositions of an Ogg Vorbis audio decoder, and a ray-tracing application.National Science Foundation (U.S.) (NSF (#CCF-0541164))National Research Foundation of Korea (grant from the Korean Government (MEST) (#R33-10095)

The determinants of the quality of Sales-Marketing Interface in a Multinational Customer Brand Focused Company: The Latin American Branches

Customer evolution and changes in consumers, determine the fact that the quality of the interface between marketing and sales may represent a true competitive advantage for the firm. Building on multidimensional theoretical and empirical models developed in Europe and on social network analysis, the organizational interface between the marketing and sales departments of a multinational high-growth company with operations in Argentina, Uruguay and Paraguay is studied. Both, attitudinal and social network measures of information exchange are used to make operational the nature and quality of the interface and its impact on performance. Results show the existence of a positive relationship of formalization, joint planning, teamwork, trust and information transfer on interface quality, as well as a positive relationship between interface quality and business performance. We conclude that efficient design and organizational management of the exchange network are essential for the successful performance of consumer goods companies that seek to develop distinctive capabilities to adapt to markets that experience vertiginous change

Farming Differentiation in the Rural-urban Interface of the Middle Mountains, Nepal: Application of Analytic Hierarchy Process (AHP)Modeling

This article investigates the dominant factors of farming differentiation in the rural-urban interface of the densely populated Kathmandu Valley, using the Analytic Hierarchy Process (AHP) modeling. The rural-urban interface in the Kathmandu Valley is an important vegetable production pocket which supplies a large amount of the vegetables in the city core. While subsistence farming in the rural area is characterized by a system which integrates livestock and forestry with agriculture, the intensification in the urban fringe is characterized by triple crop rotations and market-oriented intensive vegetable production. Seven factors which were supposed to cause farming variation in the interface were incorporated in the AHP framework and then subjected to the farmers’ judgment in distinctly delineated three farming zones. These factors played crucial yet differing roles in different farming zones. Inaccessibility and use of local resources; higher yield and accessibility and agro-ecological consideration and quality production are the key impacting factors of subsistence, commercial inorganic and smallholder organic farming respectively. The quantification of such factors of farming differentiation through AHP is an important piece of information that will contribute in modeling farming in the rural-urban interface of developing countries which are characterized by a high diversity of farming practices and are undergoing a rapid change in the land use pattern

Evaluation of polyelectrolyte multilayer thin-film coated microneedle arrays for transcutaneous vaccine delivery

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 43-46).The skin is an ideal organ for the safe and convenient delivery of vaccines, small molecules, and other biologics. Members of the Irvine and Hammond groups have developed a polyelectrolyte multilayer thin film-coated microneedle platform that can achieve simultaneous DNA and nanoparticle delivery. This delivery platform has the advantage of direct delivery of DNA or polymer nanoparticles to immune-active cells at the interface between the dermis and epidermis, enhancing uptake of the delivered cargo by resident immune cells. Ideal for the delivery of DNA vaccines, this platform aims to bridge the gap in the lack of efficient delivery platforms hampering the effectiveness of DNA vaccines. The ability to co-deliver polymer nanoparticles can serve as a conduit for delivering immune stimulating adjuvants or other drugs for therapeutic applications. An overview of current vaccine and delivery system research is presented. Market factors for the commercialization of the polyelectrolyte multilayer thin film-coated microneedle delivery platform are considered along with the risk factors in bringing this invention to market. An assessment of the intellectual property surrounding the platform is performed and a preliminary market entry strategy is developed for minimizing the risks commercialization.by Peter W. Fung.M.Eng

A relational insight of brand personification in business-to-business markets

Customers find it difficult to differentiate between competing products based on their functional aspects. The shortening life cycle of products due to quick adoption of technological innovations by competitors makes it difficult for them to identify products based on specifications. The contemporary academic literature related to relationship marketing and brand management is passionate about customer and consumer psychology but little attention has been given to the brand selection criteria of resellers as business customers of the brand. This paper combines branding and relationship marketing as two broad functions of marketing. The paper argues upon the role of human representatives of the brand as brand personified in managing these two functions of marketing in business-to-business markets. The proposal of the paper is to use human representatives as a tool for the execution of relationship marketing and branding strategies. The objective behind using human representatives is to maximize the mindshare of resellers towards the brand and create value for them beyond products and service

Mirroring or misting: On the role of product architecture, product complexity, and the rate of product component change

This paper contributes to the literature on the within-firm and across-firm mirroring hypothesis – the assumed architectural mapping between firms’ strategic choices of product architecture and firm architecture, and between firms’ architectural choices and the industry structures that emerge. Empirical evidence is both limited and mixed and there is evidently a need for a more nuanced theory that embeds not only whether the mirroring hypothesis holds, but under what product architecture and component-level conditions it may or may not hold. We invoke an industrial economics perspective to develop a stylised product architecture typology and hypothesise how the combined effects of product architecture type, product complexity and the rate of product component change may be associated with phases of mirroring or misting. Our framework helps to reconcile much existing mixed evidence and provides the foundation for further empirical research

Ontology-Based Recommendation of Editorial Products

Major academic publishers need to be able to analyse their vast catalogue of products and select the best items to be marketed in scientific venues. This is a complex exercise that requires characterising with a high precision the topics of thousands of books and matching them with the interests of the relevant communities. In Springer Nature, this task has been traditionally handled manually by publishing editors. However, the rapid growth in the number of scientific publications and the dynamic nature of the Computer Science landscape has made this solution increasingly inefficient. We have addressed this issue by creating Smart Book Recommender (SBR), an ontology-based recommender system developed by The Open University (OU) in collaboration with Springer Nature, which supports their Computer Science editorial team in selecting the products to market at specific venues. SBR recommends books, journals, and conference proceedings relevant to a conference by taking advantage of a semantically enhanced representation of about 27K editorial products. This is based on the Computer Science Ontology, a very large-scale, automatically generated taxonomy of research areas. SBR also allows users to investigate why a certain publication was suggested by the system. It does so by means of an interactive graph view that displays the topic taxonomy of the recommended editorial product and compares it with the topic-centric characterization of the input conference. An evaluation carried out with seven Springer Nature editors and seven OU researchers has confirmed the effectiveness of the solution