8,891 research outputs found

    Extending remote patient monitoring with mobile real time clinical decision support

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    Large scale implementation of telemedicine services such as telemonitoring and teletreatment will generate huge amounts of clinical data. Even small amounts of data from continuous patient monitoring cannot be scrutinised in real time and round the clock by health professionals. In future huge volumes of such data will have to be routinely screened by intelligent software systems. We investigate how to make m-health systems for ambulatory care more intelligent by applying a Decision Support approach in the analysis and interpretation of biosignal data and to support adherence to evidence-based best practice such as is expressed in treatment protocols and clinical practice guidelines. The resulting Clinical Decision Support Systems must be able to accept and interpret real time streaming biosignals and context data as well as the patient’s (relatively less dynamic) clinical and administrative data. In this position paper we describe the telemonitoring/teletreatment system developed at the University of Twente, based on Body Area Network (BAN) technology, and present our vision of how BAN-based telemedicine services can be enhanced by incorporating mobile real time Clinical Decision Support. We believe that the main innovative aspects of the vision relate to the implementation of decision support on a mobile platform; incorporation of real time input and analysis of streaming\ud biosignals into the inferencing process; implementation of decision support in a distributed system; and the consequent challenges such as maintenance of consistency of knowledge, state and beliefs across a distributed environment

    Matching pursuit-based compressive sensing in a wearable biomedical accelerometer fall diagnosis device

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    There is a significant high fall risk population, where individuals are susceptible to frequent falls and obtaining significant injury, where quick medical response and fall information are critical to providing efficient aid. This article presents an evaluation of compressive sensing techniques in an accelerometer-based intelligent fall detection system modelled on a wearable Shimmer biomedical embedded computing device with Matlab. The presented fall detection system utilises a database of fall and activities of daily living signals evaluated with discrete wavelet transforms and principal component analysis to obtain binary tree classifiers for fall evaluation. 14 test subjects undertook various fall and activities of daily living experiments with a Shimmer device to generate data for principal component analysis-based fall classifiers and evaluate the proposed fall analysis system. The presented system obtains highly accurate fall detection results, demonstrating significant advantages in comparison with the thresholding method presented. Additionally, the presented approach offers advantageous fall diagnostic information. Furthermore, transmitted data accounts for over 80% battery current usage of the Shimmer device, hence it is critical the acceleration data is reduced to increase transmission efficiency and in-turn improve battery usage performance. Various Matching pursuit-based compressive sensing techniques have been utilised to significantly reduce acceleration information required for transmission.Scopu

    Classification of Epileptic EEG Signals by Wavelet based CFC

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    Electroencephalogram, an influential equipment for analyzing humans activities and recognition of seizure attacks can play a crucial role in designing accurate systems which can distinguish ictal seizures from regular brain alertness, since it is the first step towards accomplishing a high accuracy computer aided diagnosis system (CAD). In this article a novel approach for classification of ictal signals with wavelet based cross frequency coupling (CFC) is suggested. After extracting features by wavelet based CFC, optimal features have been selected by t-test and quadratic discriminant analysis (QDA) have completed the Classification.Comment: Electroencephalogram; Wavelet Decomposition; Cross Frequency Coupling;Quadratic Discriminant Analysis; T-test Feature Selectio

    Vision and Reading Difficulties Part 1: Specific learning difficulties and vision

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    This article is the first in a series of five about vision and reading difficulties, and provides an introduction and an overview of learning disabilities and specific learning difficulties. It outlines the role of the optometrist in helping people with such problems; it describes the symptoms that optometrists should look for and it provides an introduction of the evidence-based approach. The second article in this series will cover the optometric and orthoptic correlates of reading difficulties. Articles three and four will describe the use of coloured filters, including background, techniques, evidence, and mechanism. The final article will draw together the themes in the series of articles and discuss the clinical protocol and the role of the eye care practitioner in managing visual factors associated with reading difficulties

    Realization of Analog Wavelet Filter using Hybrid Genetic Algorithm for On-line Epileptic Event Detection

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    © 2020 The Author(s). This open access work is licensed under a Creative Commons Attribution 4.0 License. For more information, see http://creativecommons.org/licenses/by/4.0/.As the evolution of traditional electroencephalogram (EEG) monitoring unit for epilepsy diagnosis, wearable ambulatory EEG (WAEEG) system transmits EEG data wirelessly, and can be made miniaturized, discrete and social acceptable. To prolong the battery lifetime, analog wavelet filter is used for epileptic event detection in WAEEG system to achieve on-line data reduction. For mapping continuous wavelet transform to analog filter implementation with low-power consumption and high approximation accuracy, this paper proposes a novel approximation method to construct the wavelet base in analog domain, in which the approximation process in frequency domain is considered as an optimization problem by building a mathematical model with only one term in the numerator. The hybrid genetic algorithm consisting of genetic algorithm and quasi-Newton method is employed to find the globally optimum solution, taking required stability into account. Experiment results show that the proposed method can give a stable analog wavelet base with simple structure and higher approximation accuracy compared with existing method, leading to a better spike detection accuracy. The fourth-order Marr wavelet filter is designed as an example using Gm-C filter structure based on LC ladder simulation, whose power consumption is only 33.4 pW at 2.1Hz. Simulation results show that the design method can be used to facilitate low power and small volume implementation of on-line epileptic event detector.Peer reviewe

    Graph-Sparse LDA: A Topic Model with Structured Sparsity

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    Originally designed to model text, topic modeling has become a powerful tool for uncovering latent structure in domains including medicine, finance, and vision. The goals for the model vary depending on the application: in some cases, the discovered topics may be used for prediction or some other downstream task. In other cases, the content of the topic itself may be of intrinsic scientific interest. Unfortunately, even using modern sparse techniques, the discovered topics are often difficult to interpret due to the high dimensionality of the underlying space. To improve topic interpretability, we introduce Graph-Sparse LDA, a hierarchical topic model that leverages knowledge of relationships between words (e.g., as encoded by an ontology). In our model, topics are summarized by a few latent concept-words from the underlying graph that explain the observed words. Graph-Sparse LDA recovers sparse, interpretable summaries on two real-world biomedical datasets while matching state-of-the-art prediction performance
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