130,737 research outputs found
Public or private economies of knowledge: The economics of diffusion and appropriation of bioinformatics tools
The past three decades have witnessed a period of great turbulence in the economies of biological knowledge, during which there has been great uncertainty as to how and where boundaries could be drawn between public or private knowledge especially with regard to the explosive growth in biological databases and their related bioinformatic tools. This paper will focus on some of the key software tools developed in relation to bio-databases. It will argue that bioinformatic tools are particularly economically unstable, and that there is a continuing tension and competition between their public and private modes of production, appropriation, distribution, and use. The paper adopts an ?instituted economic process? approach, and in this paper will elaborate on processes of making knowledge public in the creation of ?public goods?. The question is one of continuously creating and sustaining new institutions of the commons. We believe this critical to an understanding of the division and interdependency between public and private economies of knowledge
The Serums Tool-Chain:Ensuring Security and Privacy of Medical Data in Smart Patient-Centric Healthcare Systems
Digital technology is permeating all aspects of human society and life. This leads to humans becoming highly dependent on digital devices, including upon digital: assistance, intelligence, and decisions. A major concern of this digital dependence is the lack of human oversight or intervention in many of the ways humans use this technology. This dependence and reliance on digital technology raises concerns in how humans trust such systems, and how to ensure digital technology behaves appropriately. This works considers recent developments and projects that combine digital technology and artificial intelligence with human society. The focus is on critical scenarios where failure of digital technology can lead to significant harm or even death. We explore how to build trust for users of digital technology in such scenarios and considering many different challenges for digital technology. The approaches applied and proposed here address user trust along many dimensions and aim to build collaborative and empowering use of digital technologies in critical aspects of human society
Nanoinformatics: developing new computing applications for nanomedicine
Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges. While nanomaterials open up the possibility for developing new devices in many industrial and scientific areas, they also offer breakthrough perspectives for the prevention, diagnosis and treatment of diseases. In this paper, we analyze the different aspects of nanoinformatics and suggest five research topics to help catalyze new research and development in the area, particularly focused on nanomedicine. We also encompass the use of informatics to further the biological and clinical applications of basic research in nanoscience and nanotechnology, and the related concept of an extended ?nanotype? to coalesce information related to nanoparticles. We suggest how nanoinformatics could accelerate developments in nanomedicine, similarly to what happened with the Human Genome and other -omics projects, on issues like exchanging modeling and simulation methods and tools, linking toxicity information to clinical and personal databases or developing new approaches for scientific ontologies, among many others
All-Payer Claims Databases: State Initiatives to Improve Health Care Transparency
Examines states' efforts to support transparency and reform by developing claims databases with comprehensive information on disease incidence, utilization patterns, costs, and health outcomes. Outlines benefits, models, and implementation challenges
Cultural heritage and sustainable development targets : a possible harmonisation? Insights from the European Perspective
The Agenda 2030 includes a set of targets that need to be achieved by 2030. Although none
of the 17 Sustainable Development Goals (SDGs) focuses exclusively on cultural heritage, the
resulting Agenda includes explicit reference to heritage in SDG 11.4 and indirect reference to other
Goals. Achievement of international targets shall happen at local and national level, and therefore,
it is crucial to understand how interventions on local heritage are monitored nationally, therefore
feeding into the sustainable development framework. This paper is focused on gauging the
implementation of the Sustainable Development Goals with reference to cultural heritage, by
interrogating the current way of classifying it (and consequently monitoring). In fact, there is no
common dataset associated with monitoring SDGs, and the field of heritage is extremely complex
and diversified. The purpose for the paper is to understand if the taxonomy used by different
national databases allows consistency in the classification and valuing of the different assets
categories. The European case study has been chosen as field of investigation, in order to pilot a
methodology that can be expanded in further research. A crossâcomparison of a selected sample of
publicly accessible national cultural heritage databases has been conducted. As a result, this study
confirms the existence of general harmonisation of data towards the achievement of the SDGs with
a broad agreement of the conceptualisation of cultural heritage with international frameworks, thus
confirming that consistency exists in the classification and valuing of the different assets categories.
However, diverse challenges of achieving a consistent and coherent approach to integrating culture
in sustainability remains problematic. The findings allow concluding that it could be possible to
mainstream across different databases those indicators, which could lead to depicting the overall
level of attainment of the Agenda 2030 targets on heritage. However, more research is needed in
developing a robust correlation between national datasets and international targets
Schema architecture and their relationships to transaction processing in distributed database systems
We discuss the different types of schema architectures which could be supported by distributed database systems, making a clear distinction between logical, physical, and federated distribution. We elaborate on the additional mapping information required in architecture based on logical distribution in order to support retrieval as well as update operations. We illustrate the problems in schema integration and data integration in multidatabase systems and discuss their impact on query processing. Finally, we discuss different issues relevant to the cooperation (or noncooperation) of local database systems in a heterogeneous multidatabase system and their relationship to the schema architecture and transaction processing
Interoperability, Trust Based Information Sharing Protocol and Security: Digital Government Key Issues
Improved interoperability between public and private organizations is of key
significance to make digital government newest triumphant. Digital Government
interoperability, information sharing protocol and security are measured the
key issue for achieving a refined stage of digital government. Flawless
interoperability is essential to share the information between diverse and
merely dispersed organisations in several network environments by using
computer based tools. Digital government must ensure security for its
information systems, including computers and networks for providing better
service to the citizens. Governments around the world are increasingly
revolving to information sharing and integration for solving problems in
programs and policy areas. Evils of global worry such as syndrome discovery and
manage, terror campaign, immigration and border control, prohibited drug
trafficking, and more demand information sharing, harmonization and cooperation
amid government agencies within a country and across national borders. A number
of daunting challenges survive to the progress of an efficient information
sharing protocol. A secure and trusted information-sharing protocol is required
to enable users to interact and share information easily and perfectly across
many diverse networks and databases globally.Comment: 20 page
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