Algorithms on determining the correlation laws between ultrasonic images and quality of spot welds.

Conventional quality control devices for spot welding cannot perform on-line inspection and provide feedback to the welding control system. In this way, the traditional quality control systems are similar to statistical welding parameters monitoring systems. It is imperative to combine the idea of on-line quality inspection with closed-loop feedback control in a robust control system. However, there is no single acoustic method to date capable of manipulating real-time control and on-line quality inspection, concurrently, since specific procedures (e.g. scanning time and adjustment time) need to be adopted by traditional acoustic microscopes to retrieve proper information, and these procedures tend to disable the real-time and on-line capability of acoustic microscopy. With recent hardware improvements, the novel portable acoustic device is able to reduce the scanning time to real-time fashion without losing any significant data. On the other hand, the adjustment time of the portable acoustic device can be reduced noticeably by employing intelligent control software instead of human operators. This new hardware-software configuration will be an ideal approach to the on-line, real-time nondestructive inspection of spot welds. The primary goal of this research is to develop an intelligent system to accomplish the on-line, real-time nondestructive inspection for spot welds. The following objectives were fulfilled to reach the final goal. (1) Classification of the acoustic images of spot welds. (2) Quantification of acoustic information as parameters. (3) The study of the influence of each parameter on the strength of spot welds. (4) Identification of important and significant parameters. (5) Integration of these parameters into the knowledge base of the software. The system developed can be an on-line advisor that is capable of providing critical information about the quality of spot welds during the process. Furthermore, this system is able to render warning signals to the process control unit to prevent further mistakes.Dept. of Industrial and Manufacturing Systems Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1999 .L33. Source: Dissertation Abstracts International, Volume: 66-02, Section: B, page: 1132. Advisers: Roman Maev; Michael Wang. Thesis (Ph.D.)--University of Windsor (Canada), 1999

Normal tissue complication models for clinically relevant acute esophagitis (>= grade 2) in patients treated with dose differentiated accelerated radiotherapy (DART-bid)

Background: One of the primary dose-limiting toxicities during thoracic irradiation is acute esophagitis (AE). The aim of this study is to investigate dosimetric and clinical predictors for AE grade >= 2 in patients treated with accelerated radiotherapy for locally advanced non-small cell lung cancer (NSCLC). Patients and methods: 66 NSCLC patients were included in the present analysis: 4 stage II, 44 stage IIIA and 18 stage IIIB. All patients received induction chemotherapy followed by dose differentiated accelerated radiotherapy (DART-bid). Depending on size (mean of three perpendicular diameters) tumors were binned in four dose groups: 6 cm 90 Gy. Patients were treated in 3D target splitting technique. In order to estimate the normal tissue complication probability (NTCP),two Lyman models and the cutoff-logistic regression model were fitted to the data with AE >= grade 2 as statistical endpoint. Inter-model comparison was performed with the corrected Akaike information criterion (AIC(c)),which calculates the model's quality of fit (likelihood value) in relation to its complexity (i.e. number of variables in the model) corrected by the number of patients in the dataset. Toxicity was documented prospectively according to RTOG. Results: The median follow up was 686 days (range 84-2921 days), 23/66 patients (35 %) experienced AE >= grade 2. The actuarial local control rates were 72.6 % and 59.4 % at 2 and 3 years, regional control was 91 % at both time points. The Lyman-MED model (D50 = 32.8 Gy, m = 0.48) and the cutoff dose model (D-c = 38 Gy) provide the most efficient fit to the current dataset. On multivariate analysis V38 (volume of the esophagus that receives 38 Gy or above, 95 %-CI 28.2-57.3) was the most significant predictor of AE >= grade 2 (HR = 1.05, CI 1.01-1.09, p = 0.007). Conclusion: Following high-dose accelerated radiotherapy the rate of AE >= grade 2 is slightly lower than reported for concomitant radio-chemotherapy with the additional benefit of markedly increased loco-regional tumor control. In the current patient cohort the most significant predictor of AE was found to be V38. A second clinically useful parameter in treatment planning may be MED (mean esophageal dose)

Dose escalation to high-risk sub-volumes based on non-invasive imaging of hypoxia and glycolytic activity in canine solid tumors:a feasibility study

INTRODUCTION: Glycolytic activity and hypoxia are associated with poor prognosis and radiation resistance. Including both the tumor uptake of 2-deoxy-2-[(18) F]-fluorodeoxyglucose (FDG) and the proposed hypoxia tracer copper(II)diacetyl-bis(N(4))-methylsemithio-carbazone (Cu-ATSM) in targeted therapy planning may therefore lead to improved tumor control. In this study we analyzed the overlap between sub-volumes of FDG and hypoxia assessed by the uptake of (64)Cu-ATSM in canine solid tumors, and evaluated the possibilities for dose redistribution within the gross tumor volume (GTV). MATERIALS AND METHODS: Positron emission tomography/computed tomography (PET/CT) scans of five spontaneous canine solid tumors were included. FDG-PET/CT was obtained at day 1, (64)Cu-ATSM at day 2 and 3 (3 and 24 h pi.). GTV was delineated and CT images were co-registered. Sub-volumes for 3 h and 24 h (64)Cu-ATSM (Cu3 and Cu24) were defined by a threshold based method. FDG sub-volumes were delineated at 40% (FDG40) and 50% (FDG50) of SUV(max). The size of sub-volumes, intersection and biological target volume (BTV) were measured in a treatment planning software. By varying the average dose prescription to the tumor from 66 to 85 Gy, the possible dose boost (D( B )) was calculated for the three scenarios that the optimal target for the boost was one, the union or the intersection of the FDG and (64)Cu-ATSM sub-volumes. RESULTS: The potential boost volumes represented a fairly large fraction of the total GTV: Cu3 49.8% (26.8-72.5%), Cu24 28.1% (2.4-54.3%), FDG40 45.2% (10.1-75.2%), and FDG50 32.5% (2.6-68.1%). A BTV including the union (∪) of Cu3 and FDG would involve boosting to a larger fraction of the GTV, in the case of Cu3∪FDG40 63.5% (51.8-83.8) and Cu3∪FDG50 48.1% (43.7-80.8). The union allowed only a very limited D( B ) whereas the intersection allowed a substantial dose escalation. CONCLUSIONS: FDG and (64)Cu-ATSM sub-volumes were only partly overlapping, suggesting that the tracers offer complementing information on tumor physiology. Targeting the combined PET positive volume (BTV) for dose escalation within the GTV results in a limited D( B ). This suggests a more refined dose redistribution based on a weighted combination of the PET tracers in order to obtain an improved tumor control

Potential of Roof Rain Water Harvesting at an Industrial Setup

This study examined the Roof Rain Water Harvesting (RRWH) prospective at textile mill alongside with the assessment of legal framework on RWH. The following information was analyzed:  Decadal rainfall variability, Rainfall probability, Rainwater quality (pH, Total Suspended Solids (TSS), hardness, Iron, Manganese and Lead). The metals were analyzed by Atomic Absorption Spectrophotometer, the rest of the parameters were analysed according to APHA (1997).  Volume of rainwater tank was chosen using Rapid Depletion Method.  Topographical survey of the site was done using standard Spot Height method. The Weibull formula was applied for plotting positions. The Hydrological Vertical Electrical Survey of the site was conducted with Standard Terresmeter. The average monthly rainfall was found at 91mm, which is higher than 50 mm recommended by Kenya Rainwater Association. Jointly with rainfall probability of 66% it was concluded that RWH was feasible. All the rainwater test results were within the stipulated standards, with exception of TSS, which exceeded the standard by 294%. To address this issue the study designed First flush off system and three layer Roughing filter. The payback period was found reasonably attractive - 5.6 years, thus the study recommended RRWH reinforced concrete system as a supplementary source of water at the mill with economic profit due to reduction of water utility bill. In addition environmental benefits can be obtained, such as control of storm water and decrease of vector borne diseases, e.g. malaria, which was not quantified.  Specific recommendations were made in order to promote and scale up RWH in Kenya. Keywords: Roof Rainwater Harvesting, industry

Brain structure, IQ, and psychopathology in young offspring of patients with schizophrenia or bipolar disorder

BACKGROUND.: Studying offspring of schizophrenia (SZo) and bipolar disorder patients (BDo) provides important information on the putative neurodevelopmental trajectories underlying development toward severe mental illnesses. We compared intracranial volume (ICV), as a marker for neurodevelopment, and global and local brain measures between SZo or BDo and control offspring (Co) in relation to IQ and psychopathology. METHODS.: T1-weighted magnetic resonance imaging (MRI) brain scans were obtained from 146 participants (8-19 years; 40 SZo, 66 BDo, 40 Co). Linear mixed models were applied to compare ICV, global, and local brain measures between groups. To investigate the effect of ICV, IQ (four subtests Wechsler Intelligence Scale for Children/Wechsler Adult Intelligence Scale-III) or presence of psychopathology these variables were each added to the model. RESULTS.: SZo and BDo had significantly lower IQ and more often met criteria for a lifetime psychiatric disorder than Co. ICV was significantly smaller in SZo than in BDo (d = -0.56) and Co (d = -0.59), which was largely independent of IQ (respectively, d = -0.54 and d = -0.35). After ICV correction, the cortex was significantly thinner in SZo than in BDo (d = -0.42) and Co (d = -0.75) and lateral ventricles were larger in BDo than in Co (d = 0.55). Correction for IQ or lifetime psychiatric diagnosis did not change these findings. CONCLUSIONS.: Despite sharing a lower IQ and a higher prevalence of psychiatric disorders, brain abnormalities in BDo appear less pronounced (but are not absent) than in SZo. Lower ICV in SZo implies that familial risk for schizophrenia has a stronger association with stunted early brain development than familial risk for bipolar disorder

Combining behavioural types with security analysis

Today's software systems are highly distributed and interconnected, and they increasingly rely on communication to achieve their goals; due to their societal importance, security and trustworthiness are crucial aspects for the correctness of these systems. Behavioural types, which extend data types by describing also the structured behaviour of programs, are a widely studied approach to the enforcement of correctness properties in communicating systems. This paper offers a unified overview of proposals based on behavioural types which are aimed at the analysis of security properties

Hippocampal sclerosis affects fMR-adaptation of lyrics and melodies in songs

Songs constitute a natural combination of lyrics and melodies, but it is unclear whether and how these two song components are integrated during the emergence of a memory trace. Network theories of memory suggest a prominent role of the hippocampus, together with unimodal sensory areas, in the build-up of conjunctive representations. The present study tested the modulatory influence of the hippocampus on neural adaptation to songs in lateral temporal areas. Patients with unilateral hippocampal sclerosis and healthy matched controls were presented with blocks of short songs in which lyrics and/or melodies were varied or repeated in a crossed factorial design. Neural adaptation effects were taken as correlates of incidental emergent memory traces. We hypothesized that hippocampal lesions, particularly in the left hemisphere, would weaken adaptation effects, especially the integration of lyrics and melodies. Results revealed that lateral temporal lobe regions showed weaker adaptation to repeated lyrics as well as a reduced interaction of the adaptation effects for lyrics and melodies in patients with left hippocampal sclerosis. This suggests a deficient build-up of a sensory memory trace for lyrics and a reduced integration of lyrics with melodies, compared to healthy controls. Patients with right hippocampal sclerosis showed a similar profile of results although the effects did not reach significance in this population. We highlight the finding that the integrated representation of lyrics and melodies typically shown in healthy participants is likely tied to the integrity of the left medial temporal lobe. This novel finding provides the first neuroimaging evidence for the role of the hippocampus during repetitive exposure to lyrics and melodies and their integration into a song

Strengthening HIV Knowledge and Awareness among Undergraduate Students at Historically Black Colleges and Universities

Objective: We describe baseline HIV knowledge among students at historically black colleges and universities (HBCUs) to inform and strengthen HIV education efforts at HBCUs. Methods: We surveyed 1,230 African American HBCU students from 24 HBCUs; 1,051 responses (85.4 %) were analyzable. Results: Although general HIV knowledge was high among respondents (95% of students correctly responded that having sex without a condom constituted unsafe sex), knowledge deficits were noted (only 25% of students reported that multiple sex partners is a form of unsafe sex, while 25% of students reported that withdrawal of the penis before ejaculation reduced HIV risk). Conclusions: Misperceptions about HIV have implications for unintended sexual transmission of HIV. As African American young adults are disproportionately affected by HIV, strengthening HIV prevention efforts at HBCUs may include correcting misperceptions to reduce sexual risk and decrease HIV-related health disparities among young people

A survey on gain-scheduled control and filtering for parameter-varying systems

Copyright © 2014 Guoliang Wei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.This paper presents an overview of the recent developments in the gain-scheduled control and filtering problems for the parameter-varying systems. First of all, we recall several important algorithms suitable for gain-scheduling method including gain-scheduled proportional-integral derivative (PID) control, H 2, H ∞ and mixed H 2 / H ∞ gain-scheduling methods as well as fuzzy gain-scheduling techniques. Secondly, various important parameter-varying system models are reviewed, for which gain-scheduled control and filtering issues are usually dealt with. In particular, in view of the randomly occurring phenomena with time-varying probability distributions, some results of our recent work based on the probability-dependent gain-scheduling methods are reviewed. Furthermore, some latest progress in this area is discussed. Finally, conclusions are drawn and several potential future research directions are outlined.The National Natural Science Foundation of China under Grants 61074016, 61374039, 61304010, and 61329301; the Natural Science Foundation of Jiangsu Province of China under Grant BK20130766; the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning; the Program for New Century Excellent Talents in University under Grant NCET-11-1051, the Leverhulme Trust of the U.K., the Alexander von Humboldt Foundation of Germany